| A deep learning approach to antibiotic discovery JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz, NM Donghia, ... Cell 180 (4), 688-702. e13, 2020 | 2103 | 2020 |
| CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database BP Alcock, W Huynh, R Chalil, KW Smith, AR Raphenya, MA Wlodarski, ... Nucleic acids research 51 (D1), D690-D699, 2023 | 736 | 2023 |
| Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics CR MacNair, JM Stokes, LA Carfrae, AA Fiebig-Comyn, BK Coombes, ... Nature communications 9 (1), 458, 2018 | 295 | 2018 |
| Uncovering the hidden antibiotic potential of cannabis MA Farha, OM El-Halfawy, RT Gale, CR MacNair, LA Carfrae, X Zhang, ... ACS infectious diseases 6 (3), 338-346, 2020 | 140 | 2020 |
| Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens LA Carfrae, CR MacNair, CM Brown, CN Tsai, BS Weber, S Zlitni, VN Rao, ... Nature Microbiology 5 (1), 93-101, 2020 | 45 | 2020 |
| Inhibiting fatty acid synthesis overcomes colistin resistance LA Carfrae, K Rachwalski, S French, R Gordzevich, L Seidel, CN Tsai, ... Nature Microbiology 8 (6), 1026-1038, 2023 | 34 | 2023 |
| Overcoming acquired and native macrolide resistance with bicarbonate MA Farha, CR MacNair, LA Carfrae, SS El Zahed, MJ Ellis, HKR Tran, ... ACS Infectious Diseases 6 (10), 2709-2718, 2020 | 26 | 2020 |
| Preclinical development of pentamidine analogs identifies a potent and nontoxic antibiotic adjuvant CR MacNair, MA Farha, MH Serrano-Wu, KK Lee, B Hubbard, JP Côté, ... ACS Infectious Diseases 8 (4), 768-777, 2022 | 22 | 2022 |
| Antibacterial activity of metergoline analogues: revisiting the ergot alkaloid scaffold for antibiotic discovery JW Johnson, MJ Ellis, ZA Piquette, C MacNair, L Carfrae, T Bhando, ... ACS Medicinal Chemistry Letters 13 (2), 284-291, 2022 | 19 | 2022 |
| Nutrient stress is a target for new antibiotics LA Carfrae, ED Brown Trends in microbiology 31 (6), 571-585, 2023 | 14 | 2023 |
| Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium MJ Ellis, LA Carfrae, CR Macnair, RS Trussler, ED Brown, DB Haniford RNA biology 15 (2), 176-181, 2018 | 9 | 2018 |
| Uncovering the hidden antibiotic potential of Cannabis. BioRxiv, 833392 MA Farha, OM El-Halfawy, RT Gale, CR MacNair, LA Carfrae, X Zhang, ... | 5 | 2020 |
| Polynuclear ruthenium complexes are effective antibiotics against Pseudomonas aeruginosa BS Weber, LA Carfrae, JJ Woods, K Klobucar, NP Bigham, CR MacNair, ... bioRxiv, 2022.08. 11.503708, 2022 | 1 | 2022 |
| Exploiting the fitness cost of metallo-β-lactamase expression can overcome antibiotic resistance in bacterial pathogens MM Tu, LA Carfrae, K Rachwalski, S French, D Catacutan, R Gordzevich, ... Nature Microbiology, 1-13, 2025 | | 2025 |
| The aryl hydrocarbon receptor and FOS mediate cytotoxicity induced by Acinetobacter baumannii C Kew, C Prieto-Garcia, A Bhattacharya, M Tietgen, CR MacNair, ... Nature Communications 15 (1), 7939, 2024 | | 2024 |
| Research Tutorial Report JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz, NM Donghia, ... Cell 180 (4), P688-702, 2024 | | 2024 |
| The fitness cost of metallo-β-lactamase expression is a potential target for new therapeutic approaches to carbapenem resistance M Tu, L Carfrae, K Rachwalski, S French, D Catacutan, R Gordzevich, ... | | 2023 |
| Research briefing L Carfrae, E Brown Nature 8, 1006-1007, 2023 | | 2023 |
| Methods for inhibiting microbe growth E Brown, M Farha, C MacNair, L Carfrae US Patent 11,400,106, 2022 | | 2022 |
| EXPLOITING BACTERIAL NUTRIENT STRESS IN THE TREATMENT OF ANTIBIOTIC-RESISTANT PATHOGENS LA Carfrae | | 2022 |
