Structural dynamics of Zika virus NS2B-NS3 protease binding to dipeptide inhibitors Y Li, Z Zhang, WW Phoo, YR Loh, W Wang, S Liu, MW Chen, AW Hung, ... Structure 25 (8), 1242-1250. e3, 2017 | 112 | 2017 |
Isocitrate dehydrogenase variants in cancer—Cellular consequences and therapeutic opportunities S Liu, T Cadoux-Hudson, CJ Schofield Current opinion in chemical biology 57, 122-134, 2020 | 46 | 2020 |
Structural and ligand-binding analysis of the YAP-binding domain of transcription factor TEAD4 Y Li, S Liu, EY Ng, R Li, A Poulsen, J Hill, AV Pobbati, AW Hung, W Hong, ... Biochemical Journal 475 (12), 2043-2055, 2018 | 38 | 2018 |
Roles of metal ions in the selective inhibition of oncogenic variants of isocitrate dehydrogenase 1 S Liu, MI Abboud, T John, V Mikhailov, I Hvinden, J Walsby-Tickle, X Liu, ... Communications Biology 4 (1), 1243, 2021 | 23 | 2021 |
Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease JP Quek, S Liu, Z Zhang, Y Li, EY Ng, YR Loh, AW Hung, D Luo, CB Kang Antiviral Research 175, 104707, 2020 | 20 | 2020 |
DNA-encoded library-enabled discovery of proximity-inducing small molecules JW Mason, YT Chow, L Hudson, A Tutter, G Michaud, MV Westphal, ... Nature Chemical Biology 20 (2), 170-179, 2024 | 19 | 2024 |
Rational screening for cooperativity in small-molecule inducers of protein–protein associations S Liu, B Tong, JW Mason, JM Ostrem, A Tutter, BK Hua, SA Tang, ... Journal of the American Chemical Society 145 (42), 23281-23291, 2023 | 18 | 2023 |
Escherichia coli topoisomerase IV E subunit and an inhibitor binding mode revealed by NMR spectroscopy Y Li, YL Wong, FM Ng, B Liu, YX Wong, ZY Poh, S Liu, SW Then, MY Lee, ... Journal of Biological Chemistry 291 (34), 17743-17753, 2016 | 17 | 2016 |
Diversity-oriented synthesis encoded by deoxyoligonucleotides L Hudson, JW Mason, MV Westphal, MJR Richter, JR Thielman, BK Hua, ... Nature communications 14 (1), 4930, 2023 | 6 | 2023 |
Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2 X Liu, R Reinbold, S Liu, RA Herold, P Rabe, S Duclos, RB Yadav, ... Journal of Biological Chemistry 299 (2), 2023 | 5 | 2023 |
Structure–activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase J Anantharajan, N Baburajendran, G Lin, YY Loh, W Xu, NHB Ahmad, ... Protein Science 31 (2), 422-431, 2022 | 5 | 2022 |
Differentiating inhibition selectivity and binding affinity of isocitrate dehydrogenase 1 variant inhibitors S Liu, M Abboud, V Mikhailov, X Liu, R Reinbold, CJ Schofield Journal of Medicinal Chemistry 66 (7), 5279-5288, 2023 | 4 | 2023 |
Backbone resonance assignments for the SET domain of human methyltransferase NSD3 in complex with its cofactor Y Li, HQ Ng, A Ngo, S Liu, YW Tan, PZ Kwek, AW Hung, J Joy, J Hill, ... Biomolecular NMR Assignments 11, 225-229, 2017 | 2 | 2017 |