LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, ... EMBO Mol Med, 2021 | 66 | 2021 |
Genome-wide transcriptomics identifies an early preclinical signature of prion infection S Sorce, M Nuvolone, G Russo, A Chincisan, D Heinzer, M Avar, ... PLoS pathogens 16 (6), e1008653, 2020 | 53 | 2020 |
Scaling analysis reveals the mechanism and rates of prion replication in vivo G Meisl, T Kurt, I Condado-Morales, C Bett, S Sorce, M Nuvolone, ... Nature structural & molecular biology 28 (4), 365-372, 2021 | 30 | 2021 |
Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties I Harel, YR Chen, I Ziv, PP Singh, D Heinzer, PN Negredo, ... Cell reports 43 (6), 2024 | 27 | 2024 |
Prion infection, transmission, and cytopathology modeled in a low-biohazard human cell line M Avar, D Heinzer, N Steinke, B Doğançay, R Moos, S Lugan, C Cosenza, ... Life science alliance 3 (8), 2020 | 14 | 2020 |
Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier A Keller, M Nuvolone, I Abakumova, A Chincisan, R Reimann, M Avar, ... PLoS pathogens 14 (11), e1007424, 2018 | 12 | 2018 |
High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production M Müller, M Avar, D Heinzer, M Emmenegger, A Aguzzi, L Pelkmans, ... Scientific Data 8 (1), 162, 2021 | 10 | 2021 |
An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein E Kara, A Crimi, A Wiedmer, M Emmenegger, C Manzoni, S Bandres-Ciga, ... Cell reports 35 (10), 2021 | 10 | 2021 |
An arrayed genome‐wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate‐limiting for prion propagation M Avar, D Heinzer, AM Thackray, Y Liu, M Hruska‐Plochan, S Sellitto, ... The EMBO Journal 41 (23), e112338, 2022 | 9 | 2022 |
Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference D Heinzer, M Avar, DP Pease, A Dhingra, JA Yin, E Schaper, B Doğançay, ... PLOS Pathogens, 2021 | 6 | 2021 |
HIV-1 promoter is gradually silenced when integrated into BACH2 in Jurkat T-cells A Inderbitzin, YL Kok, L Jörimann, A Kelley, K Neumann, D Heinzer, ... PeerJ 8, e10321, 2020 | 4* | 2020 |
Advancing surgical instrument safety: A screen of oxidative and alkaline prion decontaminants using real-time quaking-induced conversion with prion-coated steel beads as … D Heinzer, M Avar, M Pfammatter, R Moos, P Schwarz, MT Buhmann, ... Plos one 19 (6), e0304603, 2024 | 2* | 2024 |
Cell-Based Whole Genome RNAi Screen to Uncover Regulators of PrPC Biosynthesis and Degradation D Heinzer University of Zurich, 2021 | | 2021 |