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Eloise Keeling
Eloise Keeling
在 soton.ac.uk 的电子邮件经过验证
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引用次数
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Impaired cargo clearance in the retinal pigment epithelium (RPE) underlies irreversible blinding diseases
E Keeling, AJ Lotery, DA Tumbarello, JA Ratnayaka
Cells 7 (2), 16, 2018
722018
The complexities underlying age-related macular degeneration: could amyloid beta play an important role?
SA Lynn, E Keeling, R Munday, G Gabha, H Griffiths, AJ Lotery, ...
Neural regeneration research 12 (4), 538-548, 2017
472017
Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE
SA Lynn, G Ward, E Keeling, JA Scott, AJ Cree, DA Johnston, A Page, ...
Tissue and Cell 49 (4), 447-460, 2017
292017
The Alzheimer's-related amyloid beta peptide is internalised by R28 neuroretinal cells and disrupts the microtubule associated protein 2 (MAP-2)
G Taylor-Walker, SA Lynn, E Keeling, R Munday, DA Johnston, A Page, ...
Experimental eye research 153, 110-121, 2016
212016
Oxidative stress and dysfunctional intracellular traffic linked to an unhealthy diet results in impaired cargo transport in the retinal pigment epithelium (RPE)
E Keeling, DS Chatelet, DA Johnston, A Page, DA Tumbarello, AJ Lotery, ...
Molecular nutrition & food research 63 (15), 1800951, 2019
192019
A lasered mouse model of retinal degeneration displays progressive outer retinal pathology providing insights into early geographic atrophy
P Ibbett, SV Goverdhan, E Pipi, JK Chouhan, E Keeling, EM Angus, ...
Scientific Reports 9 (1), 7475, 2019
192019
3D-reconstructed retinal pigment epithelial cells provide insights into the anatomy of the outer retina
E Keeling, DS Chatelet, NYT Tan, F Khan, R Richards, T Thisainathan, ...
International journal of molecular sciences 21 (21), 8408, 2020
182020
A convenient protocol for establishing a human cell culture model of the outer retina.
SA Lynn, E Keeling, JM Dewing, DA Johnston, A Page, AJ Cree, ...
F1000Research 7, 2018
182018
Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function
SA Lynn, DA Johnston, JA Scott, R Munday, RS Desai, E Keeling, ...
Cells 10 (2), 413, 2021
152021
A High Fat “Western‐style” Diet Induces AMD‐Like Features in Wildtype Mice
E Keeling, SA Lynn, YM Koh, JA Scott, A Kendall, M Gatherer, A Page, ...
Molecular Nutrition & Food Research 66 (11), 2100823, 2022
112022
An in-vitro cell model of intracellular protein aggregation provides insights into RPE stress associated with retinopathy
E Keeling, AJ Culling, DA Johnston, DS Chatelet, A Page, DA Tumbarello, ...
International journal of molecular sciences 21 (18), 6647, 2020
82020
Impaired cargo clearance in the retinal pigment epithelium (RPE) underlies irreversible blinding diseases. Cells 7
E Keeling, AJ Lotery, DA Tumbarello, JA Ratnayaka
E16, 2018
52018
Serial block face scanning electron microscopy reveals novel organizational details of the retinal pigment epithelium
JA Ratnayaka, E Keeling
Neural Regeneration Research 17 (3), 569-571, 2022
32022
Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism
A Sanchez-Bretano, E Keeling, JA Scott, SA Lynn, SP Soundara-Pandi, ...
Scientific Reports 13 (1), 17173, 2023
12023
Study of Intracellular Cargo Trafficking and Co-localization in the Phagosome and Autophagy-Lysosomal Pathways of Retinal Pigment Epithelium (RPE) Cells
JA Ratnayaka, E Keeling, DS Chatelet
Imaging and Tracking Stem Cells: Methods and Protocols, 167-182, 2020
12020
Lysosomal impairment in the Retinal Pigment Epithelium (RPE)-a pathway of damage in the ageing retina
E Keeling, DA Johnston, DS Chatelet, D Tumbarello, A Lotery, ...
Investigative Ophthalmology & Visual Science 59 (9), 4487-4487, 2018
12018
Eyetracking-enhanced VEP for nystagmus
P Carter, F Shawkat, J Self, H Lee, E Keeling, M Dunn
Investigative Ophthalmology & Visual Science 64 (8), 43-43, 2023
2023
Intraluminal acidity plays a key role in the function of lysosomes in RPE cells
RD Miller, SA Lynn, E Keeling, C Ellis, D Chatelet, DA Johnston, ...
Investigative Ophthalmology & Visual Science 64 (8), 3891-3891, 2023
2023
Use of a handheld electrophysiology device (RETeval, LKC) to identify visual pathway decussation defects
E Keeling, P Carter, F Shawkat, H Lee, J Self
Investigative Ophthalmology & Visual Science 64 (8), 5325-5325, 2023
2023
Dataset in support of the publication'Human equivalent doses of L-DOPA rescues retinal morphology and visual function in a murine model of albinism'
E Keeling, H Lee
University of Southampton, 2023
2023
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