Autophagy induction via STING trafficking is a primordial function of the cGAS pathway X Gui, H Yang, T Li, X Tan, P Shi, M Li, F Du, ZJ Chen Nature 567 (7747), 262-266, 2019 | 851 | 2019 |
Detection of microbial infections through innate immune sensing of nucleic acids X Tan, L Sun, J Chen, ZJ Chen Annual review of microbiology 72, 447-478, 2018 | 370 | 2018 |
A kinase-independent role for EGF receptor in autophagy initiation X Tan, N Thapa, Y Sun, RA Anderson Cell 160 (1), 145-160, 2015 | 237 | 2015 |
Stress-induced EGFR trafficking: mechanisms, functions, and therapeutic implications X Tan, PF Lambert, AC Rapraeger, RA Anderson Trends in cell biology 26 (5), 352-366, 2016 | 184 | 2016 |
A phosphoinositide signalling pathway mediates rapid lysosomal repair JX Tan, T Finkel Nature 609 (7928), 815-821, 2022 | 122 | 2022 |
Emerging roles of PtdIns(4,5)P2 – beyond the plasma membrane X Tan, N Thapa, S Choi, RA Anderson Journal of cell science 128 (22), 4047-4056, 2015 | 105 | 2015 |
Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sorting Y Sun, AC Hedman, X Tan, NJ Schill, RA Anderson Developmental cell 25 (2), 144-155, 2013 | 95 | 2013 |
Mitochondria as intracellular signaling platforms in health and disease JX Tan, T Finkel Journal of Cell Biology 219 (5), 2020 | 90 | 2020 |
PIP kinases define PI4, 5P2 signaling specificity by association with effectors S Choi, N Thapa, X Tan, AC Hedman, RA Anderson Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 87 | 2015 |
LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation X Tan, Y Sun, N Thapa, Y Liao, AC Hedman, RA Anderson The EMBO journal 34 (4), 475-490, 2015 | 82 | 2015 |
PtdIns (4, 5) P2 signaling regulates ATG14 and autophagy X Tan, N Thapa, Y Liao, S Choi, RA Anderson Proceedings of the National Academy of Sciences 113 (39), 10896-10901, 2016 | 70 | 2016 |
Phosphatidylinositol phosphate 5-kinase Iγ and phosphoinositide 3-kinase/Akt signaling couple to promote oncogenic growth N Thapa, S Choi, X Tan, T Wise, RA Anderson Journal of Biological Chemistry 290 (30), 18843-18854, 2015 | 46 | 2015 |
The hidden conundrum of phosphoinositide signaling in cancer N Thapa, X Tan, S Choi, PF Lambert, AC Rapraeger, RA Anderson Trends in cancer 2 (7), 378-390, 2016 | 40 | 2016 |
PIP kinases from the cell membrane to the nucleus M Schramp, A Hedman, W Li, X Tan, R Anderson Phosphoinositides I: Enzymes of Synthesis and Degradation, 25-59, 2012 | 37 | 2012 |
Lysosomal quality control: molecular mechanisms and therapeutic implications H Yang, JX Tan Trends in Cell Biology 33 (9), 749-764, 2023 | 25 | 2023 |
Phosphatidylinositol phosphate 5-kinase Iγi2 in association with Src controls anchorage-independent growth of tumor cells N Thapa, S Choi, A Hedman, X Tan, RA Anderson Journal of Biological Chemistry 288 (48), 34707-34718, 2013 | 19 | 2013 |
PIPKIγ and talin couple phosphoinositide and adhesion signaling to control the epithelial to mesenchymal transition N Thapa, X Tan, S Choi, T Wise, RA Anderson Oncogene 36 (7), 899-911, 2017 | 18 | 2017 |
Modulation of lysosomal function as a therapeutic approach for coronaviral infections Y Liu, T Lear, M Larsen, B Lin, Q Cao, I Alfaras, J Kennerdell, L Salminen, ... Research Square, 2021 | 11 | 2021 |
Lysosomes in senescence and aging JX Tan, T Finkel EMBO reports 24 (11), e57265, 2023 | 9 | 2023 |
A conserved ion channel function of STING mediates noncanonical autophagy and cell death J Xun, Z Zhang, B Lv, D Lu, H Yang, G Shang, JX Tan EMBO reports, 1-26, 2024 | 7 | 2024 |