Receptor specificity of the fibroblast growth factor family: the complete mammalian FGF family X Zhang, OA Ibrahimi, SK Olsen, H Umemori, M Mohammadi, DM Ornitz Journal of Biological Chemistry 281 (23), 15694-15700, 2006 | 1410 | 2006 |
Structural basis for fibroblast growth factor receptor activation M Mohammadi, SK Olsen, OA Ibrahimi Cytokine & growth factor reviews 16 (2), 107-137, 2005 | 952 | 2005 |
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members R Goetz, A Beenken, OA Ibrahimi, J Kalinina, SK Olsen, AV Eliseenkova, ... Molecular and cellular biology 27 (9), 3417-3428, 2007 | 685 | 2007 |
Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... Science advances 6 (42), eabd4596, 2020 | 482* | 2020 |
Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism N Pitteloud, R Quinton, S Pearce, T Raivio, J Acierno, A Dwyer, ... The Journal of clinical investigation 117 (2), 457-463, 2007 | 434 | 2007 |
Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs SK Olsen, M Garbi, N Zampieri, AV Eliseenkova, DM Ornitz, M Goldfarb, ... Journal of Biological Chemistry 278 (36), 34226-34236, 2003 | 383 | 2003 |
Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity SK Olsen, OA Ibrahimi, A Raucci, F Zhang, AV Eliseenkova, A Yayon, ... Proceedings of the National Academy of Sciences 101 (4), 935-940, 2004 | 258 | 2004 |
Active site remodelling accompanies thioester bond formation in the SUMO E1 SK Olsen, AD Capili, X Lu, DS Tan, CD Lima Nature 463 (7283), 906-912, 2010 | 246 | 2010 |
Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain SK Olsen, JYH Li, C Bromleigh, AV Eliseenkova, OA Ibrahimi, Z Lao, ... Genes & development 20 (2), 185-198, 2006 | 232 | 2006 |
A protein canyon in the FGF–FGF receptor dimer selects from an a la carte menu of heparan sulfate motifs M Mohammadi, SK Olsen, R Goetz Current opinion in structural biology 15 (5), 506-516, 2005 | 223 | 2005 |
Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer SK Olsen, CD Lima Molecular cell 49 (5), 884-896, 2013 | 202 | 2013 |
Crystal structure of the interleukin-15· interleukin-15 receptor α complex: insights into trans and cis presentation SK Olsen, N Ota, S Kishishita, M Kukimoto-Niino, K Murayama, ... Journal of Biological Chemistry 282 (51), 37191-37204, 2007 | 137 | 2007 |
Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity D Lv, P Pal, X Liu, Y Jia, D Thummuri, P Zhang, W Hu, J Pei, Q Zhang, ... Nature communications 12 (1), 6896, 2021 | 108 | 2021 |
Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes X Lu, SK Olsen, AD Capili, JS Cisar, CD Lima, DS Tan Journal of the American Chemical Society 132 (6), 1748-1749, 2010 | 92 | 2010 |
Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR … OA Ibrahimi, BK Yeh, AV Eliseenkova, F Zhang, SK Olsen, M Igarashi, ... Molecular and cellular biology, 2005 | 91 | 2005 |
TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis AN Woosley, AC Dalton, GS Hussey, BV Howley, BK Mohanty, S Grelet, ... Oncogene 38 (20), 3794-3811, 2019 | 83 | 2019 |
Targeting SARS-CoV-2 proteases for COVID-19 antiviral development Z Lv, KE Cano, L Jia, M Drag, TT Huang, SK Olsen Frontiers in Chemistry 9, 819165, 2022 | 82 | 2022 |
Structural basis for adenylation and thioester bond formation in the ubiquitin E1 ZS Hann, C Ji, SK Olsen, X Lu, MC Lux, DS Tan, CD Lima Proceedings of the National Academy of Sciences 116 (31), 15475-15484, 2019 | 64 | 2019 |
Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme Z Lv, L Yuan, JH Atkison, KM Williams, R Vega, EH Sessions, ... Nature communications 9 (1), 5145, 2018 | 64 | 2018 |
Crystal structure of a human ubiquitin E1–ubiquitin complex reveals conserved functional elements essential for activity Z Lv, KM Williams, L Yuan, JH Atkison, SK Olsen Journal of Biological Chemistry 293 (47), 18337-18352, 2018 | 62 | 2018 |