Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation W Kim, R Kim, G Park, JW Park, JE Kim Journal of Biological Chemistry 287 (8), 5588-5599, 2012 | 150 | 2012 |
DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells F Zhao, W Kim, JA Kloeber, Z Lou Experimental & Molecular Medicine 52 (10), 1705-1714, 2020 | 136 | 2020 |
The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle W Kim, M Choi, JE Kim Cell Cycle 13 (5), 726-738, 2014 | 134 | 2014 |
AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells MG Cheon, W Kim, M Choi, JE Kim Cancer letters 356 (2), 637-645, 2015 | 78 | 2015 |
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair Q Zhou, J Huang, C Zhang, F Zhao, W Kim, X Tu, Y Zhang, S Nowsheen, ... Nature communications 11 (1), 2639, 2020 | 61 | 2020 |
Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells M Choi, W Kim, MG Cheon, CW Lee, JE Kim Cancer letters 357 (2), 591-601, 2015 | 60 | 2015 |
MET amplification attenuates lung tumor response to immunotherapy by inhibiting STING Y Zhang, Q Yang, X Zeng, M Wang, S Dong, B Yang, X Tu, T Wei, W Xie, ... Cancer discovery 11 (11), 2726-2737, 2021 | 58 | 2021 |
CHK2-FOXK axis promotes transcriptional control of autophagy programs Y Chen, J Wu, G Liang, G Geng, F Zhao, P Yin, S Nowsheen, C Wu, Y Li, ... Science advances 6 (1), eaax5819, 2020 | 53 | 2020 |
Tandem deubiquitination and acetylation of SPRTN promotes DNA-protein crosslink repair and protects against aging J Huang, Q Zhou, M Gao, S Nowsheen, F Zhao, W Kim, Q Zhu, Y Kojima, ... Molecular cell 79 (5), 824-835. e5, 2020 | 52 | 2020 |
USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2 J Wu, Y Chen, G Geng, L Li, P Yin, S Nowsheen, Y Li, C Wu, J Liu, F Zhao, ... Cancer Letters 449, 114-124, 2019 | 50 | 2019 |
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling G Guo, M Gao, X Gao, B Zhu, J Huang, X Tu, W Kim, F Zhao, Q Zhou, ... Nature communications 12 (1), 2187, 2021 | 47 | 2021 |
DNA damage and its role in cancer therapeutics J Moon, I Kitty, K Renata, S Qin, F Zhao, W Kim International Journal of Molecular Sciences 24 (5), 4741, 2023 | 44 | 2023 |
A novel UCHL3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair Z Song, X Tu, Q Zhou, J Huang, Y Chen, J Liu, SB Lee, W Kim, ... Cell Death & Disease 10 (6), 398, 2019 | 42 | 2019 |
CCAR2/DBC1 and Hsp60 positively regulate expression of survivin in neuroblastoma cells W Kim, J Ryu, JE Kim International Journal of Molecular Sciences 20 (1), 131, 2019 | 41 | 2019 |
METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma X Zeng, F Zhao, G Cui, Y Zhang, RA Deshpande, Y Chen, M Deng, ... Nature Cancer 3 (9), 1088-1104, 2022 | 39 | 2022 |
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization Y Yan, Z Xu, J Huang, G Guo, M Gao, W Kim, X Zeng, JA Kloeber, Q Zhu, ... Nucleic acids research 48 (22), 12711-12726, 2020 | 38 | 2020 |
Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage W Kim, JE Kim Cancer letters 333 (2), 180-186, 2013 | 33 | 2013 |
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection F Zhao, W Kim, H Gao, C Liu, Y Zhang, Y Chen, M Deng, Q Zhou, ... Nature Cell Biology 23 (8), 894-904, 2021 | 32 | 2021 |
The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation YH Min, W Kim, JE Kim Oncotarget 7 (51), 84718, 2016 | 32 | 2016 |
USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP M Gao, G Guo, J Huang, JA Kloeber, F Zhao, M Deng, X Tu, W Kim, ... Nature communications 11 (1), 5362, 2020 | 25 | 2020 |