MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data G Finak, A McDavid, M Yajima, J Deng, V Gersuk, AK Shalek, CK Slichter, ... Genome biology 16, 1-13, 2015 | 2427 | 2015 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2276 | 2019 |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2164 | 2011 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 923 | 2017 |
Detectable clonal mosaicism from birth to old age and its relationship to cancer CC Laurie, CA Laurie, K Rice, KF Doheny, LR Zelnick, CP McHugh, ... Nature genetics 44 (6), 642-650, 2012 | 645 | 2012 |
Quality control procedures for genome‐wide association studies S Turner, LL Armstrong, Y Bradford, CS Carlson, DC Crawford, ... Current protocols in human genetics 68 (1), 1.19. 1-1.19. 18, 2011 | 469 | 2011 |
Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments A McDavid, G Finak, PK Chattopadyay, M Dominguez, L Lamoreaux, ... Bioinformatics 29 (4), 461-467, 2013 | 401 | 2013 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 291 | 2016 |
Assessment of the genetic variance of late-onset Alzheimer's disease PG Ridge, KB Hoyt, K Boehme, S Mukherjee, PK Crane, JL Haines, ... Neurobiology of aging 41, 200. e13-200. e20, 2016 | 258 | 2016 |
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study AC Naj, G Jun, C Reitz, BW Kunkle, W Perry, YS Park, GW Beecham, ... JAMA neurology 71 (11), 1394-1404, 2014 | 204 | 2014 |
Transethnic genome‐wide scan identifies novel Alzheimer's disease loci GR Jun, J Chung, J Mez, R Barber, GW Beecham, DA Bennett, ... Alzheimer's & Dementia 13 (7), 727-738, 2017 | 187 | 2017 |
Distinct activation thresholds of human conventional and innate-like memory T cells CK Slichter, A McDavid, HW Miller, G Finak, BJ Seymour, JP McNevin, ... JCI insight 1 (8), 2016 | 140 | 2016 |
Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network DR Crosslin, A McDavid, N Weston, SC Nelson, X Zheng, E Hart, ... Human genetics 131, 639-652, 2012 | 135 | 2012 |
Aged marrow macrophages expand platelet-biased hematopoietic stem cells via interleukin-1B BJ Frisch, CM Hoffman, SE Latchney, MW LaMere, J Myers, J Ashton, ... JCI insight 4 (10), 2019 | 114 | 2019 |
Granzyme K+ CD8 T cells form a core population in inflamed human tissue AH Jonsson, F Zhang, G Dunlap, E Gomez-Rivas, GFM Watts, HJ Faust, ... Science translational medicine 14 (649), eabo0686, 2022 | 104 | 2022 |
Neonatal gut and respiratory microbiota: coordinated development through time and space A Grier, A McDavid, B Wang, X Qiu, J Java, S Bandyopadhyay, H Yang, ... Microbiome 6, 1-19, 2018 | 91 | 2018 |
Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality RL Zuvich, LL Armstrong, SJ Bielinski, Y Bradford, CS Carlson, ... Genetic epidemiology 35 (8), 887-898, 2011 | 87 | 2011 |
Highly multiplexed quantitation of gene expression on single cells MH Dominguez, PK Chattopadhyay, S Ma, L Lamoreaux, A McDavid, ... Journal of immunological methods 391 (1-2), 133-145, 2013 | 86 | 2013 |
T cell–dependent affinity maturation and innate immune pathways differentially drive autoreactive B cell responses in rheumatoid arthritis DR Lu, AN McDavid, S Kongpachith, N Lingampalli, J Glanville, CH Ju, ... Arthritis & rheumatology 70 (11), 1732-1744, 2018 | 81 | 2018 |
Modeling bi-modality improves characterization of cell cycle on gene expression in single cells A McDavid, L Dennis, P Danaher, G Finak, M Krouse, A Wang, P Webster, ... PLoS computational biology 10 (7), e1003696, 2014 | 80 | 2014 |