| Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition L von Kleist, W Stahlschmidt, H Bulut, K Gromova, D Puchkov, ... Cell 146 (3), 471-484, 2011 | 585 | 2011 |
| A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication S Hattori, N Higashi-Kuwata, H Hayashi, SR Allu, J Raghavaiah, H Bulut, ... Nature Communications 12 (1), 668, 2021 | 153 | 2021 |
| Disruption of adaptor protein 2μ (AP‐2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing SY Jung, T Maritzen, C Wichmann, Z Jing, A Neef, NH Revelo, ... The EMBO journal 34 (21), 2686-2702, 2015 | 114 | 2015 |
| Disruption of endocytosis through chemical inhibition of clathrin heavy chain function W Dejonghe, I Sharma, B Denoo, S De Munck, Q Lu, K Mishev, H Bulut, ... Nature chemical biology 15 (6), 641-649, 2019 | 86 | 2019 |
| Design and development of highly potent HIV-1 protease inhibitors with a crown-like oxotricyclic core as the P2-ligand to combat multidrug-resistant HIV variants AK Ghosh, KV Rao, PR Nyalapatla, HL Osswald, CD Martyr, M Aoki, ... Journal of medicinal chemistry 60 (10), 4267-4278, 2017 | 78 | 2017 |
| GRL-0920, an indole chloropyridinyl ester, completely blocks SARS-CoV-2 infection S Hattori, N Higshi-Kuwata, J Raghavaiah, D Das, H Bulut, DA Davis, ... MBio 11 (4), 10.1128/mbio. 01833-20, 2020 | 54 | 2020 |
| A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency M Aoki, H Hayashi, KV Rao, D Das, N Higashi-Kuwata, H Bulut, ... Elife 6, e28020, 2017 | 48 | 2017 |
| Crystal structures of two solute receptors for L-cystine and L-cysteine, respectively, of the human pathogen Neisseria gonorrhoeae H Bulut, S Moniot, A Licht, F Scheffel, S Gathmann, W Saenger, ... Journal of molecular biology 415 (3), 560-572, 2012 | 45 | 2012 |
| Does Mycoplasma sp. play role in small cell lung cancer? M Pehlivan, G Itirli, H Onay, H Bulut, M Koyuncuoglu, S Pehlivan Lung Cancer 45 (1), 129-130, 2004 | 34 | 2004 |
| Identification of a novel long-acting 4’-modified nucleoside reverse transcriptase inhibitor against HBV N Higashi-Kuwata, S Hayashi, H Kumamoto, H Ogata-Aoki, D Das, ... Journal of hepatology 74 (5), 1075-1086, 2021 | 29 | 2021 |
| Crystal structures of the solute receptor GacH of Streptomyces glaucescens in complex with acarbose and an acarbose homolog: comparison with the acarbose-loaded maltose-binding … A Vahedi-Faridi, A Licht, H Bulut, F Scheffel, S Keller, UF Wehmeier, ... Journal of molecular biology 397 (3), 709-723, 2010 | 28 | 2010 |
| Lack of association between catalase gene polymorphism (T/C exon 9) and susceptibility to vitiligo in a Turkish population H Bulut, M Pehlivan, S Alper, AG Tomatır, H Onay, SE Yüksel, F Özkinay Genetics and Molecular Research, 2011 | 24 | 2011 |
| Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for β-D-galactopyranose A Licht, H Bulut, F Scheffel, O Daumke, UF Wehmeier, W Saenger, ... Journal of molecular biology 406 (1), 92-105, 2011 | 22 | 2011 |
| Regulation of the dimerization and activity of SARS-CoV-2 main protease through reversible glutathionylation of cysteine 300 DA Davis, H Bulut, P Shrestha, A Yaparla, HK Jaeger, S Hattori, ... Mbio 12 (4), 10.1128/mbio. 02094-21, 2021 | 18 | 2021 |
| Identification of SARS-CoV-2 Mpro inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2 N Higashi-Kuwata, K Tsuji, H Hayashi, H Bulut, M Kiso, M Imai, ... Nature Communications 14 (1), 1076, 2023 | 17 | 2023 |
| A Modified P1 Moiety Enhances In Vitro Antiviral Activity against Various Multidrug-Resistant HIV-1 Variants and In Vitro Central Nervous System Penetration … M Amano, PM Salcedo-Gómez, R Zhao, RS Yedidi, D Das, H Bulut, ... Antimicrobial Agents and Chemotherapy 60 (12), 7046-7059, 2016 | 16 | 2016 |
| Halogen bond interactions of novel HIV-1 protease inhibitors (PI)(GRL-001-15 and GRL-003-15) with the flap of protease are critical for their potent activity against wild-type … S Hattori, H Hayashi, H Bulut, KV Rao, PR Nyalapatla, K Hasegawa, ... Antimicrobial Agents and Chemotherapy 63 (6), 10.1128/aac. 02635-18, 2019 | 15 | 2019 |
| Novel Protease Inhibitors Containing C-5-Modified bis-Tetrahydrofuranylurethane and Aminobenzothiazole as P2 and P2′ Ligands That Exert Potent Antiviral … Y Takamatsu, M Aoki, H Bulut, D Das, M Amano, VR Sheri, LC Kovari, ... Antimicrobial agents and chemotherapy 63 (8), 10.1128/aac. 00372-19, 2019 | 14 | 2019 |
| Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity H Bulut, S Hattori, H Aoki-Ogata, H Hayashi, D Das, M Aoki, DA Davis, ... Scientific Reports 10 (1), 10664, 2020 | 13 | 2020 |
| Reducing Macro‐and Microheterogeneity of N‐Glycans Enables the Crystal Structure of the Lectin and EGF‐Like Domains of Human L‐Selectin To Be Solved at 1.9 Å Resolution S Wedepohl, J Dernedde, A Vahedi‐Faridi, R Tauber, W Saenger, H Bulut ChemBioChem 18 (13), 1338-1345, 2017 | 11 | 2017 |
