Chlamydia infection promotes host DNA damage and proliferation but impairs the DNA damage response C Chumduri, RK Gurumurthy, PK Zadora, Y Mi, TF Meyer Cell host & microbe 13 (6), 746-758, 2013 | 201 | 2013 |
Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia C Chumduri, RK Gurumurthy, H Berger, O Dietrich, N Kumar, S Koster, ... Nature cell biology 23 (2), 184-197, 2021 | 78 | 2021 |
Subversion of host genome integrity by bacterial pathogens C Chumduri, RK Gurumurthy, R Zietlow, TF Meyer Nature reviews Molecular cell biology 17 (10), 659-673, 2016 | 76 | 2016 |
A loss-of-function screen reveals Ras-and Raf-independent MEK-ERK signaling during Chlamydia trachomatis infection RK Gurumurthy, AP Mäurer, N Machuy, S Hess, KP Pleissner, ... Science signaling 3 (113), ra21-ra21, 2010 | 64 | 2010 |
Integrated phosphoproteome and transcriptome analysis reveals chlamydia-induced epithelial-to-mesenchymal transition in host cells PK Zadora, C Chumduri, K Imami, H Berger, Y Mi, M Selbach, TF Meyer, ... Cell Reports 26 (5), 1286-1302. e8, 2019 | 52 | 2019 |
Reduced display of tumor necrosis factor receptor I at the host cell surface supports infection with Chlamydia trachomatis N Paland, L Bohme, RK Gurumurthy, A Mäurer, AJ Szczepek, T Rudel Journal of Biological Chemistry 283 (10), 6438-6448, 2008 | 48 | 2008 |
Combined human genome-wide RNAi and metabolite analyses identify IMPDH as a host-directed target against Chlamydia infection M Rother, E Gonzalez, ART da Costa, L Wask, I Gravenstein, M Pardo, ... Cell host & microbe 23 (5), 661-671. e8, 2018 | 42 | 2018 |
Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming S Koster, RK Gurumurthy, N Kumar, PG Prakash, J Dhanraj, S Bayer, ... Nature communications 13 (1), 1030, 2022 | 39 | 2022 |
Chlamydia trachomatis Inhibits Homologous Recombination Repair of DNA Breaks by Interfering with PP2A Signaling Y Mi, RK Gurumurthy, PK Zadora, TF Meyer, C Chumduri MBio 9 (6), 10.1128/mbio. 01465-18, 2018 | 23 | 2018 |
Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells LP Sepe, K Hartl, A Iftekhar, H Berger, N Kumar, C Goosmann, S Chopra, ... MBio 11 (5), 10.1128/mbio. 01911-20, 2020 | 21 | 2020 |
Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection RK Gurumurthy, S Koster, N Kumar, TF Meyer, C Chumduri Nature Protocols 17 (7), 1658-1690, 2022 | 20 | 2022 |
Dynamin‐mediated lipid acquisition is essential for Chlamydia trachomatis development RK Gurumurthy, C Chumduri, A Karlas, S Kimmig, E Gonzalez, N Machuy, ... Molecular Microbiology 94 (1), 186-201, 2014 | 17 | 2014 |
Transition of Wnt signaling microenvironment delineates the squamo-columnar junction and emergence of squamous metaplasia of the cervix C Chumduri, RK Gurumurthy, H Berger, S Koster, V Brinkmann, U Klemm, ... BioRxiv, 443770, 2018 | 13 | 2018 |
Genotoxic effect of LP Sepe, K Hartl, A Iftekhar, H Berger, N Kumar, C Goosmann, S Chopra, ... Salmonella paratyphi, 2020 | 8 | 2020 |
Spatial organisation and homeostasis of epithelial lineages at the gastroesophageal junction is regulated by the divergent Wnt mucosal microenvironment N Kumar, RK Gurumurthy, PG Prakash, SM Kurian, C Wentland, ... bioRxiv, 2021.08. 05.455222, 2021 | 3 | 2021 |
Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids S Koster, RK Gurumurthy, H Berger, M Drabkina, HJ Mollenkopf, ... bioRxiv, 2021.04. 15.439996, 2021 | 2 | 2021 |
Global assessment of host cell functions involved in the intracellular survival and replication of Chlamydia using RNA interference in human cells RK Gurumurthy Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2010 | 2 | 2010 |
γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids J Dong, D Holthaus, C Peters, S Koster, M Ehsani, A Quevedo-Olmos, ... Frontiers in Immunology 14, 1281646, 2023 | 1 | 2023 |
Spatial analysis of organ-wide RNA, protein expression, and lineage tracing in the female mouse reproductive tract RK Gurumurthy, N Kumar, C Chumduri STAR protocols 2 (4), 100969, 2021 | 1 | 2021 |
Pharmaceutical composition for the treatment of chlamydial infection RK Gurumurthy, AP MÄURER, TF Meyer, M Rother, N Machuy, ... | 1 | 2011 |