Putting chirality to work: the strategy of chiral switches I Agranat, H Caner, J Caldwell Nature Reviews Drug Discovery 1 (10), 753-768, 2002 | 753 | 2002 |
The metabolic chiral inversion of 2-arylpropionic acids—a novel route with pharmacological consequences AJ Hutt, J Caldwell Journal of Pharmacy and Pharmacology 35 (11), 693-704, 1983 | 521 | 1983 |
The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences J Caldwell, AJ Hutt, S Fournel-Gigleux Biochemical pharmacology 37 (1), 105-114, 1988 | 463 | 1988 |
Metabolism of [14C]methamphetamine in man, the guinea pig and the rat J Caldwell, LG Dring, RT Williams Biochemical Journal 129 (1), 11-22, 1972 | 347 | 1972 |
Safety assessment of allylalkoxybenzene derivatives used as flavouring substances—methyl eugenol and estragole RL Smith, TB Adams, J Doull, VJ Feron, JI Goodman, LJ Marnett, ... Food and chemical Toxicology 40 (7), 851-870, 2002 | 275 | 2002 |
The importance of stereochemistry in the clinical pharmacokinetics of the 2-arylpropionic acid non-steroidal anti-inflammatory drugs AJ Hutt, J Caldwell Clinical Pharmacokinetics 9 (4), 371-373, 1984 | 260 | 1984 |
Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity GP Aithal, L Ramsay, AK Daly, N Sonchit, JBS Leathart, G Alexander, ... Hepatology 39 (5), 1430-1440, 2004 | 256 | 2004 |
An introduction to drug disposition: the basic principles of absorption, distribution, metabolism, and excretion J Caldwell, I Gardner, N Swales Toxicologic pathology 23 (2), 102-114, 1995 | 195 | 1995 |
Importance of stereospecific bionalytical monitoring in drug development J Caldwell Journal of chromatography A 719 (1), 3-13, 1996 | 167 | 1996 |
Genotoxicity of the alkenylbenzenes α− and β-asarone, myristicin and elemicin as determined by the UDS assay in cultured rat hepatocytes G Hasheminejad, J Caldwell Food and Chemical Toxicology 32 (3), 223-231, 1994 | 163 | 1994 |
The metabolism of amphetamines in mammals J Caldwell Drug metabolism reviews 5 (2), 219-280, 1976 | 158 | 1976 |
Stereochemical determinants of the nature and consequences of drug metabolism J Caldwell Journal of Chromatography A 694 (1), 39-48, 1995 | 152 | 1995 |
The metabolism of aspirin in man: a population study AJ Hutt, J Caldwell, RL Smith Xenobiotica 16 (3), 239-249, 1986 | 131 | 1986 |
Conjugation reactions in foreign-compound metabolism: definition, consequences, and species variations J Caldwell Drug metabolism reviews 13 (5), 745-777, 1982 | 128 | 1982 |
Metabolism of estragole in rat and mouse and influence of dose size on excretion of the proximate carcinogen 1′-hydroxyestragole A Anthony, J Caldwell, AJ Hutt, RL Smith Food and Chemical Toxicology 25 (11), 799-806, 1987 | 123 | 1987 |
The metabolic disposition of [methoxy-14C]-labelled trans-anethole, estragole and p-propylanisole in human volunteers SA Sangster, J Caldwell, AJ Hutt, A Anthony, RL Smith Xenobiotica 17 (10), 1223-1232, 1987 | 123 | 1987 |
Influence of methylxanthine‐containing foods on theophylline metabolism and kinetics TJ Monks, J Caldwell, RL Smith Clinical Pharmacology & Therapeutics 26 (4), 513-524, 1979 | 123 | 1979 |
Structure-specificity of the genotoxicity of some naturally occurring alkenylbenzenes determined by the unscheduled DNA synthesis assay in rat hepatocytes AJ Howes, VSW Chan, J Caldwell Food and Chemical Toxicology 28 (8), 537-542, 1990 | 117 | 1990 |
The current status of attempts to predict species differences in drug metabolism J Caldwell Drug Metabolism Reviews 12 (2), 221-237, 1981 | 111 | 1981 |
Amino acid conjugation AJ Hutt, J Caldwell Conjugation reactions in drug metabolism: An integrated approach, 273-305, 1990 | 108 | 1990 |