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Shih-Yu (Shirley) Chang
Shih-Yu (Shirley) Chang
未知所在单位机构
在 uw.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity
SY Chang, EJ Weber, VS Sidorenko, A Chapron, CK Yeung, C Gao, ...
JCI insight 2 (22), 2017
1532017
Liver and kidney on chips: microphysiological models to understand transporter function
SY Chang, EJ Weber, KPV Ness, DL Eaton, EJ Kelly
Clinical Pharmacology & Therapeutics 100 (5), 464-478, 2016
682016
Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination …
J Zou, YW Pan, Z Wang, SY Chang, W Wang, X Wang, C Tournier, ...
Journal of Neuroscience 32 (12), 4118-4132, 2012
562012
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity
SY Chang, JL Voellinger, KP Van Ness, B Chapron, RM Shaffer, ...
Toxicology in Vitro 40, 170-183, 2017
382017
Ectopic expression of interleukin-1 receptor type II enhances cell migration through activation of the pre-interleukin 1α pathway
SY Chang, PF Su, TC Lee
Cytokine 45 (1), 32-38, 2009
312009
Microphysiological systems to assess nonclinical toxicity
KP Van Ness, SY Chang, EJ Weber, D Zumpano, DL Eaton, EJ Kelly
Current protocols in toxicology 73 (1), 14.18. 1-14.18. 28, 2017
272017
An improved vascularized, dual-channel microphysiological system facilitates modeling of proximal tubular solute secretion
A Chapron, BD Chapron, DW Hailey, SY Chang, T Imaoka, KE Thummel, ...
ACS pharmacology & translational science 3 (3), 496-508, 2020
242020
Enhanced suppression of tumor growth by concomitant treatment of human lung cancer cells with suberoylanilide hydroxamic acid and arsenic trioxide
CW Chien, JH Yao, SY Chang, PC Lee, TC Lee
Toxicology and applied pharmacology 257 (1), 59-66, 2011
202011
Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system
T Imaoka, W Huang, S Shum, DW Hailey, SY Chang, A Chapron, ...
Scientific Reports 11 (1), 21356, 2021
182021
Incorporating uremic solute-mediated inhibition of OAT1/3 improves PBPK prediction of tenofovir renal and systemic disposition in patients with severe kidney disease
SY Chang, W Huang, A Chapron, AJL Quiñones, J Wang, N Isoherranen, ...
Pharmaceutical Research 40 (11), 2597-2606, 2023
12023
Predicting renal clearance of morphine and morphine‐6‐glucuronide using the “organ‐on‐a‐chip” technology and physiologically‐based pharmacokinetic modeling
S Shum, T Imaoka, W Huang, SY Chang, C Yeung, J Himmelfarb, E Kelly, ...
The FASEB Journal 34 (S1), 1-1, 2020
2020
P7-Utilization of a microphysiological system to model renal secretion of opioids in humans
T Imaoka, S Shum, SY Chang, A Chapron, CK Yeung, J Himmelfarb, ...
Drug Metabolism and Pharmacokinetics 35 (1), S24, 2020
2020
P226-Investigating uremic solute-drugs interaction using in vitro transporter assays
SY Chang, A Chapron, T Imaoka, CK Yeung
Drug Metabolism and Pharmacokinetics 35 (1), S90-S91, 2020
2020
In vitro Transporter Screens to Investigate Uremic Solute‐Drugs Interaction
SY Chang, A Chapron, TI Imaoka, CK Yeung
The FASEB Journal 33 (S1), 507.1-507.1, 2019
2019
Desenvolvimento de um sistema microfisiológico orgânico duplo de Kidney para prever interações de órgãos-órgãos na toxicidade dos xenobióticos: nefrotoxicidade do ácido …
S Chang
2016
Development of a Liver-Kidney Dual Organ Microphysiological System for Predicting Organ-Organ Interactions in the Toxicity of Xenobiotics: Aristolochic Acid Nephrotoxicity as a …
SY Chang
2016
Ectopic expression of interleukin 1 receptor type II enhances cell migration through activation of pre-interleukin 1α pathway
PF Su, SY Chang, TC Lee
Cancer Research 68 (9_Supplement), 5386-5386, 2008
2008
The roles of type 2 IL-1 receptor in human urothelial cells exposed to arsenite
SY Chang, PF Su, TC Lee
Cancer Research 67 (9_Supplement), 2036-2036, 2007
2007
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