| Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation L Ly, D Chan, M Aarabi, M Landry, NA Behan, AJ MacFarlane, J Trasler MHR: Basic science of reproductive medicine 23 (7), 461-477, 2017 | 123 | 2017 |
| High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism M Aarabi, MC San Gabriel, D Chan, NA Behan, M Caron, T Pastinen, ... Human molecular genetics 24 (22), 6301-6313, 2015 | 121 | 2015 |
| Developmental windows of susceptibility for epigenetic inheritance through the male germline L Ly, D Chan, JM Trasler Seminars in cell & developmental biology 43, 96-105, 2015 | 119 | 2015 |
| Reproductive and epigenetic outcomes associated with aging mouse oocytes FL Lopes, AL Fortier, N Darricarrere, D Chan, DR Arnold, JM Trasler Human molecular genetics 18 (11), 2032-2044, 2009 | 86 | 2009 |
| Strain-specific defects in testicular development and sperm epigenetic patterns in 5, 10-methylenetetrahydrofolate reductase-deficient mice D Chan, DW Cushnie, OR Neaga, AK Lawrance, R Rozen, JM Trasler Endocrinology 151 (7), 3363-3373, 2010 | 70 | 2010 |
| Epigenetic alterations in sperm DNA associated with testicular cancer treatment D Chan, G Delbès, M Landry, B Robaire, JM Trasler Toxicological Sciences 125 (2), 532-543, 2012 | 59 | 2012 |
| A high throughput screen to identify substrates for the ubiquitin ligase Rsp5 B Kus, A Gajadhar, K Stanger, R Cho, W Sun, N Rouleau, T Lee, D Chan, ... Journal of Biological Chemistry 280 (33), 29470-29478, 2005 | 54 | 2005 |
| Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation M Aarabi, KE Christensen, D Chan, D Leclerc, M Landry, L Ly, R Rozen, ... Human molecular genetics 27 (7), 1123-1135, 2018 | 46 | 2018 |
| Transient DNMT1 suppression reveals hidden heritable marks in the genome S McGraw, JX Zhang, M Farag, D Chan, M Caron, C Konermann, ... Nucleic acids research 43 (3), 1485-1497, 2015 | 46 | 2015 |
| Moderate maternal folic acid supplementation ameliorates adverse embryonic and epigenetic outcomes associated with assisted reproduction in a mouse model S Rahimi, J Martel, G Karahan, C Angle, NA Behan, D Chan, ... Human Reproduction 34 (5), 851-862, 2019 | 45 | 2019 |
| Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development KM Niles, D Chan, S La Salle, CC Oakes, JM Trasler PLoS One 6 (9), e24156, 2011 | 44 | 2011 |
| Impact of the chemotherapy cocktail used to treat testicular cancer on the gene expression profile of germ cells from male Brown-Norway rats G Delbes, D Chan, P Pakarinen, JM Trasler, BF Hales, B Robaire Biology of reproduction 80 (2), 320-327, 2009 | 41 | 2009 |
| Compromised oocyte quality and assisted reproduction contribute to sex-specific effects on offspring outcomes and epigenetic patterning L Whidden, J Martel, S Rahimi, JR Chaillet, D Chan, JM Trasler Human molecular genetics 25 (21), 4649-4660, 2016 | 40 | 2016 |
| Customized MethylC-capture sequencing to evaluate variation in the human sperm DNA methylome representative of altered folate metabolism D Chan, X Shao, MC Dumargne, M Aarabi, MM Simon, T Kwan, JL Bailey, ... Environmental health perspectives 127 (8), 087002, 2019 | 31 | 2019 |
| Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation D Chan, S McGraw, K Klein, LM Wallock, C Konermann, C Plass, P Chan, ... Human Reproduction 32 (2), 272-283, 2017 | 31 | 2017 |
| Whole-genome sequencing of H3K4me3 and DNA methylation in human sperm reveals regions of overlap linked to fertility and development R Lambrot, D Chan, X Shao, M Aarabi, T Kwan, G Bourque, S Moskovtsev, ... Cell Reports 36 (3), 2021 | 29 | 2021 |
| Protein depletion from blood plasma using a volatile buffer D Sitnikov, D Chan, E Thibaudeau, M Pinard, JM Hunter Journal of Chromatography B 832 (1), 41-46, 2006 | 23 | 2006 |
| Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations G Karahan, D Chan, K Shirane, T McClatchie, S Janssen, JM Baltz, ... Development 148 (13), dev199492, 2021 | 21 | 2021 |
| Early-life exposure to environmental contaminants perturbs the sperm epigenome and induces negative pregnancy outcomes for three generations via the paternal lineage C Maurice, M Dalvai, R Lambrot, A Deschênes, MP Scott-Boyer, ... Epigenomes 5 (2), 10, 2021 | 20 | 2021 |
| The DNMT1 intrinsically disordered domain regulates genomic methylation during development B Shaffer, S McGraw, SC Xiao, D Chan, J Trasler, JR Chaillet Genetics 199 (2), 533-541, 2015 | 19 | 2015 |
