Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins D Schlam, RD Bagshaw, SA Freeman, RF Collins, T Pawson, GD Fairn, ... Nature communications 6 (1), 8623, 2015 | 231 | 2015 |
Phosphoinositides in phagocytosis and macropinocytosis R Levin, S Grinstein, D Schlam Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 166 | 2015 |
Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages J Canton, D Schlam, C Breuer, M Gütschow, M Glogauer, S Grinstein Nature communications 7 (1), 11284, 2016 | 154 | 2016 |
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes M Bohdanowicz, D Schlam, M Hermansson, D Rizzuti, GD Fairn, ... Molecular biology of the cell 24 (11), 1700-1712, 2013 | 124 | 2013 |
Gliotoxin suppresses macrophage immune function by subverting phosphatidylinositol 3, 4, 5-trisphosphate homeostasis D Schlam, J Canton, M Carreño, H Kopinski, SA Freeman, S Grinstein, ... MBio 7 (2), 10.1128/mbio. 02242-15, 2016 | 66 | 2016 |
Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation D Schlam, M Bohdanowicz, A Chatilialoglu, BE Steinberg, T Ueyama, ... Journal of Biological Chemistry 288 (32), 23090-23104, 2013 | 44 | 2013 |
Chemokine signaling enhances CD36 responsiveness toward oxidized low-density lipoproteins and accelerates foam cell formation HS Wong, V Jaumouille, SA Freeman, SA Doodnauth, D Schlam, ... Cell Reports 14 (12), 2859-2871, 2016 | 34 | 2016 |
Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes D Mukherjee, A Sen, DR Boettner, GD Fairn, D Schlam, ... Journal of cell science 126 (20), 4560-4571, 2013 | 30 | 2013 |
Vascular endothelial cells evade complement‐mediated membrane injury via Weibel‐Palade body mobilization MR Khursigara, D Schlam, DG Noone, V Bruno, CG Ortiz-Sandoval, ... Journal of Thrombosis and Haemostasis 18 (6), 1484-1494, 2020 | 20 | 2020 |
Every day I'm rufflin': Calcium sensing and actin dynamics in the growth factor-independent membrane ruffling of professional phagocytes D Schlam, J Canton Small GTPases 8 (2), 65-70, 2017 | 15 | 2017 |
Screening for Rho GTPase modulators in actin-dependent processes exemplified by phagocytosis D Schlam, S Grinstein, SA Freeman Rho GTPases: Methods and Protocols, 107-127, 2018 | 1 | 2018 |
Functional consequences of complement activation on vascular endothelial cells–Results of a pilot RNA seq study M Riedl, E Jacobs, A Zhou, D Schlam, S Grinstein, C Licht Molecular Immunology 102, 204, 2018 | | 2018 |
ROLE OF VON WILLEBRAND FACTOR (VWF) IN ENDOTHELIAL CELL REPAIR AFTER COMPLEMENT ACTIVATION M Riedl, D Schlam, D Noone, C Licht PEDIATRIC NEPHROLOGY 32 (9), 1677-1677, 2017 | | 2017 |
Role of von Willebrand Factor (VWF) in endothelial cell repair after complement activation M Riedl, D Schlam, D Noone, S Grinstein, C Licht PEDIATRIC NEPHROLOGY 31 (10), 1757-1757, 2016 | | 2016 |
Regulation of Phagocyte Immunity by Lipid Signals D Schlam University of Toronto (Canada), 2016 | | 2016 |
COMPLEMENT ACTIVATION AFFECTS ENDOTHELIAL REPAIR VIA IMPAIRED CELL MIGRATION M Riedl, D Schlam, F Pluthero, W Kahr, C Licht PEDIATRIC NEPHROLOGY 30 (9), 1555-1555, 2015 | | 2015 |
Erratum: Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation (Journal of … D Schlam, M Bohdanowicz, A Chatgilialoglu, BE Steinberg, T Ueyama, ... Journal of Biological Chemistry 289 (8), 4813, 2014 | | 2014 |
Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. D Schlam, M Bohdanowicz, A Chatgilialoglu, BE Steinberg, T Ueyama, ... Journal of Biological Chemistry 289 (8), 4813, 2014 | | 2014 |
Diacylglycerol kinases attenuate phagosomal NOX activation D Schlam, M Bohdanowicz, A Chatilialoglu, BE Steinberg, T Ueyama, ... | | 2013 |