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Sylvain Meloche
Sylvain Meloche
Institute of Research in Immunology and Cancer, Université de Montréal
在 umontreal.ca 的电子邮件经过验证 - 首页
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引用次数
引用次数
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The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1-to S-phase transition
S Meloche, J Pouysségur
Oncogene 26 (22), 3227-3239, 2007
13682007
Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.
G Pages, P Lenormand, G L'Allemain, JC Chambard, S Meloche, ...
Proceedings of the National Academy of Sciences 90 (18), 8319-8323, 1993
12901993
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
T Kunath, MK Saba-El-Leil, M Almousailleakh, J Wray, S Meloche, ...
Oxford University Press for The Company of Biologists Limited 134 (16), 2895 …, 2007
9372007
An essential function of the mitogen‐activated protein kinase Erk2 in mouse trophoblast development
MK Saba‐El‐Leil, FDJ Vella, B Vernay, L Voisin, L Chen, N Labrecque, ...
EMBO reports 4 (10), 964-968, 2003
4712003
Roles of the Candida albicansMitogen-Activated Protein Kinase Homolog, Cek1p, in Hyphal Development and Systemic Candidiasis
C Csank, K Schröppel, E Leberer, D Harcus, O Mohamed, S Meloche, ...
Infection and immunity 66 (6), 2713-2721, 1998
4491998
Atypical mitogen-activated protein kinases: structure, regulation and functions
P Coulombe, S Meloche
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (8), 1376-1387, 2007
4402007
Biphasic and synergistic activation of p44mapk (ERK1) by growth factors: correlation between late phase activation and mitogenicity.
S Meloche, K Seuwen, G Pages, J Pouyssegur
Molecular Endocrinology 6 (5), 845-854, 1992
3781992
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis
G Rodier, A Montagnoli, L Di Marcotullio, P Coulombe, GF Draetta, ...
The EMBO journal, 2001
3452001
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis
L Yen, XL You, AE Al Moustafa, G Batist, NE Hynes, S Mader, S Meloche, ...
Oncogene 19 (31), 3460-3469, 2000
3212000
Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA
F Charron, G Tsimiklis, M Arcand, L Robitaille, Q Liang, JD Molkentin, ...
Genes & development 15 (20), 2702-2719, 2001
3142001
Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo
NH Purcell, BJ Wilkins, A York, MK Saba-El-Leil, S Meloche, J Robbins, ...
Proceedings of the National Academy of Sciences 104 (35), 14074-14079, 2007
3052007
MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo
DJ Lips, OF Bueno, BJ Wilkins, NH Purcell, RA Kaiser, JN Lorenz, ...
Circulation 109 (16), 1938-1941, 2004
2972004
Coordinate, biphasic activation of p44 mitogen-activated protein kinase and S6 kinase by growth factors in hamster fibroblasts. Evidence for thrombin-induced signals different …
C Kahan, K Seuwen, S Meloche, J Pouyssegur
Journal of Biological Chemistry 267 (19), 13369-13375, 1992
2971992
From basic research to clinical development of MEK1/2 inhibitors for cancer therapy
C Frémin, S Meloche
Journal of hematology & oncology 3, 1-11, 2010
2962010
Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth
I Kehat, J Davis, M Tiburcy, F Accornero, MK Saba-El-Leil, M Maillet, ...
Circulation research 108 (2), 176-183, 2011
2942011
Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability
R Lin, P Beauparlant, C Makris, S Meloche, J Hiscott
Molecular and Cellular Biology, 1996
2651996
ERKs in cancer: friends or foes?
X Deschênes-Simard, F Kottakis, S Meloche, G Ferbeyre
Cancer research 74 (2), 412-419, 2014
2522014
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme
DF Ceccarelli, X Tang, B Pelletier, S Orlicky, W Xie, V Plantevin, ...
Cell 145 (7), 1075-1087, 2011
2482011
The IKK-related kinases: from innate immunity to oncogenesis
JF Clément, S Meloche, MJ Servant
Cell research 18 (9), 889-899, 2008
2322008
Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals
D Zhang, M Bar-Eli, S Meloche, P Brodt
Journal of Biological Chemistry 279 (19), 19683-19690, 2004
2252004
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