| A “mitochondrial cascade hypothesis” for sporadic Alzheimer's disease RH Swerdlow, SM Khan Medical hypotheses 63 (1), 8-20, 2004 | 867 | 2004 |
| The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives RH Swerdlow, JM Burns, SM Khan Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014 | 827 | 2014 |
| The Alzheimer's disease mitochondrial cascade hypothesis RH Swerdlow, JM Burns, SM Khan Journal of Alzheimer's Disease 20 (s2), S265-S279, 2010 | 616 | 2010 |
| The Alzheimer's disease mitochondrial cascade hypothesis: an update RH Swerdlow, SM Khan Experimental neurology 218 (2), 308-315, 2009 | 274 | 2009 |
| Mitochondrial dysfunction in Alzheimer’s disease and the rationale for bioenergetics based therapies IG Onyango, J Dennis, SM Khan Aging and disease 7 (2), 201, 2016 | 260 | 2016 |
| Alzheimer's disease cybrids replicate β‐amyloid abnormalities through cell death pathways SM Khan, DS Cassarino, NN Abramova, PM Keeney, MK Borland, ... Annals of Neurology: Official Journal of the American Neurological …, 2000 | 237 | 2000 |
| Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores J Lecarpentier, V Silvestri, KB Kuchenbaecker, D Barrowdale, J Dennis, ... Journal of Clinical Oncology 35 (20), 2240-2250, 2017 | 195 | 2017 |
| DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination W Guo, L Jiang, S Bhasin, SM Khan, RH Swerdlow Mitochondrion 9 (4), 261-265, 2009 | 189 | 2009 |
| Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease IG Onyango, SM Khan Current Alzheimer Research 3 (4), 339-349, 2006 | 160 | 2006 |
| Caspase-9 is activated in a cytochrome c-independent manner early during TNFα-induced apoptosis in murine cells MA McDonnell, D Wang, SM Khan, MG Vander Heiden, A Kelekar Cell Death & Differentiation 10 (9), 1005-1015, 2003 | 132 | 2003 |
| Mitochondria in the pathophysiology of Alzheimer’s and Parkinson’s diseases IG Onyango, SM Khan, JP Bennett Jr Front Biosci (Landmark Ed) 22 (5), 854-72, 2017 | 125 | 2017 |
| Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model PM Keeney, CK Quigley, LD Dunham, CM Papageorge, S Iyer, ... Human gene therapy 20 (8), 897-907, 2009 | 106 | 2009 |
| Inhibition by R (+) or S (–) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH‐SY5Y neuroblastoma NA Abramova, DS Cassarino, SM Khan, TW Painter, JP Bennett Jr Journal of neuroscience research 67 (4), 494-500, 2002 | 92 | 2002 |
| Development of mitochondrial gene replacement therapy SM Khan, JP Bennett Journal of bioenergetics and biomembranes 36, 387-393, 2004 | 88 | 2004 |
| Mitochondrial genomic contribution to mitochondrial dysfunction in Alzheimer's disease I Onyango, S Khan, B Miller, R Swerdlow, P Trimmer, J Bennett Jr Journal of Alzheimer's Disease 9 (2), 183-193, 2006 | 73 | 2006 |
| Mitochondrial microheteroplasmy and a theory of aging and age-related disease RM Smigrodzki, SM Khan Rejuvenation research 8 (3), 172-198, 2005 | 71 | 2005 |
| Nonviral vectors for delivering polynucleotides to target tissues S Khan US Patent 8,133,733, 2012 | 63 | 2012 |
| Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31. 2 N Orr, F Dudbridge, N Dryden, S Maguire, D Novo, E Perrakis, N Johnson, ... Human molecular genetics 24 (10), 2966-2984, 2015 | 60 | 2015 |
| Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and … RR Thomas, SM Khan, FR Portell, RM Smigrodzki, JP Bennett Jr Mitochondrion 11 (1), 108-118, 2011 | 58 | 2011 |
| Cell and animal models of mtDNA biology: progress and prospects SM Khan, RM Smigrodzki, RH Swerdlow American Journal of Physiology-Cell Physiology 292 (2), C658-C669, 2007 | 58 | 2007 |
