Nanoparticle‐conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses L Nuhn, S De Koker, S Van Lint, Z Zhong, JP Catani, F Combes, ... Advanced Materials 30 (45), 1803397, 2018 | 147 | 2018 |
mRNA therapeutics deliver a hopeful message Z Zhong, S Mc Cafferty, F Combes, H Huysmans, J De Temmerman, ... Nano today 23, 16-39, 2018 | 125 | 2018 |
Heat-Stable Enterotoxins of Enterotoxigenic Escherichia coli and Their Impact on Host Immunity H Wang, Z Zhong, Y Luo, E Cox, B Devriendt Toxins 11 (1), 24, 2019 | 103 | 2019 |
Current status of COVID‐19 (pre) clinical vaccine development T Ye, Z Zhong, A García‐Sastre, M Schotsaert, BG De Geest Angewandte Chemie International Edition 59 (43), 18885-18897, 2020 | 80 | 2020 |
Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles B Wang, S Van Herck, Y Chen, X Bai, Z Zhong, K Deswarte, ... Journal of the American Chemical Society 142 (28), 12133-12139, 2020 | 80 | 2020 |
Expression kinetics and innate immune response after electroporation and LNP-mediated delivery of a self-amplifying mRNA in the skin H Huysmans, Z Zhong, J De Temmerman, BL Mui, YK Tam, S Mc Cafferty, ... Molecular Therapy-Nucleic Acids 17, 867-878, 2019 | 71 | 2019 |
Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine S Jangra, J De Vrieze, A Choi, R Rathnasinghe, G Laghlali, A Uvyn, ... Angewandte Chemie International Edition 60 (17), 9467-9473, 2021 | 63 | 2021 |
Lymph-node-targeted immune activation by engineered block copolymer amphiphiles–TLR7/8 agonist conjugates S Van Herck, K Deswarte, L Nuhn, Z Zhong, JP Portela Catani, Y Li, ... Journal of the American Chemical Society 140 (43), 14300-14307, 2018 | 59 | 2018 |
Potent lymphatic translocation and spatial control over innate immune activation by polymer–lipid amphiphile conjugates of small‐molecule TLR7/8 agonists J De Vrieze, B Louage, K Deswarte, Z Zhong, R De Coen, S Van Herck, ... Angewandte Chemie International Edition 58 (43), 15390-15395, 2019 | 56 | 2019 |
Immunogenicity and protection efficacy of a naked self-replicating mRNA-based Zika virus vaccine Z Zhong, JP Portela Catani, S Mc Cafferty, L Couck, W Van Den Broeck, ... Vaccines 7 (3), 96, 2019 | 53 | 2019 |
Squaric ester-based, pH-degradable nanogels: modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators A Huppertsberg, L Kaps, Z Zhong, S Schmitt, J Stickdorn, K Deswarte, ... Journal of the American Chemical Society 143 (26), 9872-9883, 2021 | 52 | 2021 |
The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines is determined by the route of administration L Van Hoecke, K Roose, M Ballegeer, Z Zhong, NN Sanders, S De Koker, ... Molecular Therapy-Nucleic Acids 22, 373-381, 2020 | 45 | 2020 |
Lipid-polyglutamate nanoparticle vaccine platform D Van Lysebetten, A Malfanti, K Deswarte, K Koynov, B Golba, T Ye, ... ACS applied materials & interfaces 13 (5), 6011-6022, 2021 | 30 | 2021 |
Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs Z Zhong, S McCafferty, L Opsomer, H Wang, H Huysmans, ... Molecular Therapy 29 (4), 1370-1381, 2021 | 29 | 2021 |
Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids A Lamoot, J Lammens, E De Lombaerde, Z Zhong, M Gontsarik, Y Chen, ... Biomaterials Science 11 (12), 4327-4334, 2023 | 28 | 2023 |
Molecular characterization and expression analysis of the duck viperin gene Z Zhong, Y Ji, Y Fu, B Liu, Q Zhu Gene 570 (1), 100-107, 2015 | 25 | 2015 |
Transient lymph node immune activation by hydrolysable polycarbonate Nanogels C Czysch, C Medina‐Montano, Z Zhong, A Fuchs, J Stickdorn, ... Advanced Functional Materials 32 (35), 2203490, 2022 | 22 | 2022 |
Visible Light Conjugation with Triazolinediones as a Route to Degradable Poly (ethylene glycol)–Lipids for mRNA Lipid Nanoparticle Formulation B Golba, M Soete, Z Zhong, N Sanders, FE Du Prez, HA Houck, ... Angewandte Chemie 135 (23), e202301102, 2023 | 15 | 2023 |
Imidazoquinoline-conjugated degradable Coacervate conjugate for local Cancer immunotherapy H Li, S Van Herck, Y Liu, Y Hao, X Ding, L Nuhn, Z Zhong, F Combes, ... ACS biomaterials science & engineering 6 (9), 4993-5000, 2020 | 15 | 2020 |
Improving the repeatability and efficacy of intradermal electroporated self-replicating mRNA H Huysmans, J De Temmerman, Z Zhong, S Mc Cafferty, F Combes, ... Molecular Therapy-Nucleic Acids 17, 388-395, 2019 | 15 | 2019 |