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Caloric restriction delays age-related methylation drift S Maegawa, Y Lu, T Tahara, JT Lee, J Madzo, S Liang, J Jelinek, ... Nature communications 8 (1), 539, 2017 | 251 | 2017 |
Targeting CDK9 reactivates epigenetically silenced genes in cancer H Zhang, S Pandey, M Travers, H Sun, G Morton, J Madzo, W Chung, ... Cell 175 (5), 1244-1258. e26, 2018 | 200 | 2018 |
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma CJ Mariani, A Vasanthakumar, J Madzo, A Yesilkanal, T Bhagat, Y Yu, ... Cell reports 7 (5), 1343-1352, 2014 | 178 | 2014 |
Real-time quantitative PCR detection of WT1 gene expression in children with AML: prognostic significance, correlation with disease status and residual disease detection by … J Trka, M Kalinova, O Hrušák, J Zuna, O Krejčí, J Madžo, P Sedláček, ... Leukemia 16 (7), 1381-1389, 2002 | 148 | 2002 |
TET1-mediated hypomethylation activates oncogenic signaling in triple-negative breast cancer CR Good, S Panjarian, AD Kelly, J Madzo, B Patel, J Jelinek, JPJ Issa Cancer research 78 (15), 4126-4137, 2018 | 113 | 2018 |
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis J Madzo, H Liu, A Rodriguez, A Vasanthakumar, S Sundaravel, ... Cell reports 6 (1), 231-244, 2014 | 113 | 2014 |
TET2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor–binding sites in chronic myelomonocytic leukemia J Yamazaki, J Jelinek, Y Lu, M Cesaroni, J Madzo, F Neumann, R He, ... Cancer research 75 (14), 2833-2843, 2015 | 110 | 2015 |
Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity S He, Y Liu, L Meng, H Sun, Y Wang, Y Ji, J Purushe, P Chen, C Li, ... Nature communications 8 (1), 2125, 2017 | 98 | 2017 |
ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia J Zuna, J Madzo, O Krejci, Z Zemanova, M Kalinova, K Muzikova, ... Blood, The Journal of the American Society of Hematology 117 (1), 368-369, 2011 | 91 | 2011 |
Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer S Bhattacharyya, Y Yu, M Suzuki, N Campbell, J Mazdo, ... Nucleic acids research 41 (16), e157-e157, 2013 | 81 | 2013 |
Nerve injury-induced chronic pain is associated with persistent DNA methylation reprogramming in dorsal root ganglion J Garriga, G Laumet, SR Chen, Y Zhang, J Madzo, JPJ Issa, HL Pan, ... Journal of Neuroscience 38 (27), 6090-6101, 2018 | 73 | 2018 |
Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells O Krejci, J Starkova, B Otova, J Madzo, M Kalinova, O Hrusak, J Trka Leukemia 18 (3), 434-441, 2004 | 70 | 2004 |
TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer CG Chapman, CJ Mariani, F Wu, K Meckel, F Butun, A Chuang, J Madzo, ... Scientific reports 5 (1), 17568, 2015 | 69 | 2015 |
A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer CR Good, J Madzo, B Patel, S Maegawa, N Engel, J Jelinek, JPJ Issa Nucleic Acids Research 45 (14), 8269-8281, 2017 | 65 | 2017 |
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Transcriptional selectivity of epigenetic therapy in cancer T Sato, M Cesaroni, W Chung, S Panjarian, A Tran, J Madzo, Y Okamoto, ... Cancer research 77 (2), 470-481, 2017 | 60 | 2017 |
Slower molecular response to treatment predicts poor outcome in patients with TEL/AML1 positive acute lymphoblastic leukemia: Prospective real‐time quantitative reverse … J Madžo, J Zuna, K Mužíková, M Kalinová, O Krejčí, O Hrušák, B Otová, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2003 | 58 | 2003 |
Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells RJ Werner, BM Schultz, JM Huhn, J Jelinek, J Madzo, N Engel Biology of sex differences 8, 1-18, 2017 | 54 | 2017 |