DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45 K Rai, IJ Huggins, SR James, AR Karpf, DA Jones, BR Cairns Cell 135 (7), 1201-1212, 2008 | 818 | 2008 |
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication PO Estève, HG Chin, A Smallwood, GR Feehery, O Gangisetty, AR Karpf, ... Genes & development 20 (22), 3089-3103, 2006 | 615 | 2006 |
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss CJ Klein, MV Botuyan, Y Wu, CJ Ward, GA Nicholson, S Hammans, ... Nature genetics 43 (6), 595-600, 2011 | 435 | 2011 |
Reactivating the expression of methylation silenced genes in human cancer AR Karpf, DA Jones Oncogene 21 (35), 5496-5503, 2002 | 334 | 2002 |
Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells AR Karpf, S Matsui Cancer research 65 (19), 8635-8639, 2005 | 324 | 2005 |
Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry L Song, SR James, L Kazim, AR Karpf Analytical chemistry 77 (2), 504-510, 2005 | 267 | 2005 |
Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells AR Karpf, PW Peterson, JT Rawlins, BK Dalley, Q Yang, H Albertsen, ... Proceedings of the National Academy of Sciences 96 (24), 14007-14012, 1999 | 233 | 1999 |
Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish K Rai, S Chidester, CV Zavala, EJ Manos, SR James, AR Karpf, DA Jones, ... Genes & development 21 (3), 261-266, 2007 | 231 | 2007 |
Association between global DNA hypomethylation in leukocytes and risk of breast cancer JY Choi, SR James, PA Link, SE McCann, CC Hong, W Davis, ... Carcinogenesis 30 (11), 1889-1897, 2009 | 228 | 2009 |
Superinfection exclusion of alphaviruses in three mosquito cell lines persistently infected with Sindbis virus AR Karpf, E Lenches, EG Strauss, JH Strauss, DT Brown Journal of virology 71 (9), 7119-7123, 1997 | 201 | 1997 |
Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2′-deoxycytidine AR Karpf, BC Moore, TO Ririe, DA Jones Molecular pharmacology 59 (4), 751-757, 2001 | 200 | 2001 |
Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer K Odunsi, J Matsuzaki, SR James, P Mhawech-Fauceglia, T Tsuji, A Miller, ... Cancer immunology research 2 (1), 37-49, 2014 | 193 | 2014 |
Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine AR Karpf, AW Lasek, TO Ririe, AN Hanks, D Grossman, DA Jones Molecular pharmacology 65 (1), 18-27, 2004 | 186 | 2004 |
Pan-cancer analyses reveal genomic features of FOXM1 overexpression in cancer CJ Barger, C Branick, L Chee, AR Karpf Cancers 11 (2), 251, 2019 | 182 | 2019 |
Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development K Rai, LD Nadauld, S Chidester, EJ Manos, SR James, AR Karpf, ... Molecular and cellular biology, 2006 | 181 | 2006 |
Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation WE Samlowski, SA Leachman, M Wade, P Cassidy, P Porter-Gill, L Busby, ... Journal of Clinical Oncology 23 (17), 3897-3905, 2005 | 170 | 2005 |
Increased expression of androgen receptor coregulator MAGE-11 in prostate cancer by DNA hypomethylation and cyclic AMP AR Karpf, S Bai, SR James, JL Mohler, EM Wilson Molecular Cancer Research 7 (4), 523-535, 2009 | 155 | 2009 |
Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish 2 K Rai, IF Jafri, S Chidester, SR James, AR Karpf, BR Cairns, DA Jones Journal of Biological Chemistry 285 (6), 4110-4121, 2010 | 147 | 2010 |
Regulation of cancer germline antigen gene expression: implications for cancer immunotherapy SN Akers, K Odunsi, AR Karpf Future oncology 6 (5), 717-732, 2010 | 141 | 2010 |
Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b SR James, PA Link, AR Karpf Oncogene 25 (52), 6975-6985, 2006 | 137 | 2006 |