Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches AJ McClellan, Y Xia, AM Deutschbauer, RW Davis, M Gerstein, J Frydman Cell 131 (1), 121-135, 2007 | 583 | 2007 |
Protein quality control: chaperones culling corrupt conformations AJ McClellan, S Tam, D Kaganovich, J Frydman Nature cell biology 7 (8), 736-741, 2005 | 347 | 2005 |
Folding and quality control of the VHL tumor suppressor proceed through distinct chaperone pathways AJ McClellan, MD Scott, J Frydman Cell 121 (5), 739-748, 2005 | 303 | 2005 |
The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain A Srinivasan, AJ McClellan, J Vartikar, I Marks, P Cantalupo, Y Li, ... Molecular and cellular biology 17 (8), 4761-4773, 1997 | 297 | 1997 |
The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex MW Melville, AJ McClellan, AS Meyer, A Darveau, J Frydman Molecular and cellular biology, 2003 | 173 | 2003 |
Molecular chaperones and the art of recognizing a lost cause AJ McClellan, J Frydman Nature cell biology 3 (2), E51-E53, 2001 | 158 | 2001 |
Cellular functions and molecular mechanisms of non-lysine ubiquitination AJ McClellan, SH Laugesen, L Ellgaard Open Biology 9 (9), 190147, 2019 | 144 | 2019 |
Identification of the TRiC/CCT substrate binding sites uncovers the function of subunit diversity in eukaryotic chaperonins C Spiess, EJ Miller, AJ McClellan, J Frydman Molecular cell 24 (1), 25-37, 2006 | 130 | 2006 |
Specific molecular chaperone interactions and an ATP-dependent conformational change are required during posttranslational protein translocation into the yeast ER AJ McClellan, JB Endres, JP Vogel, D Palazzi, MD Rose, JL Brodsky Molecular biology of the cell 9 (12), 3533-3545, 1998 | 118 | 1998 |
Mutation of the ATP-Binding Pocket of SSA1 Indicates That a Functional Interaction Between Ssa1p and Ydj1p Is Required for Post-translational Translocation Into … AJ McClellan, JL Brodsky Genetics 156 (2), 501-512, 2000 | 71 | 2000 |
Heterozygous yeast deletion collection screens reveal essential targets of Hsp90 EA Franzosa, V Albanèse, J Frydman, Y Xia, AJ McClellan PLoS One 6 (11), e28211, 2011 | 35 | 2011 |
Facilitating growth through frustration: using genomics research in a course-based undergraduate research experience D Lopatto, AG Rosenwald, JR DiAngelo, AT Hark, M Skerritt, M Wawersik, ... Journal of microbiology & biology education 21 (1), 10.1128/jmbe. v21i1. 2005, 2020 | 34 | 2020 |
Mitochondrial Hsp70 cannot replace BiP in driving protein translocation into the yeast endoplasmic reticulum JL Brodsky, M Bäuerle, M Horst, AJ McClellan FEBS letters 435 (2-3), 183-186, 1998 | 15 | 1998 |
Evidence for interaction between Hsp90 and the ER membrane complex T Kudze, C Mendez-Dorantes, CS Jalloh, AJ McClellan Cell Stress and Chaperones 23 (5), 1101-1115, 2018 | 12 | 2018 |
Student attitudes contribute to the effectiveness of a genomics CURE D Lopatto, AG Rosenwald, RC Burgess, C Silver Key, M Van Stry, ... Journal of Microbiology & Biology Education 23 (2), e00208-21, 2022 | 8 | 2022 |
Quality control of protein folding in the cytosol AJ McClellan Wilvey, 2012 | 4 | 2012 |
Yeast require an intact tryptophan biosynthesis pathway and exogenous tryptophan for resistance to sodium dodecyl sulfate AJ McClellan, LM Ammons, LR Bingham, S Callery, E Corley, KA Crowe, ... Journal of Student Research 4 (1), 74-82, 2015 | 2 | 2015 |
The specificity and ATP requirements of molecular chaperones during protein translocation into the yeast ER JL Brodsky, A McClellan, J Goeckeler, J Endres Molecular Biology of the Cell 7, 2541-2541, 1996 | 2 | 1996 |
The requirement for ATP and specific hsc70-DnaJ homolog interactions during protein translocation into the yeast ER AJ McClellan, JB Endres, JL Brodsky MOLECULAR BIOLOGY OF THE CELL 8, 1140-1140, 1997 | 1 | 1997 |
2nd International Symposium on the Chaperone Code, 2023 J Buchner, MJ Alasady, SJ Backe, BSJ Blagg, RL Carpenter, G Colombo, ... Cell Stress and Chaperones, 2024 | | 2024 |