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Nemil N Bhatt
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Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons
Z Ruan, D Pathak, S Venkatesan Kalavai, A Yoshii-Kitahara, S Muraoka, ...
Brain 144 (1), 288-309, 2021
1672021
Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross‐seeding behavior
G Ghag, N Bhatt, DV Cantu, MJ Guerrero‐Munoz, A Ellsworth, ...
Protein Science 27 (11), 1901-1909, 2018
1122018
Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia
S Gaikwad, N Puangmalai, A Bittar, M Montalbano, S Garcia, S McAllen, ...
Cell reports 36 (3), 2021
1092021
P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
KM Farmer, G Ghag, N Puangmalai, M Montalbano, N Bhatt, R Kayed
Acta neuropathologica communications 8, 1-21, 2020
962020
Advances and considerations in AD tau-targeted immunotherapy
A Bittar, N Bhatt, R Kayed
Neurobiology of disease 134, 104707, 2020
912020
Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer’s disease, progressive supranuclear palsy and dementia with Lewy bodies
N Puangmalai, N Bhatt, M Montalbano, U Sengupta, S Gaikwad, ...
Cell death & disease 11 (5), 314, 2020
762020
RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
M Montalbano, S McAllen, N Puangmalai, U Sengupta, N Bhatt, ...
Nature Communications 11 (1), 4305, 2020
662020
TDP-43 and tau oligomers in Alzheimer's disease, amyotrophic lateral sclerosis, and frontotemporal dementia
M Montalbano, S McAllen, FL Cascio, U Sengupta, S Garcia, N Bhatt, ...
Neurobiology of disease 146, 105130, 2020
592020
Neurotoxic tau oligomers after single versus repetitive mild traumatic brain injury
A Bittar, N Bhatt, TF Hasan, M Montalbano, N Puangmalai, S McAllen, ...
Brain communications 1 (1), fcz004, 2019
372019
Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration
M Montalbano, S McAllen, U Sengupta, N Puangmalai, N Bhatt, ...
Aging Cell 18 (6), e13035, 2019
342019
Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer’s disease
N Puangmalai, U Sengupta, N Bhatt, S Gaikwad, M Montalbano, ...
Journal of Biological Chemistry 298 (4), 2022
282022
Polymorphic α-synuclein strains modified by dopamine and docosahexaenoic acid interact differentially with tau protein
U Sengupta, N Puangmalai, N Bhatt, S Garcia, Y Zhao, R Kayed
Molecular Neurobiology 57, 2741-2765, 2020
262020
Passive immunotherapy targeting tau oligomeric strains reverses tauopathy phenotypes in aged human-tau mice in a mouse model-specific manner
A Bittar, R Al-Lahham, N Bhatt, K Moore, M Montalbano, C Jerez, L Fung, ...
Journal of Alzheimer's Disease 90 (3), 1103-1122, 2022
142022
Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein
S Dhakal, AS Robang, N Bhatt, N Puangmalai, L Fung, R Kayed, ...
Journal of Biological Chemistry 298 (11), 2022
92022
Polymorphic alpha-synuclein oligomers: characterization and differential detection with novel corresponding antibodies
K Moore, U Sengupta, N Puangmalai, N Bhatt, R Kayed
Molecular neurobiology 60 (5), 2691-2705, 2023
22023
Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils
AA Desai, JM Zupancic, H Trzeciakiewicz, JE Gerson, KN DuBois, ...
bioRxiv, 2023.07. 04.547698, 2023
22023
In pursuit of degenerative brain disease diagnosis: Dementia biomarkers detected by DNA aptamer-attached portable graphene biosensor
TA Bodily, A Ramanathan, S Wei, A Karkisaval, N Bhatt, C Jerez, ...
Proceedings of the National Academy of Sciences 120 (47), e2311565120, 2023
12023
Quantification and targeting of elusive neurotoxic amyloid oligomers
N Bhatt, R Kayed
Cell Reports Medicine 3 (5), 2022
12022
Development of a pan‐tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates
N McArthur, B Kang, FG Rivera Moctezuma, AT Shaikh, K Loeffler, ...
Biotechnology Progress, e3463, 2024
2024
Effect of Natural Osmolytes on Recombinant Tau Monomer: Propensity of Oligomerization and Aggregation
S Arar, MA Haque, N Bhatt, Y Zhao, R Kayed
ACS chemical neuroscience 15 (7), 1366-1377, 2024
2024
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