| The role of FoxO in the regulation of metabolism DN Gross, APJ Van Den Heuvel, MJ Birnbaum Oncogene 27 (16), 2320-2336, 2008 | 672 | 2008 |
| Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities B Hong, PJ van den Heuvel, V V Prabhu, S Zhang, W S El-Deiry Current drug targets 15 (1), 80-89, 2014 | 291 | 2014 |
| Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth APJ van den Heuvel, J Jing, RF Wooster, KE Bachman Cancer Biology & Therapy 13 (12), 0--1, 2012 | 265 | 2012 |
| ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases CLB Kline, APJ Van den Heuvel, JE Allen, VV Prabhu, DT Dicker, ... Science signaling 9 (415), ra18-ra18, 2016 | 187 | 2016 |
| Small-molecule NSC59984 restores p53 pathway signaling and antitumor effects against colorectal cancer via p73 activation and degradation of mutant p53 S Zhang, L Zhou, B Hong, APJ van den Heuvel, VV Prabhu, NA Warfel, ... Cancer research 75 (18), 3842-3852, 2015 | 112 | 2015 |
| Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53 B Hong, VV Prabhu, S Zhang, APJ van den Heuvel, DT Dicker, ... Cancer research 74 (4), 1153-1165, 2014 | 93 | 2014 |
| Direct control of caveolin-1 expression by FOXO transcription factors APJ Van Den Heuvel, A Schulze, BMT Burgering Biochemical Journal 385 (Pt 3), 795, 2005 | 81 | 2005 |
| Binding of protein kinase B to the plakin family member periplakin APJ van den Heuvel, AMM de Vries-Smits, PC van Weeren, PF Dijkers, ... Journal of cell science 115 (20), 3957-3966, 2002 | 77 | 2002 |
| Genetic and pharmacological screens converge in identifying FLIP, BCL2, and IAP proteins as key regulators of sensitivity to the TRAIL-inducing anticancer agent ONC201/TIC10 JE Allen, VV Prabhu, M Talekar, APJ Van Den Heuvel, B Lim, DT Dicker, ... Cancer research 75 (8), 1668-1674, 2015 | 48 | 2015 |
| Novel Common Integration Sites Targeted by Mouse Mammary Tumor Virus Insertion in Mammary Tumors Have Oncogenic Activity HH Kim, APJ van den Heuvel, JW Schmidt, SR Ross PloS one 6 (11), e27425, 2011 | 31 | 2011 |
| Early integrated stress response induction of ATF4 is required for the anticancer effects of the dual Akt/ERK inhibitor and TRAIL pathway inducer ONC201/TIC10 CL Kline, P van den Heuvel, JE Allen, DT Dicker, WS El-Deiry Cancer Research 75 (15_Supplement), 674-674, 2015 | | 2015 |
