Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655 SY Gerdes, MD Scholle, JW Campbell, G Balazsi, E Ravasz, ... Journal of bacteriology 185 (19), 5673-5684, 2003 | 940 | 2003 |
A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner V Schellenberger, C Wang, NC Geething, BJ Spink, A Campbell, W To, ... Nature biotechnology 27 (12), 1186-1190, 2009 | 618 | 2009 |
From genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathways SY Gerdes, MD Scholle, M D'Souza, A Bernal, MV Baev, M Farrell, ... Journal of bacteriology 184 (16), 4555-4572, 2002 | 336 | 2002 |
Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics M Daugherty, B Polanuyer, M Farrell, M Scholle, A Lykidis, ... Journal of Biological Chemistry 277 (24), 21431-21439, 2002 | 282 | 2002 |
Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation ML Kuhn, B Zemaitaitis, LI Hu, A Sahu, D Sorensen, G Minasov, BP Lima, ... PloS one 9 (4), e94816, 2014 | 260 | 2014 |
Methods for production of unstructured recombinant polymers and uses thereof V Schellenberger, WP Stemmer, CW Wang, MD Scholle, M Popkov, ... US Patent 7,846,445, 2010 | 123 | 2010 |
High-throughput screening of small molecule libraries using SAMDI mass spectrometry ZA Gurard-Levin, MD Scholle, AH Eisenberg, M Mrksich ACS combinatorial science 13 (4), 347-350, 2011 | 116 | 2011 |
Molecular recognition properties of FN3 monobodies that bind the Src SH3 domain E Karatan, M Merguerian, Z Han, MD Scholle, S Koide, BK Kay Chemistry & biology 11 (6), 835-844, 2004 | 113 | 2004 |
The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites A AbouElfetouh, ML Kuhn, LI Hu, MD Scholle, DJ Sorensen, AK Sahu, ... Microbiologyopen 4 (1), 66-83, 2015 | 110 | 2015 |
Efficient construction of a large collection of phage-displayed combinatorial peptide libraries MD Scholle, JW Kehoe, BK Kay Combinatorial chemistry & high throughput screening 8 (6), 545-551, 2005 | 77 | 2005 |
Biologically active proteins having increased In Vivo and/or In Vitro stability V Schellenberger, WP Stemmer, CW Wang, MD Scholle, M Popkov, ... US Patent App. 12/634,556, 2010 | 74 | 2010 |
Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose NC Geething, W To, BJ Spink, MD Scholle, C Wang, Y Yin, Y Yao, ... PloS one 5 (4), e10175, 2010 | 74 | 2010 |
Unstructured recombinant polymers and uses thereof V Schellenberger, WP Stemmer, CW Wang, MD Scholle, M Popkov, ... US Patent 7,855,279, 2010 | 71 | 2010 |
In vivo biotinylated proteins as targets for phage-display selection experiments MD Scholle, FR Collart, BK Kay Protein expression and purification 37 (1), 243-252, 2004 | 66 | 2004 |
Mapping protease substrates by using a biotinylated phage substrate library MD Scholle, U Kriplani, A Pabon, K Sishtla, MJ Glucksman, BK Kay Chembiochem 7 (5), 834-838, 2006 | 60 | 2006 |
Discovery of SIRT3 inhibitors using SAMDI mass spectrometry K Patel, J Sherrill, M Mrksich, MD Scholle Journal of biomolecular screening 20 (7), 842-848, 2015 | 59 | 2015 |
Proteinaceous pharmaceuticals and uses thereof W Stemmer, V Schellenberger, M Bader, M Scholle US Patent App. 11/528,927, 2007 | 57 | 2007 |
A high-throughput mass spectrometry assay coupled with redox activity testing reduces artifacts and false positives in lysine demethylase screening TJ Wigle, KK Swinger, JE Campbell, MD Scholle, J Sherrill, EA Admirand, ... Journal of biomolecular screening 20 (6), 810-820, 2015 | 45 | 2015 |
Genetic package and uses thereof WP Stemmer, V Schellenberger, CW Wang, MD Scholle, M Popkov, ... US Patent App. 11/715,300, 2009 | 44 | 2009 |
Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development C Liu, S Boland, MD Scholle, D Bardiot, A Marchand, P Chaltin, LM Blatt, ... Antiviral Research 187, 105020, 2021 | 43 | 2021 |