| Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies SM Noh, S Shin, GM Lee Scientific Reports 8 (1), 5361, 2018 | 96 | 2018 |
| Comprehensive analysis of genomic safe harbors as target sites for stable expression of the heterologous gene in HEK293 cells S Shin, SH Kim, SW Shin, LM Grav, LE Pedersen, JS Lee, GM Lee ACS Synthetic Biology 9 (6), 1263-1269, 2020 | 36 | 2020 |
| Improving the secretory capacity of CHO producer cells: the effect of controlled Blimp1 expression, a master transcription factor for plasma cells SH Kim, M Baek, S Park, S Shin, JS Lee, GM Lee Metabolic Engineering 69, 73-86, 2022 | 19 | 2022 |
| Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies F Rocamora, AG Peralta, S Shin, J Sorrentino, MYM Wu, EA Toth, ... Biotechnology advances 67, 108206, 2023 | 17 | 2023 |
| Streamlined human cell-based recombinase-mediated cassette exchange platform enables multigene expression for the production of therapeutic proteins S Shin, SH Kim, JS Lee, GM Lee ACS Synthetic Biology 10 (7), 1715-1727, 2021 | 15 | 2021 |
| Cell line development for therapeutic protein production SM Noh, S Shin, GM Lee Cell culture engineering: Recombinant protein production, 23-47, 2019 | 13 | 2019 |
| Amplification of EBNA-1 through a single-plasmid vector-based gene amplification system in HEK293 cells as an efficient transient gene expression system SH Park, JH Park, JH Lee, HM Lee, YJ Kang, EJ Lee, S Shin, GM Lee, ... Applied Microbiology and Biotechnology 105, 67-76, 2021 | 8 | 2021 |
| Recombinase-mediated cassette exchange-based screening of a CRISPR/Cas9 library for enhanced recombinant protein production in human embryonic kidney cells: Improving … S Shin, SH Kim, JH Park, JS Lee, GM Lee Metabolic Engineering 72, 247-258, 2022 | 5 | 2022 |
| Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP–SETDB1 Complex for Enhancing Difficult-to-Express Protein Production SH Kim, JH Park, S Shin, S Shin, D Chun, YG Kim, J Yoo, WK You, JS Lee, ... ACS Synthetic Biology 13 (2), 634-647, 2024 | 2 | 2024 |
| Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening SH Kim, S Shin, M Baek, K Xiong, KJ la Cour Karottki, H Hefzi, LM Grav, ... Metabolic Engineering 80, 66-77, 2023 | 2 | 2023 |
| Enhancing the production of adeno‐associated virus (AAV) 2 and AAV9 with high full capsid ratio in HEK293 cells through design‐of‐experiment optimization of triple plasmid ratio S Park, S Shin, H Lee, JH Jang, GM Lee Biotechnology Journal 19 (3), 2300667, 2024 | 1 | 2024 |
| Genome-wide CRISPR-Cas9 screen identifies hyperosmotic stress responsive genes in Chinese hamster ovary cells SH Kim, S Shin, M Baek, K Xiong, KJ Cour Karottki, H Hefzi, L Marie Grav, ... | | 2023 |
