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Wanqing Li
Wanqing Li
在 gene.com 的电子邮件经过验证
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年份
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut
A Bell, J Brunt, E Crost, L Vaux, R Nepravishta, CD Owen, D Latousakis, ...
Nature microbiology 4 (12), 2393-2404, 2019
1152019
Strategies for chemoenzymatic synthesis of carbohydrates
W Li, JB McArthur, X Chen
Carbohydrate research 472, 86-97, 2019
812019
Cobalt-catalyzed decarboxylative 2-benzoylation of oxazoles and thiazoles with α-oxocarboxylic acids
K Yang, X Chen, Y Wang, W Li, AA Kadi, HK Fun, H Sun, Y Zhang, G Li, ...
The Journal of organic chemistry 80 (21), 11065-11072, 2015
732015
A chemical biology solution to problems with studying biologically important but unstable 9-O-acetyl sialic acids
Z Khedri, A Xiao, H Yu, CS Landig, W Li, S Diaz, BR Wasik, CR Parrish, ...
ACS chemical biology 12 (1), 214-224, 2017
432017
A Diazido Mannose Analogue as a Chemoenzymatic Synthon for Synthesizing Di‐N‐acetyllegionaminic Acid‐Containing Glycosides
A Santra, A Xiao, H Yu, W Li, Y Li, L Ngo, JB McArthur, X Chen
Angewandte Chemie 130 (11), 2979-2983, 2018
312018
Chemoenzymatic synthesis of Neu5Ac9NAc-containing α2–3-and α2–6-linked sialosides and their use for sialidase substrate specificity studies
W Li, A Xiao, Y Li, H Yu, X Chen
Carbohydrate research 451, 51-58, 2017
312017
Are sialic acids involved in COVID-19 pathogenesis?
C Dhar, A Sasmal, S Diaz, A Verhagen, H Yu, W Li, X Chen, A Varki
Glycobiology 31 (9), 1068-1071, 2021
242021
Reversible O-Acetyl Migration within the Sialic Acid Side Chain and Its Influence on Protein Recognition
Y Ji, A Sasmal, W Li, L Oh, S Srivastava, AA Hargett, BR Wasik, H Yu, ...
ACS chemical biology 16 (10), 1951-1960, 2021
222021
Facile chemoenzymatic synthesis of Lewis a (Lea) antigen in gram-scale and sialyl Lewis a (sLea) antigens containing diverse sialic acid forms
N Tasnima, H Yu, X Yan, W Li, A Xiao, X Chen
Carbohydrate research 472, 115-121, 2019
222019
A combined NMR, MD and DFT conformational analysis of 9-O-acetyl sialic acid-containing GM3 ganglioside glycan and its 9-N-acetyl mimic
W Li, MD Battistel, H Reeves, L Oh, H Yu, X Chen, LP Wang, ...
Glycobiology 30 (10), 787-801, 2020
202020
Triazole-linked transition state analogs as selective inhibitors against V. cholerae sialidase
TJ Slack, W Li, D Shi, JB McArthur, G Zhao, Y Li, A Xiao, Z Khedri, H Yu, ...
Bioorganic & medicinal chemistry 26 (21), 5751-5757, 2018
202018
Sialidase-catalyzed one-pot multienzyme (OPME) synthesis of sialidase transition-state analogue inhibitors
A Xiao, Y Li, X Li, A Santra, H Yu, W Li, X Chen
ACS catalysis 8 (1), 43-47, 2018
202018
Streptococcus pneumoniae Sialidase SpNanB-Catalyzed One-Pot Multienzyme (OPME) Synthesis of 2,7-Anhydro-Sialic Acids as Selective Sialidase Inhibitors
A Xiao, TJ Slack, Y Li, D Shi, H Yu, W Li, Y Liu, X Chen
The Journal of organic chemistry 83 (18), 10798-10804, 2018
192018
9-Azido-9-deoxy-2, 3-difluorosialic acid as a subnanomolar inhibitor against bacterial sialidases
W Li, A Santra, H Yu, TJ Slack, MM Muthana, D Shi, Y Liu, X Chen
The Journal of organic chemistry 84 (11), 6697-6708, 2019
182019
Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/β-catenin signaling
S Hansen, Y Zhang, S Hwang, A Nabhan, W Li, J Fuhrmann, ...
Proceedings of the National Academy of Sciences 119 (46), e2207327119, 2022
162022
L. pneumophila CMP-5, 7-di-N-acetyllegionaminic acid synthetase (LpCLS)-involved chemoenzymatic synthesis of sialosides and analogues
JB McArthur, A Santra, W Li, AS Kooner, Z Liu, H Yu, X Chen
Organic & biomolecular chemistry 18 (4), 738-744, 2020
112020
A substrate tagging and two-step enzymatic reaction strategy for large-scale synthesis of 2, 7-anhydro-sialic acid
W Li, T Ghosh, Y Bai, A Santra, A Xiao, X Chen
Carbohydrate research 479, 41-47, 2019
112019
O-Acetyl Migration within the Sialic Acid Side Chain: A Mechanistic Study Using the Ab Initio Nanoreactor
L Oh, Y Ji, W Li, A Varki, X Chen, LP Wang
Biochemistry 61 (18), 2007-2013, 2022
52022
Sialidase inhibitors and preparation thereof
X Chen, A Xiao, W Li, LI Xixuan, Y Li, T Slack
US Patent 11,325,936, 2022
2022
N-acetylated sialic acids and related sialosides
X Chen, A Xiao, A Kooner, A Santra, A Varki, H Yu, W Lee-Ping, W Li
US Patent App. 17/491,518, 2022
2022
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