Tobias L Lenz 个人学术档案

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Christophe EizaguirreSchool of Biological and Behavioural Sciences, Queen Mary University of London在 qmul.ac.uk 的电子邮件经过验证
manfred milinskiMPI Plön在 evolbio.mpg.de 的电子邮件经过验证
Thorsten BH ReuschProfessor Marine Ecology, GEOMAR Kiel在 geomar.de 的电子邮件经过验证
Federica PieriniMax Planck Institute for Evolutionary Anthropology在 eva.mpg.de 的电子邮件经过验证
Erich Bornberg-BauerProfessor of Molecular Evolution and Bioinformatics, University of muenster, Germany在 uni-muenster.de 的电子邮件经过验证
Philine G D FeulnerGroup leader, Eawag Swiss Federal Institute of Aquatic Science and Technology在 eawag.ch 的电子邮件经过验证
Mahesh Binzer-PanchalNational Bioinformatics Infrastructure Sweden, Uppsala University在 nbis.se 的电子邮件经过验证
Andre FrankeProfessor for Molecular Medicine, Christian-Albrechts-University of Kiel在 mucosa.de 的电子邮件经过验证
Ben Krause-KyoraProfessor of ancient DNA, Kiel University在 ikmb.uni-kiel.de 的电子邮件经过验证
Soumya RaychaudhuriHarvard Medical School; Brigham and Women's Hospital, Broad Institute在 broadinstitute.org 的电子邮件经过验证
Buhm HanDepartment of Biomedical Sciences, Seoul National University College of Medicine在 snu.ac.kr 的电子邮件经过验证
Paul I W de BakkerVertex Pharmaceuticals在 vrtx.com 的电子邮件经过验证
Joshka KaufmannUCC, Cork, Ireland在 ucc.ie 的电子邮件经过验证
Lukas FlatzUniversity of Tübingen (Medical Faculty)在 med.uni-tuebingen.de 的电子邮件经过验证
Shamil SunyaevProfessor of Biomedical Informatics and of Medicine (BWH), Harvard Medical School在 rics.bwh.harvard.edu 的电子邮件经过验证
Jatin AroraSenior Scientist at Boehringer Ingelheim. Previously at Broad and MPI for EvolBio.在 evolbio.mpg.de 的电子邮件经过验证
Claus WedekindUniversity of Lausanne在 unil.ch 的电子邮件经过验证
Chris HarrodUniversidad de Antofagasta, Instituto Ciencias Naturales Alexander von Humboldt在 harrodlab.net 的电子邮件经过验证
Arne TraulsenMax-Planck-Institute for Evolutionary Biology在 evolbio.mpg.de 的电子邮件经过验证
Michael NothnagelProfessor of Statistical Genetics / Bioinformatics, University of Cologne在 uni-koeln.de 的电子邮件经过验证

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Tobias L Lenz

Professor for Evolutionary Immunogenomics, Department of Biology, University of Hamburg

在 uni-hamburg.de 的电子邮件经过验证 - 首页

Evolutionary Genetics Immunogenomics Host-Parasite Coevolution


标题按引用次数排序按年份排序按标题排序	引用次数引用次数	年份
Genomewide Association Study of Severe Covid-19 with Respiratory Failure D Ellinghaus, F Degenhardt, L Bujanda, M Buti, A Albillos, P Invernizzi, ... New England Journal of Medicine 383, 1522-1534, 2020	1935*	2020
Mapping the human genetic architecture of COVID-19 COVID-19 Host Genetics Initiative Nature 600, 472-477, 2021	747*	2021
Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations C Eizaguirre, TL Lenz, M Kalbe, M Milinski Nature Communications 3, 621, 2012	308	2012
Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii I Seim, X Fang, Z Xiong, AV Lobanov, Z Huang, S Ma, Y Feng, ... Nature Communications 4, 2212, 2013	286	2013
Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk X Hu, AJ Deutsch, TL Lenz, S Onengut-Gumuscu, B Han, WM Chen, ... Nature Genetics 47 (8), 898-905, 2015	278	2015
Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy D Chowell, C Krishna, F Pierini, V Makarov, NA Rizvi, F Kuo, LGT Morris, ... Nature Medicine 25 (11), 1715-1720, 2019	242	2019
Advances in the evolutionary understanding of MHC polymorphism J Radwan, W Babik, J Kaufman, TL Lenz, J Winternitz Trends in Genetics 36 (4), 298-311, 2020	239	2020
MHC‐based mate choice combines good genes and maintenance of MHC polymorphism C Eizaguirre, SE Yeates, TL Lenz, M Kalbe, M Milinski Molecular Ecology 18 (15), 3316-3329, 2009	227	2009
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases TL Lenz, AJ Deutsch, B Han, X Hu, Y Okada, S Eyre, M Knapp, ... Nature Genetics 47 (9), 963-1099, 2015	212	2015
Divergent selection on locally adapted major histocompatibility complex immune genes experimentally proven in the field C Eizaguirre, TL Lenz, M Kalbe, M Milinski Ecology Letters 15 (7), 723-731, 2012	194	2012
Simple approach to reduce PCR artefact formation leads to reliable genotyping of MHC and other highly polymorphic loci—Implications for evolutionary analysis TL Lenz, S Becker Gene 427 (1), 117-123, 2008	181	2008
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load PJ McLaren, C Coulonges, I Bartha, TL Lenz, AJ Deutsch, A Bashirova, ... Proceedings of the National Academy of Sciences 112 (47), 14658-14663, 2015	178	2015
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types D Chowell, SK Yoo, C Valero, A Pastore, C Krishna, M Lee, D Hoen, ... Nature Biotechnology 40, 499-506, 2022	161	2022
Parasite diversity, patterns of MHC II variation and olfactory based mate choice in diverging three-spined stickleback ecotypes C Eizaguirre, TL Lenz, RD Sommerfeld, C Harrod, M Kalbe, M Milinski Evolutionary Ecology 25 (3), 605-622, 2011	156	2011
Human leukocyte antigen variation is associated with adverse events of checkpoint inhibitors O Hasan Ali, F Berner, D Bomze, M Faessler, S Diem, A Cozzio, M Jörger, ... European Journal of Cancer 107, 8-14, 2019	153	2019
Divergent allele advantage at human MHC genes: signatures of past and ongoing selection F Pierini, TL Lenz Molecular Biology and Evolution 35 (9), 2145-2158, 2018	151	2018
Genomics of Divergence along a Continuum of Parapatric Population Differentiation PGD Feulner, FJJ Chain, M Panchal, Y Huang, C Eizaguirre, M Kalbe, ... PLoS Genetics 11 (2), e1004966, 2015	148	2015
Major histocompatibility complex polymorphism: dynamics and consequences of parasite‐mediated local adaptation in fishes C Eizaguirre, TL Lenz Journal of Fish Biology 77 (9), 2023-2047, 2010	134	2010
Speciation accelerated and stabilized by pleiotropic major histocompatibility complex immunogenes C Eizaguirre, TL Lenz, A Traulsen, M Milinski Ecology Letters 12 (1), 5-12, 2009	127	2009
Exploring local immunological adaptation of two stickleback ecotypes by experimental infection and transcriptome‐wide digital gene expression analysis TL Lenz, C Eizaguirre, B Rotter, M Kalbe, M Milinski Molecular Ecology 22 (3), 774-786, 2013	106	2013

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