Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity SY Chang, EJ Weber, VS Sidorenko, A Chapron, CK Yeung, C Gao, ... JCI insight 2 (22), 2017 | 153 | 2017 |
Liver and kidney on chips: microphysiological models to understand transporter function SY Chang, EJ Weber, KPV Ness, DL Eaton, EJ Kelly Clinical Pharmacology & Therapeutics 100 (5), 464-478, 2016 | 68 | 2016 |
Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination … J Zou, YW Pan, Z Wang, SY Chang, W Wang, X Wang, C Tournier, ... Journal of Neuroscience 32 (12), 4118-4132, 2012 | 56 | 2012 |
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity SY Chang, JL Voellinger, KP Van Ness, B Chapron, RM Shaffer, ... Toxicology in Vitro 40, 170-183, 2017 | 38 | 2017 |
Ectopic expression of interleukin-1 receptor type II enhances cell migration through activation of the pre-interleukin 1α pathway SY Chang, PF Su, TC Lee Cytokine 45 (1), 32-38, 2009 | 31 | 2009 |
Microphysiological systems to assess nonclinical toxicity KP Van Ness, SY Chang, EJ Weber, D Zumpano, DL Eaton, EJ Kelly Current protocols in toxicology 73 (1), 14.18. 1-14.18. 28, 2017 | 27 | 2017 |
An improved vascularized, dual-channel microphysiological system facilitates modeling of proximal tubular solute secretion A Chapron, BD Chapron, DW Hailey, SY Chang, T Imaoka, KE Thummel, ... ACS pharmacology & translational science 3 (3), 496-508, 2020 | 24 | 2020 |
Enhanced suppression of tumor growth by concomitant treatment of human lung cancer cells with suberoylanilide hydroxamic acid and arsenic trioxide CW Chien, JH Yao, SY Chang, PC Lee, TC Lee Toxicology and applied pharmacology 257 (1), 59-66, 2011 | 20 | 2011 |
Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system T Imaoka, W Huang, S Shum, DW Hailey, SY Chang, A Chapron, ... Scientific Reports 11 (1), 21356, 2021 | 18 | 2021 |
Incorporating uremic solute-mediated inhibition of OAT1/3 improves PBPK prediction of tenofovir renal and systemic disposition in patients with severe kidney disease SY Chang, W Huang, A Chapron, AJL Quiñones, J Wang, N Isoherranen, ... Pharmaceutical Research 40 (11), 2597-2606, 2023 | 1 | 2023 |
Predicting renal clearance of morphine and morphine‐6‐glucuronide using the “organ‐on‐a‐chip” technology and physiologically‐based pharmacokinetic modeling S Shum, T Imaoka, W Huang, SY Chang, C Yeung, J Himmelfarb, E Kelly, ... The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
P7-Utilization of a microphysiological system to model renal secretion of opioids in humans T Imaoka, S Shum, SY Chang, A Chapron, CK Yeung, J Himmelfarb, ... Drug Metabolism and Pharmacokinetics 35 (1), S24, 2020 | | 2020 |
P226-Investigating uremic solute-drugs interaction using in vitro transporter assays SY Chang, A Chapron, T Imaoka, CK Yeung Drug Metabolism and Pharmacokinetics 35 (1), S90-S91, 2020 | | 2020 |
In vitro Transporter Screens to Investigate Uremic Solute‐Drugs Interaction SY Chang, A Chapron, TI Imaoka, CK Yeung The FASEB Journal 33 (S1), 507.1-507.1, 2019 | | 2019 |
Desenvolvimento de um sistema microfisiológico orgânico duplo de Kidney para prever interações de órgãos-órgãos na toxicidade dos xenobióticos: nefrotoxicidade do ácido … S Chang | | 2016 |
Development of a Liver-Kidney Dual Organ Microphysiological System for Predicting Organ-Organ Interactions in the Toxicity of Xenobiotics: Aristolochic Acid Nephrotoxicity as a … SY Chang | | 2016 |
Ectopic expression of interleukin 1 receptor type II enhances cell migration through activation of pre-interleukin 1α pathway PF Su, SY Chang, TC Lee Cancer Research 68 (9_Supplement), 5386-5386, 2008 | | 2008 |
The roles of type 2 IL-1 receptor in human urothelial cells exposed to arsenite SY Chang, PF Su, TC Lee Cancer Research 67 (9_Supplement), 2036-2036, 2007 | | 2007 |