| scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy JK Ocasio, B Babcock, D Malawsky, SJ Weir, L Loo, JM Simon, MJ Zylka, ... Nature communications 10 (1), 5829, 2019 | 94 | 2019 |
| Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma KA Riemondy, S Venkataraman, N Willard, A Nellan, B Sanford, ... Neuro-oncology 24 (2), 273-286, 2022 | 68 | 2022 |
| Fine-scale population structure and demographic history of British Pakistanis E Arciero, SA Dogra, DS Malawsky, M Mezzavilla, T Tsismentzoglou, ... Nature Communications 12 (1), 7189, 2021 | 30 | 2021 |
| Genetic identification of a population of noradrenergic neurons implicated in attenuation of stress-related responses YW Chen, M Das, EA Oyarzabal, Q Cheng, NW Plummer, KG Smith, ... Molecular psychiatry 24 (5), 710-725, 2019 | 24 | 2019 |
| Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq–guided combination with sapanisertib C Lim, T Dismuke, D Malawsky, JD Ramsey, D Hwang, VL Godfrey, ... Science advances 8 (4), eabl5838, 2022 | 21 | 2022 |
| Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile DS Malawsky, SJ Weir, JK Ocasio, B Babcock, T Dismuke, AH Cleveland, ... Communications biology 4 (1), 616, 2021 | 15 | 2021 |
| Influence of autozygosity on common disease risk across the phenotypic spectrum DS Malawsky, E van Walree, BM Jacobs, TH Heng, QQ Huang, AH Sabir, ... Cell 186 (21), 4514-4527. e14, 2023 | 12 | 2023 |
| OLIG2 is a determinant for the relapse of MYC-amplified medulloblastoma Z Xu, N Murad, DS Malawsky, R Tao, S Rivero-Hinojosa, D Holdhof, ... Clinical Cancer Research, 2022 | 7 | 2022 |
| Spatiotemporal analysis of induced neural stem cell therapy to overcome advanced glioblastoma recurrence AB Satterlee, DE Dunn, A Valdivia, D Malawsky, A Buckley, T Gershon, ... Molecular Therapy-Oncolytics 26, 49-62, 2022 | 4 | 2022 |
| LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and associates with viral infections EA Gomez, R De Matteis, P Udomjarumanee, S Akhtar, M Anwar, ... Blood, 2024 | 1 | 2024 |
| Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells DS Malawsky, T Dismuke, H Liu, E Castellino, J Brenman, B Dasgupta, ... Iscience 26 (12), 2023 | 1 | 2023 |
| Preventing recurrence in Sonic Hedgehog Subgroup Medulloblastoma using the OLIG2 inhibitor CT-179 Y Li, C Lim, T Dismuke, DS Malawsky, S Oasa, ZC Bruce, C Offenhäuser, ... Research Square, 2023 | 1 | 2023 |
| PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth AH Cleveland, D Malawsky, M Churiwal, C Rodriguez, F Reed, ... Acta Neuropathologica Communications 11 (1), 8, 2023 | 1 | 2023 |
| Federated analysis of the contribution of recessive coding variants to 29,745 developmental disorder patients from diverse populations VK Chundru, Z Zhang, K Walter, S Lindsay, P Danecek, RY Eberhardt, ... medRxiv, 2023.07. 24.23293070, 2023 | 1 | 2023 |
| Mortality, morbidity and educational outcomes in children of consanguineous parents in the Born in Bradford cohort N Small, B Kelly, DS Malawsky, R Lodh, S Oddie, J Wright Wellcome Open Research 9, 319, 2024 | | 2024 |
| Widespread recessive effects on common diseases in a cohort of 44,000 British Pakistanis and Bangladeshis with high autozygosity TH Heng, K Walter, QQ Huang, J Karjalainen, MJ Daly, HO Heyne, ... medRxiv, 2024.04. 03.24305256, 2024 | | 2024 |
| Dissecting the contribution of common variants to risk of rare neurodevelopmental conditions QQ Huang, EM Wigdor, P Campbell, DS Malawsky, KE Samocha, ... medRxiv, 2024.03. 05.24303772, 2024 | | 2024 |
Timothy GershonUniversity of North Carolina at Chapel Hill在 neurology.unc.edu 的电子邮件经过验证
