Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation K Haglund, S Sigismund, S Polo, I Szymkiewicz, PP Di Fiore, I Dikic Nature cell biology 5 (5), 461-466, 2003 | 1068 | 2003 |
Clathrin-independent endocytosis of ubiquitinated cargos S Sigismund, T Woelk, C Puri, E Maspero, C Tacchetti, P Transidico, ... Proceedings of the National Academy of Sciences 102 (8), 2760-2765, 2005 | 1037 | 2005 |
Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation S Sigismund, E Argenzio, D Tosoni, E Cavallaro, S Polo, PP Di Fiore Developmental cell 15 (2), 209-219, 2008 | 809 | 2008 |
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins S Polo, S Sigismund, M Faretta, M Guidi, MR Capua, G Bossi, H Chen, ... Nature 416 (6879), 451-455, 2002 | 809 | 2002 |
When ubiquitin meets ubiquitin receptors: a signalling connection PP Di Fiore, S Polo, K Hofmann Nature reviews Molecular cell biology 4 (6), 491-497, 2003 | 421 | 2003 |
Endocytosis and signaling: cell logistics shape the eukaryotic cell plan S Sigismund, S Confalonieri, A Ciliberto, S Polo, G Scita, PP Di Fiore Physiological reviews 92 (1), 273-366, 2012 | 369 | 2012 |
Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin L Penengo, M Mapelli, AG Murachelli, S Confalonieri, L Magri, ... Cell 124 (6), 1183-1195, 2006 | 338 | 2006 |
Endocytosis conducts the cell signaling orchestra S Polo, PP Di Fiore cell 124 (5), 897-900, 2006 | 299 | 2006 |
Ubiquitin in trafficking: the network at work F Acconcia, S Sigismund, S Polo Experimental cell research 315 (9), 1610-1618, 2009 | 266 | 2009 |
Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes M Innocenti, S Gerboth, K Rottner, FPL Lai, M Hertzog, TEB Stradal, ... Nature cell biology 7 (10), 969-976, 2005 | 251 | 2005 |
Molecular mechanisms of coupled monoubiquitination T Woelk, B Oldrini, E Maspero, S Confalonieri, E Cavallaro, PP Di Fiore, ... Nature cell biology 8 (11), 1246-1254, 2006 | 247 | 2006 |
USP15 is a deubiquitylating enzyme for receptor-activated SMADs M Inui, A Manfrin, A Mamidi, G Martello, L Morsut, S Soligo, E Enzo, ... Nature cell biology 13 (11), 1368-1375, 2011 | 229 | 2011 |
Signaling through monoubiquitination S Sigismund, S Polo, PP Di Fiore Signalling from internalized growth factor receptors, 149-185, 2004 | 227 | 2004 |
The ubiquitination code: a signalling problem T Woelk, S Sigismund, L Penengo, S Polo Cell division 2, 1-12, 2007 | 216 | 2007 |
Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain Y Mao, F Senic-Matuglia, PP Di Fiore, S Polo, ME Hodsdon, P De Camilli Proceedings of the National Academy of Sciences 102 (36), 12700-12705, 2005 | 214 | 2005 |
Threshold‐controlled ubiquitination of the EGFR directs receptor fate S Sigismund, V Algisi, G Nappo, A Conte, R Pascolutti, A Cuomo, ... The EMBO journal 32 (15), 2140-2157, 2013 | 208 | 2013 |
N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits S Benesch, S Polo, FPL Lai, KI Anderson, TEB Stradal, J Wehland, ... Journal of cell science 118 (14), 3103-3115, 2005 | 206 | 2005 |
Structure of the HECT: ubiquitin complex and its role in ubiquitin chain elongation E Maspero, S Mari, E Valentini, A Musacchio, A Fish, S Pasqualato, ... EMBO reports 12 (4), 342-349, 2011 | 199 | 2011 |
Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming E Maspero, E Valentini, S Mari, V Cecatiello, P Soffientini, S Pasqualato, ... Nature structural & molecular biology 20 (6), 696-701, 2013 | 198 | 2013 |
C–C chemokines released by lipopolysaccharide (LPS)-stimulated human macrophages suppress HIV-1 infection in both macrophages and T cells A Verani, G Scarlatti, M Comar, E Tresoldi, S Polo, M Giacca, P Lusso, ... The Journal of experimental medicine 185 (5), 805-816, 1997 | 194 | 1997 |