CAR-T cells hit the tumor microenvironment: strategies to overcome tumor escape A Rodriguez-Garcia, A Palazon, E Noguera-Ortega, DJ Powell Jr, ... Frontiers in immunology 11, 1109, 2020 | 223 | 2020 |
CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy A Rodriguez-Garcia, RC Lynn, M Poussin, MA Eiva, LC Shaw, ... Nature communications 12 (1), 877, 2021 | 196 | 2021 |
Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression A Rodríguez-García, M Giménez-Alejandre, JJ Rojas, R Moreno, ... Clinical Cancer Research 21 (6), 1406-1418, 2015 | 117 | 2015 |
VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects M Bazan-Peregrino, R Garcia-Carbonero, B Laquente, R Álvarez, ... Journal for ImmunoTherapy of Cancer 9 (11), 2021 | 53 | 2021 |
Quantitative control of gene-engineered T-cell activity through the covalent attachment of targeting ligands to a universal immune receptor NG Minutolo, P Sharma, M Poussin, LC Shaw, DP Brown, EE Hollander, ... Journal of the American Chemical Society 142 (14), 6554-6568, 2020 | 47 | 2020 |
A pRb-responsive, RGD-modified, and hyaluronidase-armed canine oncolytic adenovirus for application in veterinary oncology E Laborda, C Puig-Saus, A Rodriguez-García, R Moreno, M Cascalló, ... Molecular Therapy 22 (5), 986-998, 2014 | 47 | 2014 |
Protein carbonylation and lipid peroxidation in hematological malignancies A Rodríguez-García, R García-Vicente, ML Morales, A Ortiz-Ruiz, ... Antioxidants 9 (12), 1212, 2020 | 44 | 2020 |
An autologous humanized patient-derived-xenograft platform to evaluate immunotherapy in ovarian cancer SB Gitto, H Kim, S Rafail, DK Omran, S Medvedev, Y Kinose, ... Gynecologic Oncology 156 (1), 222-232, 2020 | 43 | 2020 |
Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo XJ Xu, DG Song, M Poussin, Q Ye, P Sharma, A Rodríguez-García, ... Oncotarget 7 (50), 82354, 2016 | 42 | 2016 |
Epigenetic state determines inflammatory sensing in neuroblastoma AJ Wolpaw, LD Grossmann, JL Dessau, MM Dong, BJ Aaron, PA Brafford, ... Proceedings of the National Academy of Sciences 119 (6), e2102358119, 2022 | 35 | 2022 |
CAR T cells targeting MISIIR for the treatment of ovarian cancer and other gynecologic malignancies A Rodriguez-Garcia, P Sharma, M Poussin, AC Boesteanu, NG Minutolo, ... Molecular Therapy 28 (2), 548-560, 2020 | 32 | 2020 |
MEK inhibition enhances the response to tyrosine kinase inhibitors in acute myeloid leukemia ML Morales, A Arenas, A Ortiz-Ruiz, A Leivas, I Rapado, ... Scientific reports 9 (1), 18630, 2019 | 32 | 2019 |
T-cell target antigens across major gynecologic cancers A Rodriguez-Garcia, NG Minutolo, JM Robinson, DJ Powell Gynecologic Oncology 145 (3), 426-435, 2017 | 29 | 2017 |
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety A Smole, A Benton, MA Poussin, MA Eiva, C Mezzanotte, B Camisa, ... Cancer Cell 40 (12), 1470-1487. e7, 2022 | 22 | 2022 |
Insertion of exogenous epitopes in the E3-19K of oncolytic adenoviruses to enhance TAP-independent presentation and immunogenicity A Rodríguez-García, E Svensson, R Gil-Hoyos, CA Fajardo, LA Rojas, ... Gene therapy 22 (7), 596-601, 2015 | 21 | 2015 |
Time 2EVOLVE: predicting efficacy of engineered T-cells–how far is the bench from the bedside? S Guedan, M Luu, D Ammar, P Barbao, C Bonini, P Bousso, CJ Buchholz, ... Journal for Immunotherapy of Cancer 10 (5), 2022 | 19 | 2022 |
Folate receptor beta as a direct and indirect target for antibody-based cancer immunotherapy AG Roy, JM Robinson, P Sharma, A Rodriguez-Garcia, MA Poussin, ... International Journal of Molecular Sciences 22 (11), 5572, 2021 | 14 | 2021 |
Efficacy of antiviral treatment in hepatitis C virus (HCV)-driven monoclonal gammopathies including myeloma A Rodríguez-García, M Linares, ML Morales, S Allain-Maillet, ... Frontiers in Immunology 12, 797209, 2022 | 11 | 2022 |
The combination of i-leader truncation and gemcitabine improves oncolytic adenovirus efficacy in an immunocompetent model C Puig-Saus, E Laborda, A Rodriguez-Garcia, M Cascallo, R Moreno, ... Cancer gene therapy 21 (2), 68-73, 2014 | 11 | 2014 |
Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain J Nong, PM Glassman, JW Myerson, V Zuluaga-Ramirez, ... ACS nano 17 (14), 13121-13136, 2023 | 10 | 2023 |