| Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome Z Han, C Chen, A Christiansen, S Ji, Q Lin, C Anumonwo, C Liu, ... Science translational medicine 12 (558), eaaz6100, 2020 | 244 | 2020 |
| A cog in cognition: how the α7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits SC Leiser, MR Bowlby, TA Comery, J Dunlop Pharmacology & therapeutics 122 (3), 302-311, 2009 | 207 | 2009 |
| Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function E Dale, AL Pehrson, T Jeyarajah, Y Li, SC Leiser, G Smagin, CK Olsen, ... CNS spectrums 21 (2), 143-161, 2016 | 162 | 2016 |
| Responses of trigeminal ganglion neurons during natural whisking behaviors in the awake rat SC Leiser, KA Moxon Neuron 53 (1), 117-133, 2007 | 160 | 2007 |
| Aligning strategies for using EEG as a surrogate biomarker: a review of preclinical and clinical research SC Leiser, J Dunlop, MR Bowlby, DM Devilbiss Biochemical pharmacology 81 (12), 1408-1421, 2011 | 156 | 2011 |
| Treatment of cognitive dysfunction in major depressive disorder—a review of the preclinical evidence for efficacy of selective serotonin reuptake inhibitors, serotonin … AL Pehrson, SC Leiser, M Gulinello, E Dale, Y Li, JA Waller, C Sanchez European journal of pharmacology 753, 19-31, 2015 | 154 | 2015 |
| Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease JT Brown, J Chin, SC Leiser, MN Pangalos, AD Randall Neurobiology of aging 32 (11), 2109. e1-2109. e14, 2011 | 125 | 2011 |
| Serotonergic regulation of prefrontal cortical circuitries involved in cognitive processing: a review of individual 5-HT receptor mechanisms and concerted effects of 5-HT … SC Leiser, Y Li, AL Pehrson, E Dale, G Smagin, C Sanchez ACS chemical neuroscience 6 (7), 970-986, 2015 | 119 | 2015 |
| Predator stress engages corticotropin-releasing factor and opioid systems to alter the operating mode of locus coeruleus norepinephrine neurons AL Curtis, SC Leiser, K Snyder, RJ Valentino Neuropharmacology 62 (4), 1737-1745, 2012 | 118 | 2012 |
| Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease BF Corbett, SC Leiser, HP Ling, R Nagy, N Breysse, X Zhang, A Hazra, ... Journal of Neuroscience 33 (16), 7020-7026, 2013 | 107 | 2013 |
| Vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus E Dale, H Zhang, SC Leiser, Y Xiao, D Lu, CR Yang, N Plath, C Sanchez Journal of psychopharmacology 28 (10), 891-902, 2014 | 105 | 2014 |
| Impact of state of arousal and stress neuropeptides on urodynamic function in freely moving rats DA Kiddoo, RJ Valentino, S Zderic, A Ganesh, SC Leiser, L Hale, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2006 | 73 | 2006 |
| Relationship between physiological response type (RA and SA) and vibrissal receptive field of neurons within the rat trigeminal ganglion SC Leiser, KA Moxon Journal of neurophysiology 95 (5), 3129-3145, 2006 | 73 | 2006 |
| Multimodal antidepressant vortioxetine increases frontal cortical oscillations unlike escitalopram and duloxetine–a quantitative EEG study in rats SC Leiser, AL Pehrson, PJ Robichaud, C Sanchez British journal of pharmacology 171 (18), 4255-4272, 2014 | 61 | 2014 |
| Impact of overactive bladder on the brain: central sequelae of a visceral pathology E Rickenbacher, MA Baez, L Hale, SC Leiser, SA Zderic, RJ Valentino Proceedings of the national academy of sciences 105 (30), 10589-10594, 2008 | 50 | 2008 |
| Aβ-accelerated neurodegeneration caused by Alzheimer’s-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice LK Cuddy, D Prokopenko, EP Cunningham, R Brimberry, P Song, ... Science translational medicine 12 (563), eaaz2541, 2020 | 33 | 2020 |
| Novel brain permeant mTORC1/2 inhibitors are as efficacious as rapamycin or everolimus in mouse models of acquired partial epilepsy and tuberous sclerosis complex W Theilmann, B Gericke, A Schidlitzki, SMM Anjum, S Borsdorf, T Harries, ... Neuropharmacology 180, 108297, 2020 | 24 | 2020 |
| The 5-HT6 receptor antagonist idalopirdine potentiates the effects of donepezil on gamma oscillations in the frontal cortex of anesthetized and awake rats without affecting … M Amat-Foraster, SC Leiser, KF Herrik, N Richard, C Agerskov, ... Neuropharmacology 113, 45-59, 2017 | 24 | 2017 |
| Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 … SC Leiser, D Iglesias-Bregna, L Westrich, AL Pehrson, C Sanchez Journal of Psychopharmacology 29 (10), 1092-1105, 2015 | 24 | 2015 |
| Can pharmaco-electroencephalography help improve survival of central nervous system drugs in early clinical development? FJ Wilson, SC Leiser, M Ivarsson, SR Christensen, JF Bastlund Drug Discovery Today 19 (3), 282-288, 2014 | 23 | 2014 |
