Microglia emerge from erythromyeloid precursors via Pu. 1-and Irf8-dependent pathways K Kierdorf, D Erny, T Goldmann, V Sander, C Schulz, EG Perdiguero, ... Nature neuroscience 16 (3), 273-280, 2013 | 1552 | 2013 |
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology RH De'Broski, C Hölscher, M Mohrs, B Arendse, A Schwegmann, ... Immunity 20 (5), 623-635, 2004 | 888 | 2004 |
LTBI: latent tuberculosis infection or lasting immune responses to M. tuberculosis? A TBNET consensus statement U Mack, GB Migliori, M Sester, HL Rieder, S Ehlers, D Goletti, A Bossink, ... European Respiratory Journal 33 (5), 956-973, 2009 | 835 | 2009 |
Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt+ innate lymphocytes C Vonarbourg, A Mortha, VL Bui, PP Hernandez, EA Kiss, T Hoyler, ... Immunity 33 (5), 736-751, 2010 | 729 | 2010 |
Cutting Edge: Toll-Like Receptor (TLR)2- and TLR4-Mediated Pathogen Recognition in Resistance to Airborne Infection with Mycobacterium tuberculosis N Reiling, C Hölscher, A Fehrenbach, S Kröger, CJ Kirschning, ... The Journal of Immunology 169 (7), 3480-3484, 2002 | 604 | 2002 |
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke M Gelderblom, A Weymar, C Bernreuther, J Velden, P Arunachalam, ... Blood 120 (18), 3793-3802, 2012 | 476 | 2012 |
Common patterns and disease-related signatures in tuberculosis and sarcoidosis J Maertzdorf, J Weiner 3rd, HJ Mollenkopf, T Network, T Bauer, A Prasse, ... Proceedings of the National Academy of Sciences 109 (20), 7853-7858, 2012 | 381 | 2012 |
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRγ–Syk–Card9–dependent innate immune activation K Werninghaus, A Babiak, O Groß, C Hölscher, H Dietrich, EM Agger, ... Journal of Experimental Medicine 206 (1), 89-97, 2009 | 368 | 2009 |
The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis C Hölscher, A Hölscher, D Ruckerl, T Yoshimoto, H Yoshida, T Mak, ... The Journal of Immunology 174 (6), 3534-3544, 2005 | 355 | 2005 |
Interleukin (IL)-23 mediates Toxoplasma gondii–induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17 M Muñoz, MM Heimesaat, K Danker, D Struck, U Lohmann, R Plickert, ... Journal of Experimental Medicine 206 (13), 3047-3059, 2009 | 322 | 2009 |
Defective Nitric Oxide Effector Functions Lead to Extreme Susceptibility of Trypanosoma cruzi-Infected Mice Deficient in Gamma Interferon Receptor or Inducible … C Hölscher, G Köhler, U Müller, H Mossmann, GA Schaub, ... Infection and immunity 66 (3), 1208-1215, 1998 | 310 | 1998 |
A protective and agonistic function of IL-12p40 in mycobacterial infection C Holscher, RA Atkinson, B Arendse, N Brown, E Myburgh, G Alber, ... The Journal of Immunology 167 (12), 6957-6966, 2001 | 309 | 2001 |
Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection PP Hernández, T Mahlakõiv, I Yang, V Schwierzeck, N Nguyen, ... Nature immunology 16 (7), 698-707, 2015 | 307 | 2015 |
The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis HJ Paust, JE Turner, OM Steinmetz, A Peters, F Heymann, C Ho, G Wolf, ... Journal of the American Society of Nephrology 20 (5), 969-979, 2009 | 304 | 2009 |
Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum G Van Zandbergen, A Bollinger, A Wenzel, S Kamhawi, R Voll, M Klinger, ... Proceedings of the National Academy of Sciences 103 (37), 13837-13842, 2006 | 268 | 2006 |
Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, ‐4 and ‐9 C Hölscher, N Reiling, UE Schaible, A Hölscher, C Bathmann, D Korbel, ... European journal of immunology 38 (3), 680-694, 2008 | 225 | 2008 |
Tumor Necrosis Factor Alpha-Mediated Toxic Shock inTrypanosoma cruzi-Infected Interleukin 10-Deficient Mice C Hölscher, M Mohrs, WJ Dai, G Köhler, B Ryffel, GA Schaub, ... Infection and immunity 68 (7), 4075-4083, 2000 | 207 | 2000 |
The power of combinatorial immunology: IL-12 and IL-12-related dimeric cytokines in infectious diseases C Hölscher Medical microbiology and immunology 193, 1-17, 2004 | 201 | 2004 |
IL-17A is produced by Th17, γδ T cells and other CD4− lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial … SM Schulz, G Köhler, C Holscher, Y Iwakura, G Alber International immunology 20 (9), 1129-1138, 2008 | 200 | 2008 |
Autocrine IL-10 induces hallmarks of alternative activation in macrophages and suppresses antituberculosis effector mechanisms without compromising T cell immunity T Schreiber, S Ehlers, L Heitmann, A Rausch, J Mages, PJ Murray, ... The Journal of Immunology 183 (2), 1301-1312, 2009 | 197 | 2009 |