| Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors J Rathjen, JA Lake, MD Bettess, JM Washington, G Chapman, ... Journal of cell Science 112 (5), 601-612, 1999 | 406 | 1999 |
| Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation C Dahlqvist, A Blokzijl, G Chapman, A Falk, K Dannaeus, CF Ibâñez, ... Oxford University Press for The Company of Biologists Limited 130 (24), 6089 …, 2003 | 307 | 2003 |
| Notch signaling in development and disease EM Hansson, U Lendahl, G Chapman Seminars in cancer biology 14 (5), 320-328, 2004 | 303 | 2004 |
| Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype DB Sparrow, G Chapman, MA Wouters, NV Whittock, S Ellard, D Fatkin, ... The American Journal of Human Genetics 78 (1), 28-37, 2006 | 267 | 2006 |
| NAD deficiency, congenital malformations, and niacin supplementation H Shi, A Enriquez, M Rapadas, EMMA Martin, R Wang, J Moreau, CK Lim, ... New England Journal of Medicine 377 (6), 544-552, 2017 | 237 | 2017 |
| A mechanism for gene-environment interaction in the etiology of congenital scoliosis DB Sparrow, G Chapman, AJ Smith, MZ Mattar, JA Major, VC O'Reilly, ... Cell 149 (2), 295-306, 2012 | 236 | 2012 |
| Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis G Chapman, DB Sparrow, E Kremmer, SL Dunwoodie Human molecular genetics 20 (5), 905-916, 2011 | 232 | 2011 |
| Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo I Geffers, K Serth, G Chapman, R Jaekel, K Schuster-Gossler, R Cordes, ... The Journal of cell biology 178 (3), 465-476, 2007 | 211 | 2007 |
| A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling H Karlström, P Beatus, K Dannaeus, G Chapman, U Lendahl, J Lundkvist Proceedings of the National Academy of Sciences 99 (26), 17119-17124, 2002 | 147 | 2002 |
| High levels of Notch signaling down-regulate Numb and Numblike G Chapman, L Liu, C Sahlgren, C Dahlqvist, U Lendahl The Journal of cell biology 175 (4), 535-540, 2006 | 103 | 2006 |
| A screening approach to identify clinically actionable variants causing congenital heart disease in exome data JO Szot, H Cuny, GM Blue, DT Humphreys, E Ip, K Harrison, GF Sholler, ... Circulation: Genomic and Precision Medicine 11 (3), e001978, 2018 | 81 | 2018 |
| Notch4 reveals a novel mechanism regulating Notch signal transduction AC James, JO Szot, K Iyer, JA Major, SE Pursglove, G Chapman, ... Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1843 (7), 1272-1284, 2014 | 74 | 2014 |
| Identification of clinically actionable variants from genome sequencing of families with congenital heart disease D Alankarage, E Ip, JO Szot, J Munro, GM Blue, K Harrison, H Cuny, ... Genetics in Medicine 21 (5), 1111-1120, 2019 | 73 | 2019 |
| NKX2-5 mutations causative for congenital heart disease retain functionality and are directed to hundreds of targets R Bouveret, AJ Waardenberg, N Schonrock, M Ramialison, T Doan, ... elife 4, e06942, 2015 | 70 | 2015 |
| A cell autonomous role for the Notch ligand Delta‐like 3 in αβ T‐cell development GF Hoyne, G Chapman, Y Sontani, SE Pursglove, SL Dunwoodie Immunology and cell biology 89 (6), 696-705, 2011 | 64 | 2011 |
| CRTR-1, a developmentally regulated transcriptional repressor related to the CP2 family of transcription factors S Rodda, S Sharma, M Scherer, G Chapman, P Rathjen Journal of Biological Chemistry 276 (5), 3324-3332, 2001 | 58 | 2001 |
| The mouse homeobox Gene, Gbx2: Genomic organization and expression in pluripotent cellsin vitroandin vivo G Chapman, JL Remiszewski, GC Webb, TC Schulz, CDK Bottema, ... Genomics 46 (2), 223-233, 1997 | 58 | 1997 |
| Loss of Cited2 causes congenital heart disease by perturbing left–right patterning of the body axis K Lopes Floro, ST Artap, JI Preis, D Fatkin, G Chapman, MB Furtado, ... Human molecular genetics 20 (6), 1097-1110, 2011 | 57 | 2011 |
| Gene-environment interaction impacts on heart development and embryo survival JLM Moreau, S Kesteven, EMMA Martin, KS Lau, MX Yam, VC O'Reilly, ... Development 146 (4), dev172957, 2019 | 53 | 2019 |
| Gestational stress induces the unfolded protein response, resulting in heart defects H Shi, VC O'Reilly, JLM Moreau, TR Bewes, MX Yam, BE Chapman, ... Development 143 (14), 2561-2572, 2016 | 51 | 2016 |
