CD137 agonist therapy can reprogram regulatory T cells into cytotoxic CD4+ T cells with antitumor activity I Akhmetzyanova, G Zelinskyy, E Littwitz-Salomon, A Malyshkina, ... The Journal of Immunology 196 (1), 484-492, 2016 | 91 | 2016 |
IL-10–producing Tfh cells accumulate with age and link inflammation with age-related immune suppression M Almanan, J Raynor, I Ogunsulire, A Malyshkina, S Mukherjee, ... Science advances 6 (31), eabb0806, 2020 | 88 | 2020 |
The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10+ Regulatory T Cells During Acute Retroviral Infection E Littwitz-Salomon, A Malyshkina, S Schimmer, U Dittmer Frontiers in immunology 9, 1947, 2018 | 37 | 2018 |
Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection A Malyshkina, E Littwitz-Salomon, K Sutter, G Zelinskyy, S Windmann, ... Scientific reports 7 (1), 7785, 2017 | 33 | 2017 |
Diverse Immunomodulatory Effects of Individual IFNα Subtypes on Virus-Specific CD8+ T Cell Responses J Dickow, S Francois, RL Kaiserling, A Malyshkina, I Drexler, ... Frontiers in Immunology 10, 2255, 2019 | 29 | 2019 |
Infection of B cell follicle-resident cells by Friend retrovirus occurs during acute infection and is maintained during viral persistence S Windmann, L Otto, CP Hrycak, A Malyshkina, N Bongard, P David, ... MBio 10 (1), 10.1128/mbio. 00004-19, 2019 | 15 | 2019 |
Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection N Bongard, VTK Le-Trilling, A Malyshkina, M Rückborn, K Wohlgemuth, ... PLoS pathogens 15 (9), e1008043, 2019 | 8 | 2019 |
Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor VTK Le‐Trilling, S Banchenko, D Paydar, PM Leipe, L Binting, S Lauer, ... The EMBO Journal 42 (5), e112351, 2023 | 6 | 2023 |
Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillance A Malyshkina, E Littwitz-Salomon, K Sutter, JA Ross, A Paschen, ... Cancer Immunology, Immunotherapy 68, 479-488, 2019 | 5 | 2019 |
Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral Infection M Schwerdtfeger, J Dickow, Y Schmitz, S Francois, Z Karakoese, ... Frontiers in Immunology 12, 809774, 2022 | 4 | 2022 |
Cytotoxic CD4+ T cells in chronic viral infections and cancer A Malyshkina, A Brüggemann, A Paschen, U Dittmer Frontiers in Immunology 14, 1271236, 2023 | 3 | 2023 |
Immune suppression of vaccine-induced CD8+ T-cell responses by gamma retrovirus envelope is mediated by interleukin-10-producing CD4+ T cells P Podschwadt, A Malyshkina, S Windmann, A Papadamakis, L Kerkmann, ... Frontiers in Immunology 13, 934399, 2022 | 3 | 2022 |
Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell follicles A Malyshkina, W Bayer, P Podschwadt, L Otto, Z Karakoese, K Sutter, ... PLoS Pathogens 19 (10), e1011725, 2023 | 1 | 2023 |
A detailed analysis of F-MuLV-and SFFV-infected cells in Friend virus-infected mice reveals the contribution of both F-MuLV-and SFFV-infected cells to the interleukin-10 host … P Podschwadt, A Malyshkina, S Windmann, T Werner, W Hansen, ... Retrovirology 19 (1), 29, 2022 | 1 | 2022 |
Reduced vacuolar ATPase protects mice from Friend virus infection –an unintended but instructive effect in Hif-2afl mice T Schreiber, N Koll, C Padberg, B delos Reyes, T Quinting, A Malyshkina, ... Journal of Cell Science, jcs. 261893, 2024 | | 2024 |
Rat cytomegalovirus efficiently replicates in dendritic cells and induces changes in their transcriptional profile JC Madela-Mönchinger, SA Wolf, E Wyler, A Bauer, M Mischke, L Möller, ... Frontiers in Immunology 14, 1192057, 2023 | | 2023 |
Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism VT Khanh Le-Trilling, S Banchenko, D Paydar, PM Leipe, L Binting, ... bioRxiv, 2022.05. 05.490734, 2022 | | 2022 |
Inhibition of IL-2 or NF-κB Subunit c-Rel-Dependent Signaling Inhibits Expansion of Regulatory T Cells During Acute Friend Retrovirus Infection JA Ross, A Malyshkina, L Otto, J Liu, U Dittmer Viral Immunology 33 (5), 353-360, 2020 | | 2020 |
Augmentation of Tumor and Virus Specific T Cell Cytotoxicity by Agonistic CD137 Antibody During Chronic Friend Retrovirus Infection A Malyshkina University of Duisburg-Essen, 2019 | | 2019 |