Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia JL Moreno, P Miranda-Azpiazu, A García-Bea, J Younkin, M Cui, ... Science signaling 9 (410), ra5-ra5, 2016 | 122 | 2016 |
Plasma antioxidant capacity is reduced in Asperger syndrome M Parellada, C Moreno, K Mac-Dowell, JC Leza, M Giraldez, C Bailón, ... Journal of psychiatric research 46 (3), 394-401, 2012 | 91 | 2012 |
Evaluation of 5-HT2A and mGlu2/3 receptors in postmortem prefrontal cortex of subjects with major depressive disorder: effect of antidepressant treatment C Muguruza, P Miranda-Azpiazu, R Díez-Alarcia, B Morentin, ... Neuropharmacology 86, 311-318, 2014 | 78 | 2014 |
A novel dynamic multicellular co-culture system for studying individual blood-brain barrier cell types in brain diseases and cytotoxicity testing P Miranda-Azpiazu, S Panagiotou, G Jose, S Saha Scientific Reports 8 (1), 8784, 2018 | 47 | 2018 |
Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins A García-Bea, P Miranda-Azpiazu, C Muguruza, ... European Neuropsychopharmacology 29 (12), 1453-1463, 2019 | 42 | 2019 |
Imaging mutant huntingtin aggregates: development of a potential PET ligand L Liu, ME Prime, MR Lee, V Khetarpal, CJ Brown, PD Johnson, ... Journal of medicinal chemistry 63 (15), 8608-8633, 2020 | 34 | 2020 |
Identification and in vitro characterization of C05-01, a PBB3 derivative with improved affinity for alpha-synuclein P Miranda-Azpiazu, M Svedberg, M Higuchi, M Ono, Z Jia, D Sunnemark, ... Brain Research 1749, 147131, 2020 | 25 | 2020 |
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases R Smith, F Capotosti, M Schain, T Ohlsson, E Vokali, J Molette, ... Nature communications 14 (1), 6750, 2023 | 24 | 2023 |
Substituted conformationally restricted guanidine derivatives: Probing the α2-adrenoceptors’ binding pocket M McMullan, A García-Bea, P Miranda-Azpiazu, LF Callado, I Rozas European Journal of Medicinal Chemistry 123, 48-57, 2016 | 21 | 2016 |
Differential brain ADRA2A and ADRA2C gene expression and epigenetic regulation in schizophrenia. Effect of antipsychotic drug treatment I Brocos-Mosquera, P Miranda-Azpiazu, C Muguruza, V Corzo-Monje, ... Translational Psychiatry 11 (1), 643, 2021 | 17 | 2021 |
Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue:[35S] GTPγS binding assays combined with immunoprecipitation R Diez-Alarcia, Y Odagaki, P Miranda-Azpiazu, AM Gabilondo, JJ Meana, ... Pharmacological Reports 73 (4), 1079-1095, 2021 | 8 | 2021 |
Development of 11C-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR) S Nag, P Miranda-Azpiazu, Z Jia, P Datta, R Arakawa, MM Moein, Z Yang, ... ACS Chemical Neuroscience 13 (3), 352-362, 2022 | 7 | 2022 |
P. 1. g. 022 Hallucinogenic and non-hallucinogenic 5-HT2A receptor agonists induce distinct patterns of G protein coupling in postmortem human brain P Miranda-Azpiazu, R Díez-Alarcia, A García-Bea, J González-Maeso, ... European Neuropsychopharmacology, S201, 2013 | 5 | 2013 |
Di-aryl guanidinium derivatives: Towards improved α2-Adrenergic affinity and antagonist activity M McMullan, B Kelly, HB Mihigo, AP Keogh, F Rodriguez, ... European Journal of Medicinal Chemistry 209, 112947, 2021 | 4 | 2021 |
Synthesis, 3H‐labelling and in vitro evaluation of a substituted dipiperidine alcohol as a potential ligand for chemokine receptor 2 M Artelsmair, P Miranda‐Azpiazu, L Kingston, J Bergare, M Schou, ... Journal of Labelled Compounds and Radiopharmaceuticals 62 (6), 265-279, 2019 | 3 | 2019 |
Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain I Muneta‐Arrate, P Miranda‐Azpiazu, I Horrillo, R Diez‐Alarcia, JJ Meana British Journal of Pharmacology, 2024 | 2 | 2024 |
Synthesis and Preclinical Evaluation of [11C]AZ11895530 for PET Imaging of the Serotonin 1A Receptor K Dahl, P Johnström, A Forsberg-Morén, B Gustafsson, ... ACS Chemical Neuroscience 13 (14), 2078-2083, 2022 | 2 | 2022 |
Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects J DelaCuesta-Barrutia, O Martínez-Peula, G Rivero, JA Santas-Martín, ... Translational Psychiatry 14 (1), 113, 2024 | 1 | 2024 |
A Novel Dynamic Human In Vitro Model for Studying the Blood–Brain Barrier P Miranda-Azpiazu, S Saha The Blood-Brain Barrier: Methods and Protocols, 157-173, 2022 | 1 | 2022 |
P. 3. a. 001 Selective up-regulation of serotonin 5-HT2A receptor coupling to Gαi1-proteins in postmortem brain of subjects with schizophrenia JJ Meana, P Miranda-Azpiazu, A Garcia-Bea, C Muguruza, LF Callado, ... European Neuropsychopharmacology, S483-S484, 2014 | 1 | 2014 |