| Lactic acid and an acidic tumor microenvironment suppress anticancer immunity JX Wang, SYC Choi, X Niu, N Kang, H Xue, J Killam, Y Wang International journal of molecular sciences 21 (21), 8363, 2020 | 277 | 2020 |
| Binding of released Bim to Mcl-1 is a mechanism of intrinsic resistance to ABT-199 which can be overcome by combination with daunorubicin or cytarabine in AML cells X Niu, J Zhao, J Ma, C Xie, H Edwards, G Wang, JT Caldwell, S Xiang, ... Clinical Cancer Research 22 (17), 4440-4451, 2016 | 222 | 2016 |
| Inhibition of Mcl-1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells DA Luedtke, X Niu, Y Pan, J Zhao, S Liu, H Edwards, K Chen, H Lin, ... Signal transduction and targeted therapy 2 (1), 1-9, 2017 | 146 | 2017 |
| Acute myeloid leukemia cells harboring MLL fusion genes or with the acute promyelocytic leukemia phenotype are sensitive to the Bcl-2-selective inhibitor ABT-199 X Niu, G Wang, Y Wang, JT Caldwell, H Edwards, C Xie, JW Taub, C Li, ... Leukemia 28 (7), 1557-1560, 2014 | 110 | 2014 |
| Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells J Zhao, X Niu, X Li, H Edwards, G Wang, Y Wang, JW Taub, H Lin, Y Ge Oncotarget 7 (23), 34785, 2016 | 46 | 2016 |
| Synergistic antitumor interactions between MK-1775 and panobinostat in preclinical models of pancreatic cancer G Wang, X Niu, W Zhang, JT Caldwell, H Edwards, W Chen, JW Taub, ... Cancer letters 356 (2), 656-668, 2015 | 41 | 2015 |
| Synthesis and antileukemic activities of piperlongumine and HDAC inhibitor hybrids against acute myeloid leukemia cells Y Liao, X Niu, B Chen, H Edwards, L Xu, C Xie, H Lin, L Polin, JW Taub, ... Journal of medicinal chemistry 59 (17), 7974-7990, 2016 | 40 | 2016 |
| Combination of AZD2281 (Olaparib) and GX15-070 (Obatoclax) results in synergistic antitumor activities in preclinical models of pancreatic cancer S Chen, G Wang, X Niu, J Zhao, W Tan, H Wang, L Zhao, Y Ge Cancer Letters 348 (1-2), 20-28, 2014 | 32 | 2014 |
| Synergistic anti-leukemic interactions between ABT-199 and panobinostat in acute myeloid leukemia ex vivo J Schwartz, X Niu, E Walton, L Hurley, H Lin, H Edwards, JW Taub, ... American journal of translational research 8 (9), 3893, 2016 | 30 | 2016 |
| Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia X Niu, K Rothe, M Chen, S Grasedieck, R Li, SE Nam, X Zhang, ... Blood, The Journal of the American Society of Hematology 137 (26), 3641-3655, 2021 | 29 | 2021 |
| Expression and purification of recombinant NRL-Hsp90α and Cdc37-CRL proteins for in vitro Hsp90/Cdc37 inhibitors screening J He, X Niu, C Hu, H Zhang, Y Guo, Y Ge, G Wang, Y Jiang Protein Expression and Purification 92 (1), 119-127, 2013 | 9 | 2013 |
| Antitumor activity and mechanism of resistance of the novel HDAC and PI3K dual inhibitor CUDC-907 in pancreatic cancer S Liu, S Zhao, Y Dong, T Wang, X Niu, L Zhao, G Wang Cancer Chemotherapy and Pharmacology 87, 415-423, 2021 | 8 | 2021 |
| Targeting the GAS6/AXL pathway with a newly developed AXL-selective inhibitor SLC-0211 for the treatment of acute myeloid leukemia X Niu, K Roche, M Chen, H Zhang, J Yan, Y Ge, Z Zhang, X Jiang Blood 130, 2640, 2017 | 1 | 2017 |
| Binding of released Bim to Mcl-1 is responsible for resistance to ABT-199 which can be overcome by combination with daunorubicin or cytarabine in acute myeloid leukemia cells X Niu, J Zhao, J Ma, C Xie, H Edwards, G Wang, JT Caldwell, R Chu, ... Blood 126 (23), 1265, 2015 | 1 | 2015 |
| Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells J Zhao, X Niu, H Edwards, Y Wang, JW Taub, H Lin, Y Ge Blood 126 (23), 2469, 2015 | 1 | 2015 |
| Combination therapy for treating blood cancer Z Zhang, X Jiang, K Rothe, X Niu US Patent App. 17/276,459, 2022 | | 2022 |
| Targeting AXL Kinase Sensitizes Acute Myeloid Leukemia Stem and Progenitor Cells to Venetoclax Treatment K Rothe, X Niu, M Chen, R Li, S Nam, X Zhang, G Novakovskiy, Y Ahn, ... Blood 136, 20, 2020 | | 2020 |
| 3125–COMBINING VENETOCLAX TREATMENT WITH AXL KINASE INHIBITION TARGETS CANCER STEM AND PROGENITOR CELLS IN ACUTE MYELOID LEUKEMIA K Rothe, Y Ahn, M Chen, Y Ge, X Jiang, S Lai, R Li, H Liu, S Nam, X Niu, ... Experimental Hematology 88, S76-S77, 2020 | | 2020 |
| CUDC-907 S Liu, S Zhao, Y Dong, T Wang, X Niu, L Zhao, G Wang | | |
