Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability PJM Brouwer, TG Caniels, K van der Straten, JL Snitselaar, Y Aldon, ... Science 369 (6504), 643-650, 2020 | 1185 | 2020 |
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients D Geers, MC Shamier, S Bogers, G den Hartog, L Gommers, ... Science immunology 6 (59), eabj1750, 2021 | 531 | 2021 |
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity H Liu, NC Wu, M Yuan, S Bangaru, JL Torres, TG Caniels, ... Immunity, 2020 | 211 | 2020 |
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ... Science translational medicine 13 (596), eabf8654, 2021 | 173 | 2021 |
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection PJM Brouwer, M Brinkkemper, P Maisonnasse, N Dereuddre-Bosquet, ... Cell 184 (5), 1188-1200. e19, 2021 | 158 | 2021 |
An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain NC Wu, M Yuan, H Liu, CCD Lee, X Zhu, S Bangaru, JL Torres, ... Cell Reports 33 (3), 108274, 2020 | 155 | 2020 |
Emerging SARS-CoV-2 variants of concern evade humoral immune responses from infection and vaccination TG Caniels, I Bontjer, K van der Straten, M Poniman, JA Burger, ... Science Advances 7 (36), eabj5365, 2021 | 97 | 2021 |
Antibody responses against SARS-CoV-2 variants induced by four different SARS-CoV-2 vaccines in health care workers in the Netherlands: A prospective cohort study MJ van Gils, A Lavell, K van der Straten, B Appelman, I Bontjer, ... PLoS medicine 19 (5), e1003991, 2022 | 72 | 2022 |
Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron K van der Straten, D Guerra, MJ van Gils, I Bontjer, TG Caniels, ... Immunity 55 (9), 1725-1731. e4, 2022 | 70 | 2022 |
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses W Hoepel, HJ Chen, S Allahverdiyeva, X Manz, J Aman, ... BioRxiv, 2020.07. 13.190140, 2020 | 58 | 2020 |
Mapping the antigenic diversification of SARS-CoV-2 K van der Straten, D Guerra, MJ van Gils, I Bontjer, TG Caniels, ... MedRxiv, 2022.01. 03.21268582, 2022 | 57 | 2022 |
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models P Maisonnasse, Y Aldon, A Marc, R Marlin, N Dereuddre-Bosquet, ... Nature communications 12 (1), 6097, 2021 | 46 | 2021 |
A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike M Claireaux, TG Caniels, M de Gast, J Han, D Guerra, G Kerster, ... Nature communications 13 (1), 4539, 2022 | 33 | 2022 |
Human milk antibodies against SARS-CoV-2: a longitudinal follow-up study HG Juncker, M Romijn, VN Loth, TG Caniels, CJM de Groot, D Pajkrt, ... Journal of Human Lactation 37 (3), 485-491, 2021 | 26 | 2021 |
Four SARS-CoV-2 vaccines induce quantitatively different antibody responses against SARS-CoV-2 variants MJ van Gils, AHA Lavell, K van der Straten, B Appelman, I Bontjer, ... | 25* | 2021 |
A single-shot adenoviral vaccine provides hemagglutinin stalk-mediated protection against heterosubtypic influenza challenge in mice CM Bliss, AW Freyn, TG Caniels, VH Leyva-Grado, R Nachbagauer, ... Molecular Therapy 30 (5), 2024-2047, 2022 | 20 | 2022 |
A single mRNA vaccine dose in COVID-19 patients boosts neutralizing antibodies against SARS-CoV-2 and variants of concern MJ van Gils, HDG van Willigen, E Wynberg, AX Han, K van der Straten, ... Cell Reports Medicine 3 (1), 2022 | 20 | 2022 |
Probing affinity, avidity, anticooperativity, and competition in antibody and receptor binding to the SARS-CoV-2 spike by single particle mass analyses V Yin, SH Lai, TG Caniels, PJM Brouwer, M Brinkkemper, Y Aldon, H Liu, ... ACS central science 7 (11), 1863-1873, 2021 | 19 | 2021 |
Single nucleotide polymorphisms of the high affinity IgG receptor FcγRI reduce immune complex binding and downstream effector functions AM Brandsma, T Ten Broeke, E Van Dueren Den Hollander, TG Caniels, ... The Journal of Immunology 199 (7), 2432-2439, 2017 | 18 | 2017 |
A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern M Brinkkemper, PJM Brouwer, P Maisonnasse, M Grobben, TG Caniels, ... npj Vaccines 6 (1), 146, 2021 | 15 | 2021 |