VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma J Zhang, T Wu, J Simon, M Takada, R Saito, C Fan, XD Liu, E Jonasch, ... Science 361 (6399), 290-295, 2018 | 153 | 2018 |
mRNA delivery of a bispecific single‐domain antibody to polarize tumor‐associated macrophages and synergize immunotherapy against liver malignancies Y Wang, K Tiruthani, S Li, M Hu, G Zhong, Y Tang, S Roy, L Zhang, J Tan, ... Advanced Materials 33 (23), 2007603, 2021 | 107 | 2021 |
Hypoxia-driven effects in cancer: characterization, mechanisms, and therapeutic implications R Shi, C Liao, Q Zhang Cells 10 (3), 678, 2021 | 92 | 2021 |
TBK1 is a Synthetic Lethal Target in Cancer with VHL Loss QZ Lianxin Hu, Haibiao Xie, Xijuan Liu, Frances Potjewyd, Lindsey I James ... Cancer Discovery, 2019 | 89* | 2019 |
Nitrogen regulator GlnR controls uptake and utilization of non-phosphotransferase-system carbon sources in actinomycetes CH Liao, L Yao, Y Xu, WB Liu, Y Zhou, BC Ye Proceedings of the National Academy of Sciences 112 (51), 15630-15635, 2015 | 78 | 2015 |
Tumor hypoxia: From basic knowledge to therapeutic implications C Liao, X Liu, C Zhang, Q Zhang Seminars in cancer biology 88, 172-186, 2023 | 55 | 2023 |
GlnR-mediated regulation of nitrogen metabolism in the actinomycete Saccharopolyspora erythraea LL Yao, CH Liao, G Huang, Y Zhou, S Rigali, B Zhang, BC Ye Applied microbiology and biotechnology 98, 7935-7948, 2014 | 54 | 2014 |
Understanding the oxygen-sensing pathway and its therapeutic implications in diseases C Liao, Q Zhang The American journal of pathology 190 (8), 1584-1595, 2020 | 50 | 2020 |
Three genes encoding citrate synthases in Saccharopolyspora erythraea are regulated by the global nutrient‐sensing regulators GlnR, DasR, and CRP CH Liao, L Yao, BC Ye Molecular microbiology 94 (5), 1065-1084, 2014 | 43 | 2014 |
Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer C Liao, Y Zhang, C Fan, LE Herring, J Liu, JW Locasale, M Takada, ... Cancer discovery 10 (11), 1706-1721, 2020 | 41 | 2020 |
USP37 promotes deubiquitination of HIF2α in kidney cancer K Hong, L Hu, X Liu, JM Simon, TS Ptacek, X Zheng, C Liao, AS Baldwin, ... Proceedings of the National Academy of Sciences 117 (23), 13023-13032, 2020 | 32 | 2020 |
Histone H3 proline 16 hydroxylation regulates mammalian gene expression X Liu, J Wang, JA Boyer, W Gong, S Zhao, L Xie, Q Wu, C Zhang, K Jain, ... Nature genetics 54 (11), 1721-1735, 2022 | 29 | 2022 |
An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma J Zhou, JM Simon, C Liao, C Zhang, L Hu, G Zurlo, X Liu, C Fan, ... Molecular cell 82 (16), 3030-3044. e8, 2022 | 29 | 2022 |
ZHX2 promotes HIF1α oncogenic signaling in triple-negative breast cancer W Fang, C Liao, R Shi, JM Simon, TS Ptacek, G Zurlo, Y Ye, L Han, C Fan, ... Elife 10, e70412, 2021 | 27 | 2021 |
DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea CH Liao, Y Xu, S Rigali, BC Ye Applied microbiology and biotechnology 99, 10215-10224, 2015 | 27 | 2015 |
Control of chitin and N-acetylglucosamine utilization in Saccharopolyspora erythraea C Liao, S Rigali, CL Cassani, E Marcellin, LK Nielsen, BC Ye Microbiology 160 (9), 1914-1928, 2014 | 25 | 2014 |
GlnR and PhoP directly regulate the transcription of genes encoding starch-degrading, amylolytic enzymes in Saccharopolyspora erythraea Y Xu, CH Liao, LL Yao, X Ye, BC Ye Applied and environmental microbiology 82 (23), 6819-6830, 2016 | 24 | 2016 |
USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer H Xie, J Zhou, X Liu, Y Xu, AJ Hepperla, JM Simon, T Wang, H Yao, ... Proceedings of the National Academy of Sciences 119 (36), e2119854119, 2022 | 22 | 2022 |
Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers C Liao, CR Glodowski, C Fan, J Liu, KR Mott, A Kaushik, H Vu, ... Cancer research, 2021 | 12 | 2021 |
FOXP1 and KLF2 reciprocally regulate checkpoints of stem-like to effector transition in CAR T cells Z Zhu, G Lou, XL Teng, H Wang, Y Luo, W Shi, K Yihunie, S Hao, ... Nature immunology 25 (1), 117-128, 2024 | 9 | 2024 |