The Dfm1 Derlin is required for ERAD retrotranslocation of integral membrane proteins S Neal, PA Jaeger, SH Duttke, C Benner, CK Glass, T Ideker, ... Molecular cell 69 (2), 306-320. e4, 2018 | 112 | 2018 |
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins HL Tienson, DV Dabir, SE Neal, R Loo, SA Hasson, P Boontheung, ... Molecular Biology of the Cell 20 (15), 3481-3490, 2009 | 73 | 2009 |
Direct and essential function for Hrd3 in ER-associated degradation N Vashistha, SE Neal, A Singh, SM Carroll, RY Hampton Proceedings of the National Academy of Sciences 113 (21), 5934-5939, 2016 | 62 | 2016 |
A Cdc48 “retrochaperone” function is required for the solubility of retrotranslocated, integral membrane endoplasmic reticulum-associated degradation (ERAD-M) substrates S Neal, R Mak, EJ Bennett, R Hampton Journal of Biological Chemistry 292 (8), 3112-3128, 2017 | 40 | 2017 |
Osm1 facilitates the transfer of electrons from Erv1 to fumarate in the redox-regulated import pathway in the mitochondrial intermembrane space SE Neal, DV Dabir, J Wijaya, C Boon, CM Koehler Molecular Biology of the Cell 28 (21), 2773-2785, 2017 | 32 | 2017 |
Derlin rhomboid pseudoproteases employ substrate engagement and lipid distortion to enable the retrotranslocation of ERAD membrane substrates A Nejatfard, N Wauer, S Bhaduri, A Conn, S Gourkanti, N Singh, T Kuo, ... Cell reports 37 (3), 2021 | 29 | 2021 |
Juneteenth in STEMM and the barriers to equitable science A Mays, A Byars-Winston, A Hinton, AG Marshall, A Kirabo, A August, ... Cell 186 (12), 2510-2517, 2023 | 22 | 2023 |
HRD complex self-remodeling enables a novel route of membrane protein retrotranslocation S Neal, D Syau, A Nejatfard, S Nadeau, RY Hampton Iscience 23 (9), 2020 | 21 | 2020 |
The role of rhomboid superfamily members in protein homeostasis: Mechanistic insight and physiological implications RR Kandel, SE Neal Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (10), 118793, 2020 | 19 | 2020 |
Mia40 protein serves as an electron sink in the Mia40-Erv1 import pathway SE Neal, DV Dabir, HL Tienson, DM Horn, K Glaeser, RRO Loo, ... Journal of Biological Chemistry 290 (34), 20804-20814, 2015 | 17 | 2015 |
Impaired phosphatidylethanolamine metabolism activates a reversible stress response that detects and resolves mutant mitochondrial precursors PN Sam, E Calzada, MG Acoba, T Zhao, Y Watanabe, A Nejatfard, ... IScience 24 (3), 2021 | 14 | 2021 |
Proteotoxic stress and the ubiquitin proteasome system R Kandel, J Jung, S Neal Seminars in cell & developmental biology, 2023 | 12 | 2023 |
Decoding Transcription Regulatory Mechanisms Associated with Coccidioides immitis Phase Transition Using Total RNA SH Duttke, S Beyhan, R Singh, S Neal, S Viriyakosol, J Fierer, ... Msystems 7 (1), e01404-21, 2022 | 10 | 2022 |
Assays for protein retrotranslocation in ERAD S Neal, SH Duttke, RY Hampton Methods in enzymology 619, 1-26, 2019 | 9 | 2019 |
Quality Control: Maintaining molecular order and preventing cellular chaos S Neal, F Ohtake, AM Cuervo, RS Hegde, U Jakob, M Lazarou, ... Molecular cell 82 (8), 1390-1397, 2022 | 7 | 2022 |
Inner-nuclear-membrane–associated degradation employs Dfm1-independent retrotranslocation and alleviates misfolded transmembrane-protein toxicity MP Flagg, MA Wangeline, SR Holland, SH Duttke, C Benner, S Neal, ... Molecular biology of the cell 32 (7), 521-537, 2021 | 7 | 2021 |
A “retrochaperone” function for Cdc48: the Cdc48 complex is required for retrotranslocated ERAD-M substrate solubility SE Neal, R Mak, EJ Bennett, R Hampton J Biol Chem 292, 3112-3128, 2017 | 7 | 2017 |
An ERAD‐independent role for rhomboid pseudoprotease Dfm1 in mediating sphingolipid homeostasis S Bhaduri, A Aguayo, Y Ohno, M Proietto, J Jung, I Wang, R Kandel, ... The EMBO Journal 42 (4), e112275, 2023 | 4 | 2023 |
Yeast derlin Dfm1 employs a chaperone-like function to resolve misfolded membrane protein stress R Kandel, J Jung, D Syau, T Kuo, L Songster, C Horn, C Chapman, ... PLoS biology 21 (1), e3001950, 2023 | 4 | 2023 |
Assays for studying normal versus suppressive ERAD-associated retrotranslocation pathways in yeast S Bhaduri, SE Neal STAR protocols 2 (3), 100640, 2021 | 4 | 2021 |