A protein kinase involved in the regulation of inflammatory cytokine biosynthesis JC Lee, JT Laydon, PC McDonnell, TF Gallagher, S Kumar, D Green, ... Nature 372 (6508), 739-746, 1994 | 4143 | 1994 |
p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases S Kumar, J Boehm, JC Lee Nature reviews Drug discovery 2 (9), 717-726, 2003 | 1556 | 2003 |
Experimental evidence of hyperbolic heat conduction in processed meat K Mitra, S Kumar, A Vedevarz, MK Moallemi | 801 | 1995 |
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site PR Young, MM McLaughlin, S Kumar, S Kassis, ML Doyle, D McNulty, ... Journal of Biological Chemistry 272 (18), 12116-12121, 1997 | 743 | 1997 |
Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles S Kumar, PC McDonnell, RJ Gum, AT Hand, JC Lee, PR Young Biochemical and biophysical research communications 235 (3), 533-538, 1997 | 678 | 1997 |
Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion XL Ma, S Kumar, F Gao, CS Louden, BL Lopez, TA Christopher, C Wang, ... Circulation 99 (13), 1685-1691, 1999 | 671 | 1999 |
Inhibition of p38 MAP kinase as a therapeutic strategy JC Lee, S Kumar, DE Griswold, DC Underwood, BJ Votta, JL Adams Immunopharmacology 47 (2-3), 185-201, 2000 | 637 | 2000 |
Inhibition of extracellular signal–regulated kinase enhances ischemia/reoxygenation–induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in … TL Yue, C Wang, JL Gu, XL Ma, S Kumar, JC Lee, GZ Feuerstein, ... Circulation research 86 (6), 692-699, 2000 | 549 | 2000 |
p38 mitogen-activated protein kinase inhibitors—mechanisms and therapeutic potentials JC Lee, S Kassis, S Kumar, A Badger, JL Adams Pharmacology & therapeutics 82 (2-3), 389-397, 1999 | 497 | 1999 |
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase MM McLaughlin, S Kumar, PC McDonnell, S Van Horn, JC Lee, GP Livi, ... Journal of Biological Chemistry 271 (14), 8488-8492, 1996 | 483 | 1996 |
Identification and initial characterization of four novel members of the interleukin-1 family S Kumar, PC McDonnell, R Lehr, L Tierney, MN Tzimas, DE Griswold, ... Journal of Biological Chemistry 275 (14), 10308-10314, 2000 | 464 | 2000 |
Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by … TL Yue, XL Ma, X Wang, AM Romanic, G Liu, C Louden, JL Gu, S Kumar, ... Circulation research 82 (2), 166-174, 1998 | 387 | 1998 |
Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes MN Phan, HA Leddy, BJ Votta, S Kumar, DS Levy, DB Lipshutz, SH Lee, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 350 | 2009 |
Inhibition of p38 mitogen‐activated protein kinase provides neuroprotection in cerebral focal ischemia FC Barone, EA Irving, AM Ray, JC Lee, S Kassis, S Kumar, AM Badger, ... Medicinal research reviews 21 (2), 129-145, 2001 | 346 | 2001 |
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase S Kumar, MS Jiang, JL Adams, JC Lee Biochemical and biophysical research communications 263 (3), 825-831, 1999 | 346 | 1999 |
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket RJ Gum, MM McLaughlin, S Kumar, Z Wang, MJ Bower, JC Lee, ... Journal of Biological Chemistry 273 (25), 15605-15610, 1998 | 342 | 1998 |
Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-γ production S Kumar, CR Hanning, MR Brigham-Burke, DJ Rieman, R Lehr, ... Cytokine 18 (2), 61-71, 2002 | 337 | 2002 |
A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity P Bufler, T Azam, F Gamboni-Robertson, LL Reznikov, S Kumar, ... Proceedings of the National Academy of Sciences 99 (21), 13723-13728, 2002 | 309 | 2002 |
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia FC Barone, EA Irving, AM Ray, JC Lee, S Kassis, S Kumar, AM Badger, ... Journal of Pharmacology and Experimental Therapeutics 296 (2), 312-321, 2001 | 291 | 2001 |
Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase TF Gallagher, GL Seibel, S Kassis, JT Laydon, MJ Blumenthal, JC Lee, ... Bioorganic & Medicinal Chemistry 5 (1), 49-64, 1997 | 289 | 1997 |