Mycophenolic acid and its metabolites in kidney transplant recipients: a semimechanistic enterohepatic circulation model to improve estimating exposure M Okour, PA Jacobson, MA Ahmed, AK Israni, RC Brundage The Journal of Clinical Pharmacology 58 (5), 628-639, 2018 | 34 | 2018 |
Amikacin pharmacokinetic-pharmacodynamic analysis in pediatric cancer patients AA Alhadab, MA Ahmed, RC Brundage Antimicrobial agents and chemotherapy 62 (4), 10.1128/aac. 01781-17, 2018 | 22 | 2018 |
An integrated PK‐PD model for cortisol and the 17‐hydroxyprogesterone and androstenedione biomarkers in children with congenital adrenal hyperplasia M Al‐Kofahi, MA Ahmed, MM Jaber, TN Tran, BA Willis, CL Zimmerman, ... British Journal of Clinical Pharmacology 87 (3), 1098-1110, 2021 | 21 | 2021 |
Development of a model‐based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy K Lingineni, V Aggarwal, JF Morales, DJ Conrado, D Corey, C Vong, ... CPT: Pharmacometrics & Systems Pharmacology 11 (3), 318-332, 2022 | 18 | 2022 |
Orphan drug development: the increasing role of clinical pharmacology MA Ahmed, M Okour, R Brundage, RV Kartha Journal of Pharmacokinetics and Pharmacodynamics 46, 395-409, 2019 | 18 | 2019 |
Stable isotope pharmacokinetic studies provide insight into effects of age, sex, and weight on levothyroxine metabolism IR Younis, MA Ahmed, KD Burman, OP Soldin, J Jonklaas Thyroid 28 (1), 41-49, 2018 | 18 | 2018 |
A hierarchical Bayesian approach for combining pharmacokinetic/pharmacodynamic modeling and Phase IIa trial design in orphan drugs: Treating adrenoleukodystrophy with Lorenzo’s oil C Basu, MA Ahmed, RV Kartha, RC Brundage, GV Raymond, JC Cloyd, ... Journal of biopharmaceutical statistics 26 (6), 1025-1039, 2016 | 13 | 2016 |
A model‐based approach to assess the exposure–response relationship of Lorenzo's oil in adrenoleukodystrophy MA Ahmed, RV Kartha, RC Brundage, J Cloyd, C Basu, BP Carlin, ... British Journal of Clinical Pharmacology 81 (6), 1058-1066, 2016 | 11 | 2016 |
Model‐Informed Approaches and Innovative Clinical Trial Design for Adeno‐Associated Viral Vector‐Based Gene Therapy Product Development: A White Paper A Mitra, MA Ahmed, R Krishna, K Sun, FD Gibbons, O Campagne, ... Clinical Pharmacology & Therapeutics 114 (3), 515-529, 2023 | 9 | 2023 |
Clinical pharmacology in drug development for rare diseases in neurology: contributions and opportunities B Abuasal, MA Ahmed, P Patel, S Albusaysi, S Sabarinath, R Uppoor, ... Clinical Pharmacology & Therapeutics 111 (4), 786-798, 2022 | 8 | 2022 |
Lanadelumab in patients 2 to less than 12 years old with hereditary angioedema: results from the phase 3 SPRING study M Maurer, WR Lumry, HH Li, E Aygören-Pürsün, PJ Busse, J Jacobs, ... The Journal of Allergy and Clinical Immunology: In Practice 12 (1), 201-211. e6, 2024 | 7 | 2024 |
Pivotal considerations for optimal deployment of healthy volunteers in oncology drug development MA Ahmed, C Patel, N Drezner, W Helms, W Tan, D Stypinski Clinical and Translational Science 13 (1), 31-40, 2020 | 6 | 2020 |
Concordance of exposure changes because of renal impairment between results of dedicated renal impairment studies and population pharmacokinetic predictions MA Ahmed, SN Kalaria, IR Younis The Journal of Clinical Pharmacology 61 (10), 1324-1333, 2021 | 3 | 2021 |
A proposal of conducting bioequivalence trials with gastric pH modulators for two oral formulations demonstrating different dissolution profiles at elevated pH H Zhu, X Chen, M Ahmed, Y Wang, Q Liu, RS Uppoor, C Kuemmel, ... Clinical and Translational Science 12 (6), 564-572, 2019 | 2 | 2019 |
A model-based pharmacokinetic/pharmacodynamic analysis of hydrocortisone, 17-hydroxyprogesterone (17OHP), and androstenedione (D4A) in children with congenital adrenal … MA Ahmed, K Sarafoglou, M Al-Kofahi, MT Gonzalez-Bolanos, ... JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 43, S89-S89, 2016 | 2 | 2016 |
Advancing the utilization of real‐world data and real‐world evidence in clinical pharmacology and translational research—Proceedings from the ASCPT 2023 preconference workshop J Liu, K Rowland‐Yeo, A Winterstein, S Dagenais, Q Liu, JS Barrett, ... Clinical and Translational Science 17 (4), e13785, 2024 | 1 | 2024 |
Application of Clinical Pharmacology Principles in Drug Development of Modified‐Release Products: Leveraging Exposure‐Response Information to Support Approval BS AbuAsal, SS Hamed, MA Ahmed, L Al‐Mansour, R Uppoor, M Mehta The Journal of Clinical Pharmacology 60 (11), 1441-1452, 2020 | 1 | 2020 |
Covariate modeling in pharmacometrics: General points for consideration K Sanghavi, J Ribbing, JA Rogers, MA Ahmed, MO Karlsson, N Holford, ... CPT: Pharmacometrics & Systems Pharmacology 13 (5), 710-728, 2024 | | 2024 |
Baseline levels of neurofilament light chain in the cerebrospinal fluid correlate with clinical outcomes in patients with MPS II from a phase 2/3 clinical trial (NCT02055118 … C Argueta, M Ahmed, OR Brekk, S McDonnell, L Pan, T Plavina, ... Molecular Genetics and Metabolism 141 (2), 107752, 2024 | | 2024 |
Clinical profile of (HAE) from a community allergy clinic in India M Ahmed ALLERGY 78, 2023 | | 2023 |