Assessment of 2q23. 1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder ME Talkowski, SV Mullegama, JA Rosenfeld, BWM Van Bon, Y Shen, ... The American Journal of human genetics 89 (4), 551-563, 2011 | 243 | 2011 |
Mutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans Y Wu, AC Arai, G Rumbaugh, AK Srivastava, G Turner, T Hayashi, ... Proceedings of the National Academy of Sciences 104 (46), 18163-18168, 2007 | 136 | 2007 |
Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis X Liao, R Zhang, Y Lu, DA Prosdocimo, P Sangwung, L Zhang, G Zhou, ... The Journal of clinical investigation 125 (9), 3461-3476, 2015 | 135 | 2015 |
Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism DA Prosdocimo, P Anand, X Liao, H Zhu, S Shelkay, P Artero-Calderon, ... Journal of Biological Chemistry 289 (9), 5914-5924, 2014 | 131 | 2014 |
Circadian control of bile acid synthesis by a KLF15-Fgf15 axis S Han, R Zhang, R Jain, H Shi, L Zhang, G Zhou, P Sangwung, D Tugal, ... Nature communications 6 (1), 7231, 2015 | 96 | 2015 |
KLF15 establishes the landscape of diurnal expression in the heart L Zhang, DA Prosdocimo, X Bai, C Fu, R Zhang, F Campbell, X Liao, ... Cell reports 13 (11), 2368-2375, 2015 | 94 | 2015 |
REV-ERBα ameliorates heart failure through transcription repression L Zhang, R Zhang, CL Tien, RE Chan, K Sugi, C Fu, AC Griffin, Y Shen, ... JCI insight 2 (17), 2017 | 74 | 2017 |
Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure R Zhang, Y Shen, L Zhou, P Sangwung, H Fujioka, L Zhang, X Liao Journal of molecular and cellular cardiology 112, 64-73, 2017 | 73 | 2017 |
KLF15 and PPARα Cooperate to Regulate Cardiomyocyte Lipid Gene Expression and Oxidation DA Prosdocimo, JE John, L Zhang, ES Efraim, R Zhang, X Liao, MK Jain PPAR research 2015 (1), 201625, 2015 | 73 | 2015 |
Myocardial Rev-erb–mediated diurnal metabolic rhythm and obesity paradox S Song, CL Tien, H Cui, P Basil, N Zhu, Y Gong, W Li, H Li, Q Fan, ... Circulation 145 (6), 448-464, 2022 | 56 | 2022 |
Functional Variants in DPYSL2 Sequence Increase Risk of Schizophrenia and Suggest a Link to mTOR Signaling Y Liu, X Pham, L Zhang, P Chen, G Burzynski, DM McGaughey, S He, ... G3: Genes, Genomes, Genetics 5 (1), 61-72, 2015 | 49 | 2015 |
Circadian regulation of cardiac metabolism L Zhang, MK Jain The Journal of Clinical Investigation 131 (15), 2021 | 39 | 2021 |
Kruppel-like factor 15 regulates the circadian susceptibility to ischemia reperfusion injury in the heart L Li, H Li, CL Tien, MK Jain, L Zhang Circulation 141 (17), 1427-1429, 2020 | 31 | 2020 |
A microdeletion in Xp11. 3 accounts for co‐segregation of retinitis pigmentosa and mental retardation in a large kindred L Zhang, T Wang, AF Wright, M Suri, CE Schwartz, RE Stevenson, D Valle American Journal of Medical Genetics Part A 140 (4), 349-357, 2006 | 31 | 2006 |
NAD+ Metabolism as an Emerging Therapeutic Target for Cardiovascular Diseases Associated With Sudden Cardiac Death W Xu, L Li, L Zhang Frontiers in physiology 11, 901, 2020 | 30 | 2020 |
Coordination of cardiac rhythmic output and circadian metabolic regulation in the heart PN Hsieh, L Zhang, MK Jain Cellular and molecular life sciences 75, 403-416, 2018 | 27 | 2018 |
Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammation DR Sweet, NT Vasudevan, L Fan, CE Booth, KS Keerthy, X Liao, ... Nature Communications 11 (1), 5872, 2020 | 25 | 2020 |
Cardiac crises: cardiac arrhythmias and cardiomyopathy during TANGO2 deficiency related metabolic crises CY Miyake, EJ Lay, CM Beach, SR Ceresnak, CM Delauz, TS Howard, ... Heart Rhythm 19 (10), 1673-1681, 2022 | 24 | 2022 |
Natural history of TANGO2 deficiency disorder: baseline assessment of 73 patients CY Miyake, EJ Lay, C Soler-Alfonso, KE Glinton, KM Houck, M Tosur, ... Genetics in Medicine 25 (4), 100352, 2023 | 23 | 2023 |
X chromosome cDNA microarray screening identifies a functional PLP2 promoter polymorphism enriched in patients with X-linked mental retardation L Zhang, C Jie, C Obie, F Abidi, CE Schwartz, RE Stevenson, D Valle, ... Genome research 17 (5), 641-648, 2007 | 23 | 2007 |