Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer A Bistrović, L Krstulović, A Harej, P Grbčić, M Sedić, S Koštrun, SK Pavelić, ... European journal of medicinal chemistry 143, 1616-1634, 2018 | 109 | 2018 |
Novel pyrimidine-2, 4-dione–1, 2, 3-triazole and furo [2, 3-d] pyrimidine-2-one–1, 2, 3-triazole hybrids as potential anti-cancer agents: synthesis, computational and X-ray … T Gregorić, M Sedić, P Grbčić, AT Paravić, SK Pavelić, M Cetina, ... European journal of medicinal chemistry 125, 1247-1267, 2017 | 95 | 2017 |
Preparation of Multifunctional N-Doped Carbon Quantum Dots from Citrus clementina Peel: Investigating Targeted Pharmacological Activities and the Potential Application for … S Šafranko, A Stanković, S Hajra, HJ Kim, I Strelec, M Dutour-Sikirić, ... Pharmaceuticals 14 (9), 857, 2021 | 40 | 2021 |
Dual sphingosine kinase inhibitor SKI-II enhances sensitivity to 5-fluorouracil in hepatocellular carcinoma cells via suppression of osteopontin and FAK/IGF-1R signalling P Grbčić, I Tomljanović, M Klobučar, SK Pavelić, K Lučin, M Sedić Biochemical and biophysical research communications 487 (4), 782-788, 2017 | 30 | 2017 |
Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and β1 integrin/FAK− mediated signalling M Klobučar, P Grbčić, SK Pavelić, N Jonjić, S Visentin, M Sedić Biochemical and biophysical research communications 503 (2), 843-848, 2018 | 26 | 2018 |
Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549 A Bistrović, P Grbčić, A Harej, M Sedić, S Kraljević-Pavelić, S Koštrun, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 271-285, 2018 | 26 | 2018 |
Bioactive sphingolipids as biomarkers predictive of disease severity and treatment response in cancer: current status and translational challenges M Sedić, P Grbčić, SK Pavelić Anticancer research 39 (1), 41-56, 2019 | 21 | 2019 |
Sphingosine 1-phosphate signaling and metabolism in chemoprevention and chemoresistance in colon cancer P Grbčić, M Sedić Molecules 25 (10), 2436, 2020 | 19 | 2020 |
Eco-friendly synthesis, in vitro anti-proliferative evaluation, and 3D-QSAR analysis of a novel series of monocationic 2-aryl/heteroaryl-substituted 6-(2-imidazolinyl … L Racané, L Ptiček, M Sedić, P Grbčić, S Kraljević Pavelić, B Bertoša, ... Molecular diversity 22, 723-741, 2018 | 18 | 2018 |
Purine and purine isostere derivatives of ferrocene: An evaluation of ADME, antitumor and electrochemical properties V Rep, M Piškor, H Šimek, P Mišetić, P Grbčić, J Padovan, ... Molecules 25 (7), 1570, 2020 | 16 | 2020 |
Metabolite characterization, antioxidant, anti-proliferative and enzyme inhibitory activities of Lophira lanceolata Tiegh. ex Keay extracts KI Sinan, LS Martinović, Ž Peršurić, SK Pavelić, P Grbčić, D Matulja, ... Industrial crops and products 158, 112982, 2020 | 15 | 2020 |
Amidino substituted 2-aminophenols: Biologically important building blocks for the amidino-functionalization of 2-substituted benzoxazoles L Ptiček, L Hok, P Grbčić, F Topić, M Cetina, K Rissanen, SK Pavelić, ... Organic & biomolecular chemistry 19 (12), 2784-2793, 2021 | 14 | 2021 |
Targeting ceramide metabolism in hepatocellular carcinoma: new points for therapeutic intervention P Grbčić, EPM Car, M Sedić Current medicinal chemistry 27 (39), 6611-6627, 2020 | 13 | 2020 |
Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles L Racané, V Rep, S Kraljević Pavelić, P Grbčić, I Zonjić, M Radić Stojković, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 1952-1967, 2021 | 12 | 2021 |
In Vitro Photodynamic Activity of N‐Methylated and N‐Oxidised Tripyridyl Porphyrins with Long Alkyl Chains and Their Inhibitory Activity in Sphingolipid Metabolism M Jelovica, P Grbčić, M Mušković, M Sedić, SK Pavelić, M Lončarić, ... ChemMedChem 13 (4), 360-372, 2018 | 12 | 2018 |
Synthesis and anti-proliferative effects of mono-and bis-purinomimetics targeting kinases A Bistrović, A Harej, P Grbčić, M Sedić, S Kraljević Pavelić, M Cetina, ... International journal of molecular sciences 18 (11), 2292, 2017 | 12 | 2017 |
The sphingosine kinase 2 inhibitor ABC294640 restores the sensitivity of BRAFV600E mutant colon cancer cells to vemurafenib by reducing AKT-mediated expression of nucleophosmin … P Grbčić, TO Eichmann, S Kraljević Pavelić, M Sedić International Journal of Molecular Sciences 22 (19), 10767, 2021 | 11 | 2021 |
Proteomic profiling of BRAFV600E mutant colon cancer cells reveals the involvement of nucleophosmin/c-Myc axis in modulating the response and resistance to BRAF inhibition by … P Grbčić, D Fučkar Čupić, T Gamberi, S Kraljević Pavelić, M Sedić International journal of molecular sciences 22 (12), 6174, 2021 | 10 | 2021 |
Treatment with medicinal mushroom extract mixture inhibits translation and reprograms metabolism in advanced colorectal cancer animal model as evidenced by tandem mass tags … B Jakopovic, A Horvatić, M Klobučar, A Gelemanović, P Grbčić, N Oršolić, ... Frontiers in pharmacology 11, 1202, 2020 | 9 | 2020 |
Chemical evaluation, antioxidant, antiproliferative, anti-inflammatory and antibacterial activities of organic extract and semi-purified fractions of the Adriatic sea fan … D Matulja, P Grbčić, K Bojanić, N Topić-Popović, R Čož-Rakovac, S Laclef, ... Molecules 26 (19), 5751, 2021 | 6 | 2021 |