| Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones M Saffarzadeh, C Juenemann, MA Queisser, G Lochnit, G Barreto, ... PloS one 7 (2), e32366, 2012 | 1357 | 2012 |
| miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma FM Kouri, LA Hurley, WL Daniel, ES Day, Y Hua, L Hao, CY Peng, ... Genes & development 29 (7), 732-745, 2015 | 233 | 2015 |
| Hyperglycemia impairs proteasome function by methylglyoxal MA Queisser, D Yao, S Geisler, HP Hammes, G Lochnit, ED Schleicher, ... Diabetes 59 (3), 670-678, 2010 | 221 | 2010 |
| Loss of RAGE in pulmonary fibrosis: molecular relations to functional changes in pulmonary cell types MA Queisser, FM Kouri, M Konigshoff, M Wygrecka, U Schubert, ... American journal of respiratory cell and molecular biology 39 (3), 337-345, 2008 | 157 | 2008 |
| The PROTACtable genome M Schneider, CJ Radoux, A Hercules, D Ochoa, I Dunham, LP Zalmas, ... Nature reviews Drug discovery 20 (10), 789-797, 2021 | 148 | 2021 |
| Discovery and characterisation of highly cooperative FAK‐degrading PROTACs RP Law, J Nunes, C Chung, M Bantscheff, K Buda, H Dai, JP Evans, ... Angewandte Chemie International Edition 60 (43), 23327-23334, 2021 | 70 | 2021 |
| Structural insights into PROTAC-mediated degradation of Bcl-xL C Chung, H Dai, E Fernandez, CP Tinworth, I Churcher, J Cryan, ... ACS Chemical Biology 15 (9), 2316-2323, 2020 | 63 | 2020 |
| Targeting endogenous K-RAS for degradation through the affinity-directed protein missile system S Röth, TJ Macartney, A Konopacka, KH Chan, H Zhou, MA Queisser, ... Cell Chemical Biology 27 (9), 1151-1163. e6, 2020 | 58 | 2020 |
| Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD) J Schulz, D Avci, MA Queisser, A Gutschmidt, LS Dreher, EJ Fenech, ... Journal of Cell Science 130 (19), 3322-3335, 2017 | 57 | 2017 |
| Plasminogen activator inhibitor type 1 inhibits smooth muscle cell proliferation in pulmonary arterial hypertension FM Kouri, MA Queisser, M Königshoff, I Chrobak, KT Preissner, W Seeger, ... The International Journal of Biochemistry & Cell Biology 40 (9), 1872-1882, 2008 | 45 | 2008 |
| HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth MA Queisser, LA Dada, N Deiss-Yehiely, M Angulo, G Zhou, FM Kouri, ... American journal of respiratory and critical care medicine 190 (6), 688-698, 2014 | 38 | 2014 |
| HIF and HOIL-1L–mediated PKCζ degradation stabilizes plasma membrane Na, K-ATPase to protect against hypoxia-induced lung injury ND Magnani, LA Dada, MA Queisser, PL Brazee, LC Welch, KR Anekalla, ... Proceedings of the National Academy of Sciences 114 (47), E10178-E10186, 2017 | 36 | 2017 |
| Antibody-proteolysis targeting chimera conjugate enables selective degradation of receptor-interacting serine/threonine-protein kinase 2 in HER2+ cell lines K Chan, PS Sathyamurthi, MA Queisser, M Mullin, H Shrives, DM Coe, ... Bioconjugate Chemistry 34 (11), 2049-2054, 2023 | 10 | 2023 |
| Targeted protein degradation LL Brayshaw, MM Hann, C Herring, CM Fleites, MA Queisser US Patent 10,683,360, 2020 | 8 | 2020 |
| Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3 S Röth, NM Kocaturk, PS Sathyamurthi, B Carton, M Watt, TJ Macartney, ... Cell Chemical Biology 30 (10), 1261-1276. e7, 2023 | 7 | 2023 |
| Illuminating the druggable genome through patent bioactivity data MP Magariños, A Gaulton, E Félix, T Kiziloren, R Arcila, TI Oprea, ... PeerJ 11, e15153, 2023 | 7 | 2023 |
| Structure-guided design and optimization of covalent VHL-targeted sulfonyl fluoride PROTACs RR Shah, E De Vita, PS Sathyamurthi, D Conole, X Zhang, E Fellows, ... Journal of Medicinal Chemistry 67 (6), 4641-4654, 2024 | 4 | 2024 |
| A phenotypic approach for the identification of new molecules for targeted protein degradation applications P Stacey, H Lithgow, X Lewell, A Konopacka, S Besley, G Green, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (7), 885-895, 2021 | 2 | 2021 |
| Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells PJ Brennan, RE Saunders, M Spanou, M Serafini, L Sun, GP Heger, ... bioRxiv, 2024 | 1 | 2024 |
| Antibody-PROTAC Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 (RIPK2) in HER+ Cell Lines K Chan, PS Sathyamurthi, M Queisser, M Mullin, H Shrives, D Coe, ... | 1 | 2023 |
