Antibacterial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-diamines KS Van Horn, WN Burda, R Fleeman, LN Shaw, R Manetsch Journal of Medicinal Chemistry 57 (7), 3075-3093, 2014 | 109 | 2014 |
Combinatorial libraries as a tool for the discovery of novel, broad-spectrum antibacterial agents targeting the ESKAPE pathogens R Fleeman, TM LaVoi, RG Santos, A Morales, A Nefzi, GS Welmaker, ... Journal of medicinal chemistry 58 (8), 3340-3355, 2015 | 98 | 2015 |
Darwinolide, a New Diterpene Scaffold That Inhibits Methicillin-Resistant Staphylococcus aureus Biofilm from the Antarctic Sponge Dendrilla membranosa JL von Salm, CG Witowski, RM Fleeman, JB McClintock, CD Amsler, ... Organic letters 18 (11), 2596-2599, 2016 | 63 | 2016 |
Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities N Bionda, RM Fleeman, C De La Fuente-Núñez, MC Rodriguez, ... European journal of medicinal chemistry 108, 354-363, 2016 | 58 | 2016 |
The “PepSAVI-MS” pipeline for natural product bioactive peptide discovery CL Kirkpatrick, CA Broberg, EN McCool, WJ Lee, A Chao, EW McConnell, ... Analytical chemistry 89 (2), 1194-1201, 2017 | 45 | 2017 |
Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae RM Fleeman, LA Macias, JS Brodbelt, BW Davies Proceedings of the National Academy of Sciences 117 (44), 27620-27626, 2020 | 44 | 2020 |
Identification of a novel polyamine scaffold with potent efflux pump inhibition activity toward multi-drug resistant bacterial pathogens RM Fleeman, G Debevec, K Antonen, JL Adams, RG Santos, ... Frontiers in microbiology 9, 1301, 2018 | 43 | 2018 |
Characterizing the Antimicrobial Activity of N2,N4-Disubstituted Quinazoline-2,4-Diamines toward Multidrug-Resistant Acinetobacter baumannii R Fleeman, KS Van Horn, MM Barber, WN Burda, DL Flanigan, ... Antimicrobial Agents and Chemotherapy 61 (6), 10.1128/aac. 00059-17, 2017 | 32 | 2017 |
Exploitation of mangrove endophytic fungi for infectious disease drug discovery DH Demers, MA Knestrick, R Fleeman, R Tawfik, A Azhari, A Souza, ... Marine Drugs 16 (10), 376, 2018 | 27 | 2018 |
Effect of Ester to Amide or N‐Methylamide Substitution on Bacterial Membrane Depolarization and Antibacterial Activity of Novel Cyclic Lipopeptides N Bionda, RM Fleeman, LN Shaw, P Cudic ChemMedChem 8 (8), 1394-1402, 2013 | 21 | 2013 |
Identification of 5, 6-dihydroimidazo [2, 1-b] thiazoles as a new class of antimicrobial agents Y Li, N Bionda, R Fleeman, H Wang, A Ozawa, RA Houghten, L Shaw Bioorganic & medicinal chemistry 24 (21), 5633-5638, 2016 | 18 | 2016 |
Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic JR Randall, G Davidson, RM Fleeman, SA Acosta, IM Riddington, TJ Cole, ... IScience 25 (1), 2022 | 8 | 2022 |
BIS-cyclic guanidine compound compositions, methods of use and treatment thereof LN Shaw, RM Fleeman, RA Houghten, MA Giulianotti, RG Santos, A Nefzi US Patent 9,782,388, 2017 | 6 | 2017 |
Investigating Klebsiella pneumoniae biofilm preservation for scanning electron microscopy RM Fleeman, M Mikesh, BW Davies Access Microbiology 5 (2), 000470. v3, 2023 | 4 | 2023 |
Polyproline peptide aggregation with Klebsiella pneumoniae extracellular polysaccharides exposes biofilm associated bacteria RM Fleeman, BW Davies Microbiology Spectrum 10 (2), e02027-21, 2022 | 4 | 2022 |
Bis-cyclic guanidine compound compositions, methods of use and treatment thereof LN Shaw, RM Fleeman, RA Houghten, MA Giulianotti, RG Santos, A Nefzi US Patent 10,052,309, 2018 | 4 | 2018 |
Repurposing inhibitors of phosphoinositide 3-kinase as adjuvant therapeutics for bacterial infections R Fleeman Frontiers in Antibiotics 2, 1135485, 2023 | 2 | 2023 |
Antimicrobials from an epigenetics based fungal metabolite screening program DH Demers, BJ Baker, A Azhari, RM Fleeman, DE Kyle, LN Shaw US Patent 10,144,719, 2018 | 2 | 2018 |
Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens R Fleeman University of South Florida, 2017 | 2 | 2017 |
Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms L De los Santos, RL Beckman, C DeBarro, JE Keener, MDT Torres, ... Cell Reports Physical Science 5 (3), 2024 | 1 | 2024 |