Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies A Lorz, T Lorenzi, ME Hochberg, J Clairambault, B Perthame ESAIM: Mathematical Modelling and Numerical Analysis-Modélisation …, 2013 | 156 | 2013 |
Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation RH Chisholm, T Lorenzi, A Lorz, AK Larsen, LN Almeida, A Escargueil, ... Cancer research 75 (6), 930-939, 2015 | 138 | 2015 |
Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors A Lorz, T Lorenzi, J Clairambault, A Escargueil, B Perthame Bulletin of mathematical biology 77, 1-22, 2015 | 137 | 2015 |
Cell population heterogeneity and evolution towards drug resistance in cancer: biological and mathematical assessment, theoretical treatment optimisation RH Chisholm, T Lorenzi, J Clairambault Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (11), 2627-2645, 2016 | 104 | 2016 |
A mathematical framework for modelling the metastatic spread of cancer LC Franssen, T Lorenzi, AEF Burgess, MAJ Chaplain Bulletin of mathematical biology 81, 1965-2010, 2019 | 93 | 2019 |
Tracking the evolution of cancer cell populations through the mathematical lens of phenotype-structured equations T Lorenzi, RH Chisholm, J Clairambault Biology direct 11, 1-17, 2016 | 75 | 2016 |
Dissecting the dynamics of epigenetic changes in phenotype-structured populations exposed to fluctuating environments T Lorenzi, RH Chisholm, L Desvillettes, BD Hughes Journal of theoretical biology 386, 166-176, 2015 | 55 | 2015 |
Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model L Almeida, P Bagnerini, G Fabrini, BD Hughes, T Lorenzi ESAIM: Mathematical Modelling and Numerical Analysis 53 (4), 1157-1190, 2019 | 47 | 2019 |
Evolutionary dynamics of phenotype-structured populations: from individual-level mechanisms to population-level consequences RH Chisholm, T Lorenzi, L Desvillettes, BD Hughes Zeitschrift für angewandte Mathematik und Physik 67, 1-34, 2016 | 47 | 2016 |
Social information use and the evolution of unresponsiveness in collective systems CJ Torney, T Lorenzi, ID Couzin, SA Levin Journal of the Royal Society Interface 12 (103), 20140893, 2015 | 45 | 2015 |
On interfaces between cell populations with different mobilities T Lorenzi, A Lorz, B Perthame American Institute of Mathematical Sciences (AIMS), 2016 | 39 | 2016 |
The role of spatial variations of abiotic factors in mediating intratumour phenotypic heterogeneity T Lorenzi, C Venkataraman, A Lorz, MAJ Chaplain Journal of theoretical biology 451, 101-110, 2018 | 35 | 2018 |
A mathematical model for immune and autoimmune response mediated by T-cells M Delitala, U Dianzani, T Lorenzi, M Melensi Computers & Mathematics with Applications 66 (6), 1010-1023, 2013 | 34 | 2013 |
A mathematical dissection of the adaptation of cell populations to fluctuating oxygen levels A Ardaševa, RA Gatenby, ARA Anderson, HM Byrne, PK Maini, T Lorenzi Bulletin of mathematical biology 82, 1-24, 2020 | 31 | 2020 |
Modelling the immune response to cancer: an individual-based approach accounting for the difference in movement between inactive and activated T cells FR Macfarlane, T Lorenzi, MAJ Chaplain Bulletin of mathematical biology 80, 1539-1562, 2018 | 31 | 2018 |
Bridging the gap between individual-based and continuum models of growing cell populations MAJ Chaplain, T Lorenzi, FR Macfarlane Journal of Mathematical Biology 80 (1), 343-371, 2020 | 30 | 2020 |
Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments A Ardaševa, RA Gatenby, ARA Anderson, HM Byrne, PK Maini, T Lorenzi Journal of mathematical biology 80, 775-807, 2020 | 29 | 2020 |
From a discrete model of chemotaxis with volume-filling to a generalized Patlak–Keller–Segel model F Bubba, T Lorenzi, FR Macfarlane Proceedings of the Royal Society A 476 (2237), 20190871, 2020 | 26 | 2020 |
Effects of an advection term in nonlocal lotka–volterra equations RH Chisholm, T Lorenzi, A Lorz Communications in mathematical sciences 14 (4), 1181-1188, 2016 | 26 | 2016 |
Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy REA Stace, T Stiehl, MAJ Chaplain, A Marciniak-Czochra, T Lorenzi Mathematical Modelling of Natural Phenomena 15, 14, 2020 | 25 | 2020 |