The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death I Livneh, V Cohen-Kaplan, C Cohen-Rosenzweig, N Avni, A Ciechanover Cell research 26 (8), 869-885, 2016 | 375 | 2016 |
Processing and activation of latent heparanase occurs in lysosomes A Zetser, F Levy-Adam, V Kaplan, S Gingis-Velitski, Y Bashenko, ... Journal of cell science 117 (11), 2249-2258, 2004 | 256 | 2004 |
p62-and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome V Cohen-Kaplan, I Livneh, N Avni, B Fabre, T Ziv, YT Kwon, ... Proceedings of the National Academy of Sciences 113 (47), E7490-E7499, 2016 | 252 | 2016 |
Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans S Gingis-Velitski, A Zetser, V Kaplan, O Ben-Zaken, E Cohen, ... Journal of Biological Chemistry 279 (42), 44084-44092, 2004 | 238 | 2004 |
Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis U Barash, V Cohen‐Kaplan, I Dowek, RD Sanderson, N Ilan, I Vlodavsky The FEBS journal 277 (19), 3890-3903, 2010 | 211 | 2010 |
The ubiquitin-proteasome system and autophagy: Coordinated and independent activities V Cohen-Kaplan, I Livneh, N Avni, C Cohen-Rosenzweig, A Ciechanover The international journal of biochemistry & cell biology 79, 403-418, 2016 | 190 | 2016 |
Heparanase 2 interacts with heparan sulfate with high affinity and inhibits heparanase activity F Levy-Adam, S Feld, V Cohen-Kaplan, A Shteingauz, M Gross, G Arvatz, ... Journal of Biological Chemistry 285 (36), 28010-28019, 2010 | 159 | 2010 |
Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression M Blich, A Golan, G Arvatz, A Sebbag, I Shafat, E Sabo, V Cohen-Kaplan, ... Arteriosclerosis, thrombosis, and vascular biology 33 (2), e56-e65, 2013 | 148 | 2013 |
Heparanase induces VEGF C and facilitates tumor lymphangiogenesis V Cohen‐Kaplan, I Naroditsky, A Zetser, N Ilan, I Vlodavsky, I Doweck International journal of cancer 123 (11), 2566-2573, 2008 | 137 | 2008 |
KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth Y Kravtsova-Ivantsiv, I Shomer, V Cohen-Kaplan, B Snijder, ... Cell 161 (2), 333-347, 2015 | 123 | 2015 |
Heparanase localization and expression by head and neck cancer: correlation with tumor progression and patient survival I Doweck, V Kaplan-Cohen, I Naroditsky, E Sabo, N Ilan, I Vlodavsky Neoplasia 8 (12), 1055-1061, 2006 | 114 | 2006 |
Structure-function approach identifies a COOH-terminal domain that mediates heparanase signaling L Fux, N Feibish, V Cohen-Kaplan, S Gingis-Velitski, S Feld, C Geffen, ... Cancer research 69 (5), 1758-1767, 2009 | 110 | 2009 |
Heparanase augments epidermal growth factor receptor phosphorylation: correlation with head and neck tumor progression V Cohen-Kaplan, I Doweck, I Naroditsky, I Vlodavsky, N Ilan Cancer research 68 (24), 10077-10085, 2008 | 107 | 2008 |
Heparanase Expression in Malignant Salivary Gl, Tumors Inversely Correlates with Long-Term Survival O Ben-Izhak, V Kaplan-Cohen, N Ilan, S Gan, I Vlodavsky, R Nagler Neoplasia 8 (10), 879-884, 2006 | 63 | 2006 |
Heparanase induces signal transducer and activator of transcription (STAT) protein phosphorylation: preclinical and clinical significance in head and neck cancer V Cohen-Kaplan, J Jrbashyan, Y Yanir, I Naroditsky, O Ben-Izhak, N Ilan, ... Journal of Biological Chemistry 287 (9), 6668-6678, 2012 | 61 | 2012 |
Heparanase expression in nasopharyngeal carcinoma inversely correlates with patient survival G Bar‐Sela, V Kaplan‐Cohen, N Ilan, I Vlodavsky, O Ben‐Izhak Histopathology 49 (2), 188-193, 2006 | 58 | 2006 |
p62-containing, proteolytically active nuclear condensates, increase the efficiency of the ubiquitin–proteasome system A Fu, V Cohen-Kaplan, N Avni, I Livneh, A Ciechanover Proceedings of the National Academy of Sciences 118 (33), e2107321118, 2021 | 52 | 2021 |
Spatial and temporal heparanase expression in colon mucosa throughout the adenoma-carcinoma sequence V Doviner, B Maly, V Kaplan, S Gingis-Velitski, N Ilan, I Vlodavsky, ... Modern pathology 19 (6), 878-888, 2006 | 52 | 2006 |
p62 at the crossroad of the ubiquitin-proteasome system and autophagy V Cohen-Kaplan, A Ciechanover, I Livneh Oncotarget 7 (51), 83833, 2016 | 49 | 2016 |
Bax/Mcl-1 balance affects neutrophil survival in intermittent hypoxia and obstructive sleep apnea: effects of p38MAPK and ERK1/2 signaling L Dyugovskaya, A Polyakov, V Cohen-Kaplan, P Lavie, L Lavie Journal of translational medicine 10, 1-13, 2012 | 49 | 2012 |