mTORC1 couples cyst (e) ine availability with GPX4 protein synthesis and ferroptosis regulation Y Zhang, RV Swanda, L Nie, X Liu, C Wang, H Lee, G Lei, C Mao, ... Nature communications 12 (1), 1-14, 2021 | 391 | 2021 |
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis X Liu, L Nie, Y Zhang, Y Yan, C Wang, M Colic, K Olszewski, A Horbath, ... Nature cell biology 25 (3), 404-414, 2023 | 358 | 2023 |
Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition C Wang, G Wang, X Feng, P Shepherd, J Zhang, M Tang, Z Chen, ... Oncogene 38 (14), 2451-2463, 2019 | 116 | 2019 |
ATR inhibition potentiates ionizing radiation‐induced interferon response via cytosolic nucleic acid‐sensing pathways X Feng, A Tubbs, C Zhang, M Tang, S Sridharan, C Wang, D Jiang, D Su, ... The EMBO journal 39 (14), e104036, 2020 | 107 | 2020 |
Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics Z Chen, C Lei, C Wang, N Li, M Srivastava, M Tang, H Zhang, JM Choi, ... Nature communications 10 (1), 104, 2019 | 74 | 2019 |
Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association HL Huang, S Wang, MX Yin, L Dong, C Wang, W Wu, Y Lu, M Feng, C Dai, ... PLoS biology 11 (8), e1001620, 2013 | 68 | 2013 |
Interactomes of SARS‐CoV‐2 and human coronaviruses reveal host factors potentially affecting pathogenesis Z Chen, C Wang, X Feng, L Nie, M Tang, H Zhang, Y Xiong, SK Swisher, ... The EMBO journal 40 (17), e107776, 2021 | 60 | 2021 |
Importin α1 mediates Yorkie nuclear import via an N-terminal non-canonical nuclear localization signal S Wang, Y Lu, MX Yin, C Wang, W Wu, J Li, W Wu, L Ge, L Hu, Y Zhao, ... Journal of Biological Chemistry 291 (15), 7926-7937, 2016 | 41 | 2016 |
Replisome dynamics and their functional relevance upon DNA damage through the PCNA interactome M Srivastava, Z Chen, H Zhang, M Tang, C Wang, SY Jung, J Chen Cell reports 25 (13), 3869-3883. e4, 2018 | 39 | 2018 |
SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair H Zhang, Z Chen, Y Ye, Z Ye, D Cao, Y Xiong, M Srivastava, X Feng, ... Nucleic acids research 47 (19), 10181-10201, 2019 | 33 | 2019 |
Genome-wide CRISPR screen uncovers a synergistic effect of combining Haspin and Aurora kinase B inhibition M Huang, X Feng, D Su, G Wang, C Wang, M Tang, ... Oncogene 39 (21), 4312-4322, 2020 | 25 | 2020 |
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors X Feng, M Tang, M Dede, D Su, G Pei, D Jiang, C Wang, Z Chen, M Li, ... Science advances 8 (19), eabm6638, 2022 | 24 | 2022 |
CRISPR/CAS9-based DNA damage response screens reveal gene-drug interactions D Su, X Feng, M Colic, Y Wang, C Zhang, C Wang, M Tang, T Hart, ... DNA repair 87, 102803, 2020 | 24 | 2020 |
Genetic vulnerabilities upon inhibition of DNA damage response C Wang, M Tang, Z Chen, L Nie, S Li, Y Xiong, KA Szymonowicz, JM Park, ... Nucleic acids research 49 (14), 8214-8231, 2021 | 20 | 2021 |
Taiman acts as a coactivator of Yorkie in the Hippo pathway to promote tissue growth and intestinal regeneration C Wang, MX Yin, W Wu, L Dong, S Wang, Y Lu, J Xu, W Wu, S Li, Y Zhao, ... Cell discovery 2 (1), 1-15, 2016 | 19 | 2016 |
Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis C Wang, W Zhang, MX Yin, L Hu, P Li, J Xu, H Huang, S Wang, Y Lu, ... Nature Communications 6 (1), 6607, 2015 | 19 | 2015 |
C17orf53 is identified as a novel gene involved in inter-strand crosslink repair C Wang, Z Chen, D Su, M Tang, L Nie, H Zhang, X Feng, R Wang, X Shen, ... DNA repair 95, 102946, 2020 | 18 | 2020 |
Proteome-wide analysis reveals substrates of E3 ligase RNF146 targeted for degradation L Nie, C Wang, N Li, X Feng, N Lee, D Su, M Tang, F Yao, J Chen Molecular & Cellular Proteomics 19 (12), 2015-2030, 2020 | 16 | 2020 |
FOXK1 participates in DNA damage response by controlling 53BP1 function M Tang, X Feng, G Pei, M Srivastava, C Wang, Z Chen, S Li, H Zhang, ... Cell reports 32 (6), 2020 | 15 | 2020 |
Genome-wide CRISPR screens reveal cyclin C as synthetic survival target of BRCA2 M Tang, G Pei, D Su, C Wang, X Feng, M Srivastava, Z Chen, Z Zhao, ... Nucleic acids research 49 (13), 7476-7491, 2021 | 14 | 2021 |