Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons Z Ruan, D Pathak, S Venkatesan Kalavai, A Yoshii-Kitahara, S Muraoka, ... Brain 144 (1), 288-309, 2021 | 167 | 2021 |
Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross‐seeding behavior G Ghag, N Bhatt, DV Cantu, MJ Guerrero‐Munoz, A Ellsworth, ... Protein Science 27 (11), 1901-1909, 2018 | 112 | 2018 |
Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia S Gaikwad, N Puangmalai, A Bittar, M Montalbano, S Garcia, S McAllen, ... Cell reports 36 (3), 2021 | 109 | 2021 |
P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease KM Farmer, G Ghag, N Puangmalai, M Montalbano, N Bhatt, R Kayed Acta neuropathologica communications 8, 1-21, 2020 | 96 | 2020 |
Advances and considerations in AD tau-targeted immunotherapy A Bittar, N Bhatt, R Kayed Neurobiology of disease 134, 104707, 2020 | 91 | 2020 |
Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer’s disease, progressive supranuclear palsy and dementia with Lewy bodies N Puangmalai, N Bhatt, M Montalbano, U Sengupta, S Gaikwad, ... Cell death & disease 11 (5), 314, 2020 | 76 | 2020 |
RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction M Montalbano, S McAllen, N Puangmalai, U Sengupta, N Bhatt, ... Nature Communications 11 (1), 4305, 2020 | 66 | 2020 |
TDP-43 and tau oligomers in Alzheimer's disease, amyotrophic lateral sclerosis, and frontotemporal dementia M Montalbano, S McAllen, FL Cascio, U Sengupta, S Garcia, N Bhatt, ... Neurobiology of disease 146, 105130, 2020 | 59 | 2020 |
Neurotoxic tau oligomers after single versus repetitive mild traumatic brain injury A Bittar, N Bhatt, TF Hasan, M Montalbano, N Puangmalai, S McAllen, ... Brain communications 1 (1), fcz004, 2019 | 37 | 2019 |
Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration M Montalbano, S McAllen, U Sengupta, N Puangmalai, N Bhatt, ... Aging Cell 18 (6), e13035, 2019 | 34 | 2019 |
Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer’s disease N Puangmalai, U Sengupta, N Bhatt, S Gaikwad, M Montalbano, ... Journal of Biological Chemistry 298 (4), 2022 | 28 | 2022 |
Polymorphic α-synuclein strains modified by dopamine and docosahexaenoic acid interact differentially with tau protein U Sengupta, N Puangmalai, N Bhatt, S Garcia, Y Zhao, R Kayed Molecular Neurobiology 57, 2741-2765, 2020 | 26 | 2020 |
Passive immunotherapy targeting tau oligomeric strains reverses tauopathy phenotypes in aged human-tau mice in a mouse model-specific manner A Bittar, R Al-Lahham, N Bhatt, K Moore, M Montalbano, C Jerez, L Fung, ... Journal of Alzheimer's Disease 90 (3), 1103-1122, 2022 | 14 | 2022 |
Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein S Dhakal, AS Robang, N Bhatt, N Puangmalai, L Fung, R Kayed, ... Journal of Biological Chemistry 298 (11), 2022 | 9 | 2022 |
Polymorphic alpha-synuclein oligomers: characterization and differential detection with novel corresponding antibodies K Moore, U Sengupta, N Puangmalai, N Bhatt, R Kayed Molecular neurobiology 60 (5), 2691-2705, 2023 | 2 | 2023 |
Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils AA Desai, JM Zupancic, H Trzeciakiewicz, JE Gerson, KN DuBois, ... bioRxiv, 2023.07. 04.547698, 2023 | 2 | 2023 |
In pursuit of degenerative brain disease diagnosis: Dementia biomarkers detected by DNA aptamer-attached portable graphene biosensor TA Bodily, A Ramanathan, S Wei, A Karkisaval, N Bhatt, C Jerez, ... Proceedings of the National Academy of Sciences 120 (47), e2311565120, 2023 | 1 | 2023 |
Quantification and targeting of elusive neurotoxic amyloid oligomers N Bhatt, R Kayed Cell Reports Medicine 3 (5), 2022 | 1 | 2022 |
Development of a pan‐tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates N McArthur, B Kang, FG Rivera Moctezuma, AT Shaikh, K Loeffler, ... Biotechnology Progress, e3463, 2024 | | 2024 |
Effect of Natural Osmolytes on Recombinant Tau Monomer: Propensity of Oligomerization and Aggregation S Arar, MA Haque, N Bhatt, Y Zhao, R Kayed ACS chemical neuroscience 15 (7), 1366-1377, 2024 | | 2024 |