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Daniel Schramek
Daniel Schramek
Senior Investigator & Assoc. Prof. Mount Sinai Hospital/University of Toronto
在 lunenfeld.ca 的电子邮件经过验证 - 首页
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引用次数
引用次数
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Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ...
Nature 468 (7320), 98-102, 2010
6382010
A dual role for autophagy in a murine model of lung cancer
S Rao, L Tortola, T Perlot, G Wirnsberger, M Novatchkova, R Nitsch, ...
Nature communications 5 (1), 3056, 2014
4392014
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate
JA Pospisilik, D Schramek, H Schnidar, SJF Cronin, NT Nehme, X Zhang, ...
Cell 140 (1), 148-160, 2010
4172010
Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection
SJF Cronin, NT Nehme, S Limmer, S Liegeois, JA Pospisilik, D Schramek, ...
Science 325 (5938), 340-343, 2009
3632009
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene
GG Neely, A Hess, M Costigan, AC Keene, S Goulas, M Langeslag, ...
Cell 143 (4), 628-638, 2010
3472010
Translation from unconventional 5′ start sites drives tumour initiation
A Sendoel, JG Dunn, EH Rodriguez, S Naik, NC Gomez, B Hurwitz, ...
Nature 541 (7638), 494-499, 2017
3032017
Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas
D Schramek, A Sendoel, JP Segal, S Beronja, E Heller, D Oristian, ...
Science 343 (6168), 309-313, 2014
3002014
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells
U Elling, J Taubenschmid, G Wirnsberger, R O'Malley, SP Demers, ...
Cell stem cell 9 (6), 563-574, 2011
2762011
Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome
T Gayden, FE Sepulveda, DA Khuong-Quang, J Pratt, ET Valera, ...
Nature genetics 50 (12), 1650-1657, 2018
1852018
RANKL/RANK control Brca1 mutation-driven mammary tumors
V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ...
Cell research 26 (7), 761-774, 2016
1632016
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ...
Nature communications 11 (1), 3701, 2020
1612020
Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling
SK Loganathan, K Schleicher, A Malik, R Quevedo, E Langille, K Teng, ...
Science 367 (6483), 1264-1269, 2020
1582020
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis
B Grabner, D Schramek, KM Mueller, HP Moll, J Svinka, T Hoffmann, ...
Nature communications 6 (1), 6285, 2015
1582015
RANKL/RANK—beyond bones
R Hanada, T Hanada, V Sigl, D Schramek, JM Penninger
Journal of Molecular Medicine 89, 647-656, 2011
1562011
Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein
T Brummer, D Schramek, VM Hayes, HL Bennett, CE Caldon, ...
Journal of Biological Chemistry 281 (1), 626-637, 2006
1432006
Afatinib restrains K-RAS–driven lung tumorigenesis
HP Moll, K Pranz, M Musteanu, B Grabner, N Hruschka, J Mohrherr, ...
Science translational medicine 10 (446), eaao2301, 2018
1242018
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ...
Development 140 (7), 1397-1401, 2013
1172013
The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression
D Schramek, A Kotsinas, A Meixner, T Wada, U Elling, JA Pospisilik, ...
Nature genetics 43 (3), 212-219, 2011
1152011
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens
G Michlits, M Hubmann, SH Wu, G Vainorius, E Budusan, S Zhuk, ...
Nature methods 14 (12), 1191-1197, 2017
1102017
Binary pan-cancer classes with distinct vulnerabilities defined by pro-or anti-cancer YAP/TEAD activity
JD Pearson, K Huang, M Pacal, SR McCurdy, S Lu, A Aubry, T Yu, ...
Cancer Cell 39 (8), 1115-1134. e12, 2021
1072021
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