Delivery of therapeutic oligonucleotides with cell penetrating peptides P Boisguérin, S Deshayes, MJ Gait, L O'Donovan, C Godfrey, CA Betts, ... Advanced drug delivery reviews 87, 52-67, 2015 | 273 | 2015 |
Comparison of cellular uptake using 22 CPPs in 4 different cell lines J Mueller, I Kretzschmar, R Volkmer, P Boisguerin Bioconjugate chemistry 19 (12), 2363-2374, 2008 | 260 | 2008 |
Quantification of PDZ domain specificity, prediction of ligand affinity and rational design of super-binding peptides U Wiedemann, P Boisguerin, R Leben, D Leitner, G Krause, K Moelling, ... Journal of molecular biology 343 (3), 703-718, 2004 | 190 | 2004 |
The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling PR Cushing, A Fellows, D Villone, P Boisguerin, DR Madden Biochemistry 47 (38), 10084-10098, 2008 | 141 | 2008 |
Computational design of a PDZ domain peptide inhibitor that rescues CFTR activity KE Roberts, PR Cushing, P Boisguerin, DR Madden, BR Donald PLoS computational biology 8 (4), e1002477, 2012 | 135 | 2012 |
An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies P Boisguerin, R Leben, B Ay, G Radziwill, K Moelling, L Dong, ... Chemistry & biology 11 (4), 449-459, 2004 | 113 | 2004 |
Cellular trafficking determines the exon skipping activity of Pip6a-PMO in mdx skeletal and cardiac muscle cells T Lehto, A Castillo Alvarez, S Gauck, MJ Gait, T Coursindel, MJA Wood, ... Nucleic Acids Research 42 (5), 3207-3217, 2014 | 97 | 2014 |
A stabilizing influence: CAL PDZ inhibition extends the half‐life of ΔF508‐CFTR PR Cushing, L Vouilleme, M Pellegrini, P Boisguerin, DR Madden Angewandte Chemie 122 (51), 10103-10107, 2010 | 86 | 2010 |
A retro-inverso cell-penetrating peptide for siRNA delivery A Vaissière, G Aldrian, K Konate, MF Lindberg, C Jourdan, A Telmar, ... Journal of nanobiotechnology 15 (1), 1-18, 2017 | 69 | 2017 |
Discovery of low‐molecular‐weight ligands for the AF6 PDZ domain M Joshi, C Vargas, P Boisguerin, A Diehl, G Krause, P Schmieder, ... Angewandte Chemie 118 (23), 3874-3879, 2006 | 62 | 2006 |
Engineering peptide inhibitors to overcome PDZ binding promiscuity L Vouilleme, PR Cushing, R Volkmer, DR Madden, P Boisguerin Angewandte Chemie 122 (51), 10108-10112, 2010 | 57 | 2010 |
Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling S Eulitz, F Sauer, MC Pelissier, P Boisguerin, S Molt, J Schuld, Z Orfanos, ... Molecular biology of the cell 24 (20), 3215-3226, 2013 | 48 | 2013 |
PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo G Aldrian, A Vaissière, K Konate, Q Seisel, E Vivès, F Fernandez, ... Journal of Controlled Release 256, 79-91, 2017 | 46 | 2017 |
Systemic delivery of BH4 anti-apoptotic peptide using CPPs prevents cardiac ischemia–reperfusion injuries in vivo P Boisguerin, C Redt-Clouet, A Franck-Miclo, S Licheheb, J Nargeot, ... Journal of controlled release 156 (2), 146-153, 2011 | 45 | 2011 |
Characterization of a putative phosphorylation switch: adaptation of SPOT synthesis to analyze PDZ domain regulation mechanisms P Boisguerin, B Ay, G Radziwill, RD Fritz, K Moelling, R Volkmer ChemBioChem 8 (18), 2302-2307, 2007 | 45 | 2007 |
Stereochemical preferences modulate affinity and selectivity among five PDZ domains that bind CFTR: comparative structural and sequence analyses JF Amacher, PR Cushing, L Brooks, P Boisguerin, DR Madden Structure 22 (1), 82-93, 2014 | 43 | 2014 |
Regulation of c‐Src by binding to the PDZ domain of AF‐6 G Radziwill, A Weiss, J Heinrich, M Baumgartner, P Boisguerin, K Owada, ... The EMBO journal 26 (11), 2633-2644, 2007 | 43 | 2007 |
Peptide-based nanoparticles to rapidly and efficiently “Wrap’n roll” siRNA into cells K Konate, M Dussot, G Aldrian, A Vaissière, V Viguier, IF Neira, ... Bioconjugate Chemistry 30 (3), 592-603, 2018 | 38 | 2018 |
PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ B Jonik-Nowak, T Menneteau, D Fesquet, V Baldin, C Bonne-Andrea, ... Proceedings of the National Academy of Sciences 115 (28), E6477-E6486, 2018 | 35 | 2018 |
CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis M Mastny, A Heuck, R Kurzbauer, A Heiduk, P Boisguerin, R Volkmer, ... Cell 155 (3), 647-658, 2013 | 35 | 2013 |