Computationally designed libraries for rapid enzyme stabilization HJ Wijma, RJ Floor, PA Jekel, D Baker, SJ Marrink, DB Janssen Protein Engineering, Design & Selection 27 (2), 49-58, 2014 | 286 | 2014 |
Structure-and sequence-analysis inspired engineering of proteins for enhanced thermostability HJ Wijma, RJ Floor, DB Janssen Current opinion in structural biology 23 (4), 588-594, 2013 | 220 | 2013 |
Enantioselective enzymes by computational design and in silico screening HJ Wijma, RJ Floor, S Bjelic, SJ Marrink, D Baker, DB Janssen Angewandte Chemie International Edition 54 (12), 3726-3730, 2015 | 148 | 2015 |
Computational library design for increasing haloalkane dehalogenase stability RJ Floor, HJ Wijma, DI Colpa, A Ramos‐Silva, PA Jekel, W Szymański, ... ChemBioChem 15 (11), 1660-1672, 2014 | 93 | 2014 |
Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks JGE van Leeuwen, HJ Wijma, RJ Floor, JM van der Laan, DB Janssen ChemBioChem 13 (1), 137-148, 2012 | 76 | 2012 |
Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase M Schallmey, RJ Floor, B Hauer, M Breuer, PA Jekel, HJ Wijma, ... ChemBioChem 14 (7), 870-881, 2013 | 63 | 2013 |
A robust cosolvent-compatible halohydrin dehalogenase by computational library design H Arabnejad, M Dal Lago, PA Jekel, RJ Floor, AMWH Thunnissen, ... Protein Engineering, Design and Selection 30 (3), 175-189, 2017 | 61 | 2017 |
X‐ray crystallographic validation of structure predictions used in computational design for protein stabilization RJ Floor, HJ Wijma, PA Jekel, AC Terwisscha van Scheltinga, BW Dijkstra, ... Proteins: Structure, Function, and Bioinformatics 83 (5), 940-951, 2015 | 26 | 2015 |
Hydrolysis and reverse hydrolysis: halohydrin dehalogenases M Schallmey, RJ Floor, W Szymanski, DB Janssen Synthetic Methods VI–Enzymatic and Semi-Enzymatic, 143-155, 2012 | 14 | 2012 |
Characterization of Two VAO-Type Flavoprotein Oxidases from Myceliophthora thermophila AR Ferrari, HJ Rozeboom, ASC Vugts, MJ Koetsier, R Floor, MW Fraaije Molecules 23 (1), 111, 2018 | 9 | 2018 |
Efficient protein engineering by combining computational design and directed evolution R Floor | 1 | 2015 |
Computation-supported enzyme engineering for preparative biocatalysis DB Janssen, R Floor, MM Heberling, S Bartsch, HJ Wijma FEBS JOURNAL 280, 591-592, 2013 | | 2013 |
Enantioselective enzymes by computational design and screening HJ Wijma, RJ Floor, S Bjelic, SJ Marrink, D Baker, DB Janssen | | |
Computational libraries for rapid enzyme stabilization HJ Wijma, RJ Floor, PA Jekel, D Baker, SJ Marrink, DB Janssen | | |